Today we discussed Lupus Nephritis Pathology π¬at @GlomCon Glomerular Diseases Fellowship with Dr Stillman and Dr @VBijol
β Here are some amazing pearls on LN:
#NephTwitter #PathTwitter #NephPearls
β Here are some amazing pearls on LN:
#NephTwitter #PathTwitter #NephPearls
@GlomCon @VBijol Lesions that are highly characteristic of LN:
π’ IF: IgG dominant glomerular deposits associated with a "full house"
- IgG, IgA, IgM, C3 & C1q
π΅ EM: multiple site deposition
- Subendothelial, subepithelial, intramembranous and mesangial
#NephTwitter #PathTwitter #NephPearls
π’ IF: IgG dominant glomerular deposits associated with a "full house"
- IgG, IgA, IgM, C3 & C1q
π΅ EM: multiple site deposition
- Subendothelial, subepithelial, intramembranous and mesangial
#NephTwitter #PathTwitter #NephPearls
Lesions that are highly characteristic of LN:
π’ Extra-glomerular IC deposition:
- TBM, interstitium and blood vessels
π΅ Prominent tubulo-reticular inclusions
#NephTwitter #PathTwitter #NephPearls
π’ Extra-glomerular IC deposition:
- TBM, interstitium and blood vessels
π΅ Prominent tubulo-reticular inclusions
#NephTwitter #PathTwitter #NephPearls
Immune complex location of deposition determines histologic pattern π¬
π’ Mesangial β‘οΈ Class I, Class II
π‘ Endothelial β‘οΈ Class III, Class IV
π΄ Epithelial β‘οΈ Class V
#NephTwitter #PathTwitter #NephPearls
π’ Mesangial β‘οΈ Class I, Class II
π‘ Endothelial β‘οΈ Class III, Class IV
π΄ Epithelial β‘οΈ Class V
#NephTwitter #PathTwitter #NephPearls
β’ β’ β’
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