Abdulla A. Damluji, MD, PhD Profile picture
Nov 5, 2021 20 tweets 18 min read Read on X
Cardiac Arrest and Cardiogenic Shock

There is a societal paper on this in the works too!

Very important work!

@Babar_Basir @venumenon10

#TCT2021 @TCTMD
Methylprednisone - ? not helpful

Advanced reperfusion strategies - small trial

#TCT2021
SCAI Shock Classification

Milrinone vs Dobutamine - no difference

Gaps in pressers in CICU setting: pressers and antiplatelets

@seanvandiepen @JasonKatzMD

#TCT2021
Invasive hemodynamics monitoring

MCS

Unloading

#TCT2021
Shock Teams - CICU @JACCJournals

3-axis model

HF readmission in shock pt

Excellent @Babar_Basir

#TCT2021

@SandeepNathanMD excellent session
***Multi-vessel PCI in Shock***

First side of the coin

Multivessel PCI should not be performed in shock ??

Culprit Shock: Culprit only

NNT = 12

@thiele_holger

#TCT2021
European guidelines

Long term outcomes

STEM pts?
Culprit lesion only PCI and followed by stage PCI in shock
Multivessel PCI in Shock is Way to Go

ESC Guidelines

CI cross in culprit cross at one year?

Metaanalysis - may be there is benefit?

But there is increased risk in renal failure

Culprit is open label - procedural differences?

@BillONeillMD

#TCT2021
NCSI -

77% improved outcomes with support

Culprit vs NCSI

#TCT2021
Conclusion - too nuanced to tell?

#TCT2021
Decisions to use what device in cardiogenic shock

@SandeepNathanMD
Trials and registry data

Impella vs balloon pump
Impella CP in AMI Shock?

#TCT2021
The Pro Case?

Impella CP as first line in shock

Goal in AMI Shock - improved supply/demand

Hemodynamic Effect of IABP, pLVAD, and ECMO

#TCT2021
IABP in AMI-CS

The longer patients linger? the more likely they die...@behnam_tehrani

#TCT2021
Impella Data

Reducing cardiac work

NCSI data @Babar_Basir
Shock teams in patients from the critical care cardiology network @ShashankSinhaMD
Escalation of Device Therapies

- ECMO + Impella (facilitating LV recovery?)

All good, but we need clinical trials in this space.

So far it is hard to argue with @SandeepNathanMD
Excellent session and great speakers @BinitaShahMD @NavinKapur4

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More from @DrDamluji

Jul 21
Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy: @NEJM

🥸 There are many parallels between ischemic strokes and ACS Mx

😱Summary and have a nice Sunday

👇👇👇 Image
🥸 1️⃣ Intravenous thrombolytic agents, such as alteplase, are recommended for eligible patients to be administered within 4.5 hours after the onset of an acute ischemic stroke to maximize the chances of recovery.
🥸 2️⃣ Tenecteplase, a genetically modified form of human tissue plasminogen activator, has been shown to be noninferior to alteplase for the treatment of ischemic stroke.
Read 22 tweets
Mar 23
Ticagrelor or Clopidogrel Monotherapy vs Dual Antiplatelet Therapy After Percutaneous Coronary InterventionA Systematic Review and Patient-Level Meta-Analysis: @JAMACardio

🥸 Good morning: more on SAPT monotherapy vs DAPT

😱Summary

👇👇👇 Image
1.🥸 Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is standard post-PCI to minimize ischemic events, but it increases bleeding risk. Emerging studies prompt a reassessment.

😱 Mainly, in high risk groups: older adults.
2. 🥸 Short DAPT durations followed by P2Y12 inhibitor monotherapy have shown promising reductions in bleeding but raised concerns re ischemic risks in high-risk patients.
Read 13 tweets
Mar 14
Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Left Main Disease With or Without Diabetes: Findings From a Pooled Analysis of 4 Randomized Clinical Trials: @CircAHA

🥸wow: more on left main+diabetes: PCI vs CABG!

😱 Summary

👇👇👇 Image
1/ 🥸 Left main coronary artery disease and diabetes are associated with substantial cardiovascular morbidity and mortality.
2/ 🥸 Yet, long-term outcomes for patients with left main disease and diabetes undergoing PCI compared with CABG remain unclear.
Read 22 tweets
Dec 3, 2023
Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society: @CircAHA

🥸Great work: @AHA_Research @AHA_AcuteCVCare

😱Let's summarize: Happy Sunday :)

👇👇👇 Image
1/🥸 Cardiac Arrest Prevalence: Over 600,000 individuals in the US experience cardiac arrest annually.

😱This is a significant public health problem.
2/ 🥸 Worldwide Incidence: Globally, cardiac arrest occurs in 30 to 97 individuals per 100,000 population.
Read 21 tweets
Nov 12, 2023
Great #AHA23 so far: @AHA_Research

🥸8 Trials: 8 take aways below

Read the read👇👇

1/ATRESIA:

Patients with subclinical atrial fibrillation can benefit from apixaban to reduce the risk of stroke and systemic thromboembolism. Image
2/CARDIA-SSBP:

🥸The decline in SBP with a low-sodium diet was independent of hypertension status and anti-hypertensive medication use, consistent across subgroups, and did not result in excess adverse Image
3/ CRHCP:

🥸Intensive BP lowering (target BP < 130/80 mm Hg) significantly reduced risk of all-cause dementia among patients with hypertension, supporting the use of intensive hypertension treatment to reduce the burden of dementia.

😱 @cardskrish Image
Read 11 tweets
Nov 11, 2023
Semaglutide and Cardiovascular Outcomes
in Obesity without Diabetes: @NEJM

The select trial: #AHA23

🥸Wow! @AHA_Research

😱Now on the stage in main event

😱Let's get the highlights

👇👇👇 Image
1.🥸 GLP-1 receptor agonists are known for cardiovascular benefits in type 2 diabetes.
2.🥸 The SELECT trial tested semaglutide, a potent member of GLP-1 class of drugs, for cardiovascular risk in overweight individuals without diabetes history.
Read 19 tweets

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