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Billy Bostickson 🏴👁&👁 🆓 Profile picture
@BillyBostickson
Oct 30, 2021 • 30 tweets • 13 min read • Read on X
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1. Ariadne's Thread - SARS Vaccines

Collection of SARS Vaccine papers for Maze addicts

How was the Minotaur born?
2. Immunogenicity difference between the SARS coronavirus and the bat SARS-like coronavirus spike (S) proteins
Peng Zhou,Zhenggang Han,Lin-Fa Wang, Zhengli Shi

ncbi.nlm.nih.gov/labs/pmc/artic…
3. Immunogenicity of the spike glycoprotein of Bat SARS-like coronavirus

Yu-xuan Hou,Cheng Peng, Zheng-gang Han, Peng Zhou, Ji-guo Chen, Zheng-li Shi

1https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7090579/
4. Following the thread
5. Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

ncbi.nlm.nih.gov/labs/pmc/artic…
6. Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

ncbi.nlm.nih.gov/labs/pmc/artic…
7. A 219-mer CHO-Expressing Receptor-Binding Domain of SARS-CoV S Protein Induces Potent Immune Responses and Protective Immunity

ncbi.nlm.nih.gov/labs/pmc/artic…
8. Unravelling the Thread
9. Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

ncbi.nlm.nih.gov/labs/pmc/artic…
10. Vaccine Design for Severe Acute Respiratory Syndrome Coronavirus

liebertpub.com/doi/10.1089/vi…
11. Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

ncbi.nlm.nih.gov/labs/pmc/artic…
12. Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

ncbi.nlm.nih.gov/labs/pmc/artic…
13. Minotaur emerges
14. Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of SARS-CoV Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection

ncbi.nlm.nih.gov/labs/pmc/artic…
15. Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice (WIV, 2010)

ncbi.nlm.nih.gov/labs/pmc/artic…
16. Easy for a Mouse
17. A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

ncbi.nlm.nih.gov/labs/pmc/artic…
For whom does the Bell Toll?

Effects of Toll-Like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c Mice Immunized with UV-Inactivated Severe Acute Respiratory Syndrome-Related Coronavirus Vaccine

ncbi.nlm.nih.gov/labs/pmc/artic…
19. For Ferrets and Monkeys!

Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

ncbi.nlm.nih.gov/labs/pmc/artic…
20. SARS-CoV Spike Proteins Expressed by the Vaccinia Virus Tiantan Strain: Secreted SQ Protein Induces Robust Neutralization Antibody in Mice

liebertpub.com/doi/10.1089/vi…
21. Chimeric Minotaur
22. Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV

ncbi.nlm.nih.gov/labs/pmc/artic…
23. Development of subunit vaccines against severe acute respiratory syndrome
Du, L., He, Y., Jiang, S., Zheng, B.-J.

journals.prous.com/journals/servl…
24. The Shadow
25. Potent neutralization antibody elicited in mice by SARS-associated coronavirus spike protein S1 domain

pubmed.ncbi.nlm.nih.gov/15640862/
27. The expression and antigenicity of a truncated spike-nucleocapsid fusion protein of severe acute respiratory syndrome-associated coronavirus

ncbi.nlm.nih.gov/labs/pmc/artic…
28. Truncated Recombinations, a Mouse's Nightmare
29. More
1. Studies of SARS vaccines
hkmj.org/abstracts/v14n…
2. Animal coronavirus vaccines: lessons for SARS
pubmed.ncbi.nlm.nih.gov/15742624/
3. SARS Vaccine Development
ncbi.nlm.nih.gov/labs/pmc/artic…
4.Vaccine Design for SARS
liebertpub.com/doi/10.1089/vi…
5. SARS Vaccination
cmi.ustc.edu.cn/1/3/193.pdf
30. From SARS 1 to SARS 2

A Review on SARS-CoV-2-Induced Neuroinflammation, Neurodevelopmental Complications, and Recent Updates on the Vaccine Development

ncbi.nlm.nih.gov/labs/pmc/artic…
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More from @BillyBostickson

Billy Bostickson 🏴👁&👁 🆓 Profile picture
Apr 29
1. Ducks and DURC in China (2026)

This is GOF research via experimental adaptation increasing pathogenicity which is DURC because it involves a listed high-risk pathogen and increases virulence via serial passage in a key reservoir host. i.e. DUCKS!

mdpi.com/1999-4915/18/5…
2. Lethal Duck Killer

The Jiangsu researchers deliberately turned a relatively mild H5N6 avian influenza virus into a highly lethal killer of ducks through repeated serial passage in duck cells and live mallard ducks.
3. Good opportunity to boost my Video from 2013!

What originally caused zero deaths in mallards was rapidly adapted into a strain causing up to 100% mortality, massive viral replication in organs, and severe disease..

Ping The Chinese Duck's Nightmare

Read 11 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Mar 31
1. Here is yet another example of twisted biased agenda driven science

(Whether or not you are in favor of vaping)

theguardian.com/australia-news…

Clearly the pathetic excuses for science journalists at the Guardian & other MSM failed to fact check the paper:

sciencemediacentre.org/expert-reactio…
2. Prof Peter Shields, Professor of Medical Oncology at Ohio State University

“This paper does not add anything we do not already know, but selectively cites studies (and omits many others that refute the authors statements throughout) that leads the reader down the wrong path"
3. Prof Peter Shields (2)

“None of their mechanistic studies (selectively cited) has been validated as actual risk predictors in people, and the authors failure to recognize that leads to harmful conclusions."
Read 25 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Mar 12
Critical Examination of 3 Related Studies on SARS-CoV-2 Origins


My latest paper, a pleasantly vicious critique, reveals exactly how the zoonati clique try to bamboozle gullible journalists and scientists to drive their biased narrative of natural originresearchgate.net/publication/40…
2. This core interpretive move by the authors, from failure to detect a shift in selection pressure to claiming strong evidence of “no adaptation being required”, exemplifies the pernicious absence of evidence-based reasoning so characteristic of their tedious papers.
3. Yet, a small cluster of publications from a recurring group of agenda driven authors continues to exert disproportionate and malign influence on the debate over the origins of SARS-COV-2.
Read 10 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Mar 11
1. A truly stunning example of what is called an "ad hoc hypothesis", i.e. a secondary hypothesis added to a theory specifically to save it from being falsified when evidence for its original version is missing or contradictory.

(in this case, the long lost intermediate host)
2. They used a modeling framework called RELAX to claim that viruses like SARSCoV2 may already have the ability to infect humans whilst in their natural reservoir, meaning an intermediate host or long-term adaptation wouldn't leave the evolutionary footprints previously expected.
3. A classic post hoc justification for the absence of physical evidence by grant stuffed criminals, in short:

I couldn't find the evidence I said was required, so I've invented a theory that explains why the evidence I failed to find was never actually needed in the first place
Read 13 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Mar 9
The Havana Cat is finally out of the CIA Bag!

The 60 Minutes investigation into Havana Syndrome

youtube.com/watch?v=Ixdsvi…

Transcript

Havana Syndrome investigation is "a massive CIA cover-up"

cbsnews.com/news/us-milita…

h/t @a_kruschke x.com/BillyBostickso…
"The weapon is real. The injuries are real. The cover-up lasted a decade"

So-called "Secret Labs" 😆

1. NAMRU-Dayton (rats & sheep) GL-6000 "Kraken" Disorientation Device (vestibular disruptions & vertigo). ENVIRONMENTAL HEALTH EFFECTS LAB. Director: Dr. Karen Mumy
wpafb.af.mil/Units/Naval-Me…

2. Wayne University (ferrets)

peta.org/wp-content/upl…
Read 11 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Nov 14, 2025
🧵Long live the lab-leak hypothesis!

1. The long awaited 293 questions for Dr. Ralph Baric have finally been completed and shared! Long live the quest for truth! You are hereby invited to read the sharpest, most lethal 293-question dossier ever built.

researchgate.net/publication/39…
🧵Long live the quest for truth!

2. When that day finally comes & Baric raises his right hand, every word in there will be waiting for him


@RandPaul @RandPaulReview @TulsiGabbard
@SenJoniErnst @R_H_Ebright @jhas5 @ydeigin @gdemaneuf @mentju4 @emilyakopphsgac.senate.gov/media/reps/cha…
@RandPaul @RandPaulReview @TulsiGabbard @SenJoniErnst @R_H_Ebright @jhas5 @ydeigin @gdemaneuf @mentju4 @emilyakopp 🧵3. Watch the video explainer here

Courtesy of Google Notebook LM

vimeo.com/1136899679
Read 6 tweets

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