Abdulla A. Damluji, MD, PhD Profile picture
• Mesopotamian • Former competitive swimmer • Interventional cardiologist: #Aging • Dean’s Scholar EMBA: @NYUStern • Every heart vibrates to that iron string!
Nov 1 17 tweets 2 min read
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation: @NEJM

🥸 TRISCEND II Trial - #TCT2024

😱 Summary

👇👇👇 Image 🥸 1️⃣ Severe tricuspid regurgitation leads to high symptom burden and increases risk of mortality.
Oct 28 21 tweets 3 min read
Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis: @NEJM

🥸 I was at #TCT2024 all day - just got to a desk @TCTMD

😱 Summary of EARLY TAVR trial

👇👇👇 Image 🥸1️⃣ The EARLY TAVR trial focused on patients with asymptomatic severe aortic stenosis and preserved LV function to see if early transcatheter aortic-valve replacement (TAVR) outperformed standard surveillance.
Oct 20 33 tweets 4 min read
Intra-operative and post-operative management of conduits for coronary artery bypass grafting: @ESC_Journals

🥸 Management of CABG conduits: Congratulations to the authors and ESC.

😱 Will try to keep it <30 points

👇👇👇👇 Image 🥸1️⃣ Coronary artery bypass grafting (CABG) relies on conduit integrity for long-term success. Preserving the structural and functional quality of conduits during intra- and post-operative management is critical to ensuring graft patency.
Oct 10 22 tweets 3 min read
Sudden cardiac death after myocardial infarction: @ESC_Journals

🥸 Of the 140,204 post MI patients, 1,326 (0.945%) developed sudden cardiac death.

😱 Can we predict those who developed sudden death with clinical variables including LVEF and MRI data?

👇👇👇 Image 🥸 1️⃣ Sudden cardiac death (SCD) causes about 20% of deaths, and post myocardial infarction survivors with low LVEF are at higher risk because of life-threatening ventricular arrhythmias.
Oct 8 31 tweets 3 min read
SCAI Expert Consensus Statement on the Management of Patients With STEMI Referred for Primary PCI: @MyJSCAI

🥸 Nice documents on STEMI and primary PCI: congratulations to authors and @SCAI

😱 Here are few recommendations from the document

👇👇👇 Image 🥸1️⃣ Cardiac Catheterization Laboratory (CCL) Equipment: Ensure availability of plaque modification devices, guide extension devices, and intracoronary imaging tools for effective STEMI management in the catheterization lab.
Sep 4 19 tweets 3 min read
Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up: @TheLancet

🥸 "The use of MCS should be restricted to certain patients only" ~ @thiele_holger

😱 Summary

👇👇 Image 🥸 1️⃣ Cardiogenic shock still has a high mortality rate, around 40-50%, despite medical advances. For AMI-related cariogenic shock, immediate revascularization is the only proven life-saving treatment.
Jul 21 22 tweets 4 min read
Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy: @NEJM

🥸 There are many parallels between ischemic strokes and ACS Mx

😱Summary and have a nice Sunday

👇👇👇 Image 🥸 1️⃣ Intravenous thrombolytic agents, such as alteplase, are recommended for eligible patients to be administered within 4.5 hours after the onset of an acute ischemic stroke to maximize the chances of recovery.
Mar 23 13 tweets 3 min read
Ticagrelor or Clopidogrel Monotherapy vs Dual Antiplatelet Therapy After Percutaneous Coronary InterventionA Systematic Review and Patient-Level Meta-Analysis: @JAMACardio

🥸 Good morning: more on SAPT monotherapy vs DAPT

😱Summary

👇👇👇 Image 1.🥸 Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is standard post-PCI to minimize ischemic events, but it increases bleeding risk. Emerging studies prompt a reassessment.

😱 Mainly, in high risk groups: older adults.
Mar 14 22 tweets 4 min read
Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Left Main Disease With or Without Diabetes: Findings From a Pooled Analysis of 4 Randomized Clinical Trials: @CircAHA

🥸wow: more on left main+diabetes: PCI vs CABG!

😱 Summary

👇👇👇 Image 1/ 🥸 Left main coronary artery disease and diabetes are associated with substantial cardiovascular morbidity and mortality.
Dec 3, 2023 21 tweets 3 min read
Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society: @CircAHA

🥸Great work: @AHA_Research @AHA_AcuteCVCare

😱Let's summarize: Happy Sunday :)

👇👇👇 Image 1/🥸 Cardiac Arrest Prevalence: Over 600,000 individuals in the US experience cardiac arrest annually.

😱This is a significant public health problem.
Nov 12, 2023 11 tweets 3 min read
Great #AHA23 so far: @AHA_Research

🥸8 Trials: 8 take aways below

Read the read👇👇

1/ATRESIA:

Patients with subclinical atrial fibrillation can benefit from apixaban to reduce the risk of stroke and systemic thromboembolism. Image 2/CARDIA-SSBP:

🥸The decline in SBP with a low-sodium diet was independent of hypertension status and anti-hypertensive medication use, consistent across subgroups, and did not result in excess adverse Image
Nov 11, 2023 19 tweets 3 min read
Semaglutide and Cardiovascular Outcomes
in Obesity without Diabetes: @NEJM

The select trial: #AHA23

🥸Wow! @AHA_Research

😱Now on the stage in main event

😱Let's get the highlights

👇👇👇 Image 1.🥸 GLP-1 receptor agonists are known for cardiovascular benefits in type 2 diabetes.
Oct 22, 2023 28 tweets 3 min read
Frailty-Guided Management of Cardiovascular Disease— From Clinical Trials to Clinical Practice: @JAMACardio

🥸More on this in @JACCJournals soon...

Discussion below -

👇👇 Image 🥸1. Frailty is a reduced physiological reserve and increased vulnerability to stressors.

😱 Important for CVD Management and Interventional Cardiology Procedures.
Oct 8, 2023 32 tweets 4 min read
Nondental Invasive Procedures and Risk of Infective Endocarditis: Time for a Revisit: A Science Advisory from the @American_Heart: @CircAHA

😱Can you please keep the summary less than 30 points?

🥸 I will try, but I do not want to.

😱🔫

Late Sunday summary below

👇👇👇 Image 1️⃣🥸😱 Infective endocarditis (IE) poses a risk of severe complications, and warrants prevention in high-risk patients.
Sep 18, 2023 36 tweets 5 min read
Impact of Complete Revascularization in the ISCHEMIA Trial: @JACCJournals

How do you interpret the results of this ischemia sub-study? The devil is in the detail. 😱

Good morning: 🥸

Below 👇👇 Image 🥸1. In the ISCHEMIA study, 43.4% and 58.4% of revascularization procedures met the criteria for Achieved Complete Revascularization and Functional Complete Revascularization, respectively.
Jul 7, 2023 26 tweets 4 min read
P2Y12 Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events: @JACCJournals

*** Great - this is what @AHAScience recommended for older higher risk patients: @MichaelGNanna

25-point summary in am report: (they are short sentences 😱)

👇👇👇 1/25 🥸 This meta-analysis of randomized controlled trials involved 24,325 participants with established coronary artery disease (CAD). Most received modern pharmaco-invasive treatments.
Jun 14, 2023 17 tweets 4 min read
Association of Beta-Blocker Therapy With Cardiovascular Outcomes in Patients With Stable Ischemic Heart Disease: @JACCJournals

My friend @MichaelGNanna is studying the effects of beta blockers and calcium channel blockers in older pts with SIHD: @PCORI

15-point summary 👇👇👇 Image 1/15 🥸 In a study of patients with stable coronary artery disease, beta-blocker therapy showed an 8% relative and 1.8% absolute risk reduction in all-cause mortality and hospitalization for heart failure or myocardial infarction over 5 years. Image
Jun 13, 2023 21 tweets 3 min read
Bioprosthetic Valve Remodeling in Nonfracturable Surgical Valves Impact on THV Expansion and Hydrodynamic Performance: @JACCJournals

Abbreviations

BVR = bioprosthetic valve remodeling
VIV = valve in valve
SHV = nonfracturable heart valve

Summary on this nice paper

👇👇🥸 Image 1/20 🥸 this study found that in Trifecta GT and Hancock II SHVs, BVR brought about limited improvement in THV expansion, largely dependent on the type of surgical valve and THV.
May 15, 2023 46 tweets 10 min read
Sarcopenia and Cardiovascular Diseases: @CircAHA

From the Geriatric Cardiology Leadership Council: @ACCinTouch

Main congratulations to @Dr_Alfaraidy: a board certified geriatrician and a cardiology fellow - she is amazing AND the best: @ParagGoyalMD 👏

Summary👇👇👇 Image 1/ 🚨 Sarcopenia is the loss of muscle strength, mass & function, worsened by chronic illness like CVD, kidney disease, & cancer 😷🩺
May 11, 2023 21 tweets 7 min read
Hierarchical Development of Physical Frailty and Cognitive Impairment and Their Association With Incident Cardiovascular Disease: @JACCJournals @NailaIjaz_MD

This analysis evaluated the timing of developing cognitive impairment & frailty in pts at risk for CAD!!

Summary 👇👇 Image 1/ In this @JACCJournals study, we examined the patterns of frailty and cognitive impairment (CI) development and their associations with cardiovascular outcomes in older adults without prior known coronary artery disease (CAD) during a 5-year follow-up. 🧠❤️

#NHATS
May 10, 2023 42 tweets 7 min read
Epidemiology of Diabetes and Atherosclerotic Cardiovascular Disease Among Asian American Adults: Implications, Management, and Future Directions: A Scientific Statement From the American Heart Association: @CircAHA

Nice statement on high risk group

Summary 👇👇👇 Image 1/ 🌏 Asian Americans (AsA) are the fastest growing ethnic group in the US 🇺🇸. They face high risks of Type 2 diabetes (T2D) & atherosclerotic cardiovascular disease (ASCVD) - major risks.