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Billy Bostickson 🏴👁&👁 🆓 Profile picture
@BillyBostickson
Oct 30, 2021 • 30 tweets • 13 min read • Read on X
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1. Ariadne's Thread - SARS Vaccines

Collection of SARS Vaccine papers for Maze addicts

How was the Minotaur born?
2. Immunogenicity difference between the SARS coronavirus and the bat SARS-like coronavirus spike (S) proteins
Peng Zhou,Zhenggang Han,Lin-Fa Wang, Zhengli Shi

ncbi.nlm.nih.gov/labs/pmc/artic…
3. Immunogenicity of the spike glycoprotein of Bat SARS-like coronavirus

Yu-xuan Hou,Cheng Peng, Zheng-gang Han, Peng Zhou, Ji-guo Chen, Zheng-li Shi

1https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7090579/
4. Following the thread
5. Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

ncbi.nlm.nih.gov/labs/pmc/artic…
6. Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

ncbi.nlm.nih.gov/labs/pmc/artic…
7. A 219-mer CHO-Expressing Receptor-Binding Domain of SARS-CoV S Protein Induces Potent Immune Responses and Protective Immunity

ncbi.nlm.nih.gov/labs/pmc/artic…
8. Unravelling the Thread
9. Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

ncbi.nlm.nih.gov/labs/pmc/artic…
10. Vaccine Design for Severe Acute Respiratory Syndrome Coronavirus

liebertpub.com/doi/10.1089/vi…
11. Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

ncbi.nlm.nih.gov/labs/pmc/artic…
12. Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

ncbi.nlm.nih.gov/labs/pmc/artic…
13. Minotaur emerges
14. Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of SARS-CoV Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection

ncbi.nlm.nih.gov/labs/pmc/artic…
15. Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice (WIV, 2010)

ncbi.nlm.nih.gov/labs/pmc/artic…
16. Easy for a Mouse
17. A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

ncbi.nlm.nih.gov/labs/pmc/artic…
For whom does the Bell Toll?

Effects of Toll-Like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c Mice Immunized with UV-Inactivated Severe Acute Respiratory Syndrome-Related Coronavirus Vaccine

ncbi.nlm.nih.gov/labs/pmc/artic…
19. For Ferrets and Monkeys!

Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

ncbi.nlm.nih.gov/labs/pmc/artic…
20. SARS-CoV Spike Proteins Expressed by the Vaccinia Virus Tiantan Strain: Secreted SQ Protein Induces Robust Neutralization Antibody in Mice

liebertpub.com/doi/10.1089/vi…
21. Chimeric Minotaur
22. Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV

ncbi.nlm.nih.gov/labs/pmc/artic…
23. Development of subunit vaccines against severe acute respiratory syndrome
Du, L., He, Y., Jiang, S., Zheng, B.-J.

journals.prous.com/journals/servl…
24. The Shadow
25. Potent neutralization antibody elicited in mice by SARS-associated coronavirus spike protein S1 domain

pubmed.ncbi.nlm.nih.gov/15640862/
27. The expression and antigenicity of a truncated spike-nucleocapsid fusion protein of severe acute respiratory syndrome-associated coronavirus

ncbi.nlm.nih.gov/labs/pmc/artic…
28. Truncated Recombinations, a Mouse's Nightmare
29. More
1. Studies of SARS vaccines
hkmj.org/abstracts/v14n…
2. Animal coronavirus vaccines: lessons for SARS
pubmed.ncbi.nlm.nih.gov/15742624/
3. SARS Vaccine Development
ncbi.nlm.nih.gov/labs/pmc/artic…
4.Vaccine Design for SARS
liebertpub.com/doi/10.1089/vi…
5. SARS Vaccination
cmi.ustc.edu.cn/1/3/193.pdf
30. From SARS 1 to SARS 2

A Review on SARS-CoV-2-Induced Neuroinflammation, Neurodevelopmental Complications, and Recent Updates on the Vaccine Development

ncbi.nlm.nih.gov/labs/pmc/artic…
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More from @BillyBostickson

Billy Bostickson 🏴👁&👁 🆓 Profile picture
Jul 29
If you see a snake today..🐍

1. Based on the Parsi calendar conversion and the text of the Persian Mar-Nāmeh (THE BOOK FOR TAKING OMENS FROM SNAKES), seeing a snake today means you should not look at it, otherwise you will soon have a cause to be sorry.
2. Rule 7 cruelly says:

"If you see a snake on the day of Merdad (Amerdid) do not look at it, (or otherwise) you will soon have a cause to be sorry"

According to the Parsees, today is Roj Amardad (also spelled Merdad or Amerdāt).
3. If you see it, how can you not look at it?

The Book for Taking Omens from Snakes (30 Nov 1892)

By President-Surgeon-Major G. Waters.

"The custom of taking omens from snakes seems to be
very ancient. The people of antiquity associated with the snake various peculiar ideas"
Read 23 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Jul 28
1. The morning breaks on human backs

Across the centuries & the tracks,
Where bone & muscle give their all,
To answer to the master's call.
And in the pocket, pouch, or hand,
A secret comfort rules the land.
A cheap escape from sweat & pain,
To dull the mind or spike the brain.
2. In London’s fog, the engine roars

And laborers crowd through palace doors,
To drown the shift in burning gin.
While in the slums, for just a penny,
The laudanum drops are shared by many,
To soothe the cough, the cramp, the tear,
And quiet the children crying there.
3. Across the sea, the jungle steams

Where coolies chased their broken dreams.
The shovel bites, the fever burns,
Until the evening sun returns.
Then in the bunkhouse, dark & small,
Sweet smoke rises on the wall;
The opium pipe is lit & blessed,
A pain-free haze, a perfect rest!
Read 11 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Jul 27
1. Summarizing "Fauci's prequel" is not difficult!

Tony's Diary: The Prequel via @SenRandPaul

paul.senate.gov/wp-content/upl… x.com/BillyBostickso…
2. @_whitneywebb revealed just about everything

@_whitneywebb 3. Another short summary from 2020

Read 6 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Jul 26
1. A shout out to all the clever and free apps that we have used for 6 years, without which we would be still in the dark

@threadreaderapp @ProtonMail @archiveis @OpenAlex_org @TheLensOrg @Gemini_Notebook @TranslateYandex @TransIateGoogIe @ResearchGate @ZENODO_ORG @arxiv @github
2. More apps used

@YouTube
@Vimeo
@rumblevideo
Google Patents
@waybackmachine
Justpasteit
@googledrive
@Gemini
@grok

Some Journals

@CellPressNews
@JAMA_current
@Nature
@NEJM
@PLOS
@embojournal

@VirologyJ
@biorxivpreprint
@medrxivpreprintpubmed.ncbi.nlm.nih.gov
@YouTube @Vimeo @rumblevideo @waybackmachine @googledrive @Gemini @grok @CellPressNews @JAMA_current @Nature @NEJM @PLOS @embojournal @VirologyJ @biorxivpreprint @medrxivpreprint 3. One big one I forgot...

@X

That made a vast difference, helping us coordinate our work through chat groups and share our work and keep the public and journalists and U.S. government organizations and commissions informed of the latest updates.
Read 4 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Jul 15
1. Ball, Hung, Drawn and Quartered for Truth

Did ye sing, John Ball,
as they pulled you apart?
A poet speaking for us all
from England’s tattered heart.
What a price, John Ball,
for singing to us all.
When hope came as a crime
in simple rhythm and rhyme.
2. He who sings a blackbird’s song
to a starved & battered throng
with a message to stand strong
would never last long.
So we’ll sing to John Ball
for the helpless & hopeless,
the voiceless, forgotten,
buried beneath the mansions
of Lords; misbegotten
mortar, stones & chandeliers
3. the scarlet grave goods
of England’s preening peers.
We’ll sing in simple rhymes
and hope for better times,
when those barons’ grandchildren,
so viscous, reptilian,
are thrown from their seat
in ignominious defeat.
Read 8 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Jul 12
🧵Explanation Thread

Here is my attempt at a simple summary of what @JasperFarlake & @dr_louwen claim (July 2026)

1. In early 2020, Chinese scientists published the first big paper on the COVID virus using fluid samples taken from patients’ lungs in Wuhan in December 2019.
2. They uploaded the raw sequencing data to public databases so others could check their work, which is great.



@JasperFarlake & @dr_louwen went back & carefully re-examined that raw data

They say they found several strange things that don’t look right.zenodo.org/records/213119…
@JasperFarlake @dr_louwen 3. You can see their findings in the readme.md text which you can see if you download their zip file and extract it.

or here directly on their @github repository

github.com/jasper-cmyk/PR…
Read 27 tweets

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