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Monica Gandhi MD, MPH Profile picture
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29 Oct, 6 tweets, 2 min read
This article is interesting at @sfchronicle because it discusses concept of risk analysis and our broken relationship with it after vaccination.
sfchronicle.com/opinion/openfo… v Image
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"Rather, it is whether officials are using sound scientific reasoning and quantitative methods in their policy decisions" Image
Reminds me of this article which I would encourage you to read to think about our broken relationship with math right now
persuasion.community/p/how-to-fix-o…
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Reason CRITICAL for public health officials (and elected) to consider effects of their dictums after vaccination is that we want to 1) encourage vax; 2) have some trust in public health left for other public health needs. What metrics make sense after vax?
washingtonpost.com/opinions/2021/…

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More from @MonicaGandhi9

Monica Gandhi MD, MPH Profile picture
31 Oct
How other countries can teach the Bay Area about the COVID-19 endgame - Think important for California to keep looking at Denmark (opened up completely on Sept 10 at same vax rate) for their trends
sfchronicle.com/opinion/openfo…
If you look at Denmark's graphics, you will see cases going up but deaths staying low - in fact, please go to this website & put your cursor on y-axis (0-4 per day since opened)
graphics.reuters.com/world-coronavi… Image
So, keep on looking at hospitalizations as cases rising in highly vaccinated regions are not the best indictor of the high protection of the vaccines (can be simplified into T cells/B cells - high protection- vs antibodies - which fade; see pinned tweet) Image
Read 6 tweets
Monica Gandhi MD, MPH Profile picture
31 Oct
ENDEMICITY: Singapore also makes announcement it will abandon COVID-zero strategy leaving only China currently pursuing this strategy worldwide. Vaccines have massively decoupled cases from hospitalizations & older patients should be boosted & protected
npr.org/transcripts/10…
Somehow cases in light of vaccinations have led some to think vaccines don't work. It is the amazing ability of the vaccines to defang the virus that show they work.
We can see different states in the US also pursuing COVID zero too but it is the duty of public health to attend to all ills of society, people didn't come in because of COVID fear " we're seeing more acute cases than we were pre-pandemic"
medscape.com/viewarticle/96…
Read 4 tweets
Monica Gandhi MD, MPH Profile picture
30 Oct
OFF-RAMPS FOR MASKS IN SCHOOLS: @nytimes @JessGrose (I & others interviewed) on off-ramps for masks in schools. I suggest mask optional (people can still wear of course!) 8 weeks after 5-11 can get vax. "Intellectually honest" to discuss downsides to kids wearing masks
My co-author on mask article @linseymarr: "The vaccine should change things for us, and we don’t want kids to wear masks in school indefinitely Image
Kid masking has been one of the most controversial issues in our country. I think inside masking very important until we got to metric or child vax availability. Don't think governments can impose mask mandates for other pathogens like colds but will be everyone's choice Image
Read 4 tweets
Monica Gandhi MD, MPH Profile picture
29 Oct
DO YOU NEED 3RD SHOT IF INFECTED AFTER VAX?: We definitely know exposure after vaccination (like in the Provincetown outbreak) stimulates both antibodies/T cells to the variant you see. Exposure after vax will happen (not deliberately); would not boost with 3rd dose if happens
Your B cells will actually adapt antibodies if they see virus again to that variant so those in the P-town outbreak study above had delta variant-specific antibodies (including those in nose, IgA, and blood/respiratory tract, IgG)
P-town study above shows BOTH antibodies and CD4 cells (these are T cells) increase with the exposure and the antibodies are directed against not just the spike protein but other parts of the virus Image
Read 6 tweets
Monica Gandhi MD, MPH Profile picture
28 Oct
MISTAKEN MESSAGES: Think these 2 messages continue to decrease confidence in the vaccines: 1) Vaccines don't reduce transmission: Untrue. CDC data shows 6x less likely to get infected if vax'd to begin with; 2) Boosters needed so didn't work but 2-dose vax holding up really well
Mistaken message #1: Here is thread on why you are less likely to transmit if vaccinated (which is compelling reason that vaccines protect you and others)
Mistaken message #2: Nice article today about how well the original vax holding up to protect against severe disease. Yes, after President Biden made announcement re: boosters, FDA/CDC had to address so said boost J&J & >65 but look how well working
abcnews.go.com/Health/booster…
Read 4 tweets
Monica Gandhi MD, MPH Profile picture
28 Oct
Right, with 2/3 of parents either on the fence or seeing no reason to vaccinate their child, I would not try to motivate in any way but with optimism. I am very depressed by our approach.
There is nothing COVID minimizing to say that children are much less at risk of severe disease than adults, especially older. This is a blessing. However, since the risk is not zero, I recommend adults vaccinate their children if not naturally infected to 1) make it as close
to zero as possible (I would do this if I had a magic wand to ensure nothing ill befalls my child); 2) protect others (yes, our society is less vaccinated than others); 3) of course have normalcy. We have asked young people (college students) to protect older this whole pandemic
Read 5 tweets

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