•Mesopotamian •Former competitive swimmer •Interventional cardiologist: #Aging •Dean’s Scholar, Finance @NYUStern •Every heart vibrates to that iron string!
🥸 1️⃣ Obesity drives heart failure with preserved ejection fraction (HFpEF) through systemic inflammation and visceral adiposity. Tirzepatide, a dual GIP and GLP-1 receptor agonist, offers weight loss and potential cardiovascular benefits.
🥸 1️⃣ Oral anticoagulation is standard after atrial fibrillation (AF) ablation for stroke prevention but comes with bleeding risks and patient burdens. Left atrial appendage closure (LAAC) offers an alternative, but data comparing these strategies post-ablation have been limited.
🥸 1️⃣ Aldosterone levels predict worse outcomes after myocardial infarction (MI). 
🥸 1️⃣ Severe tricuspid regurgitation leads to high symptom burden and increases risk of mortality.
🥸1️⃣ The EARLY TAVR trial focused on patients with asymptomatic severe aortic stenosis and preserved LV function to see if early transcatheter aortic-valve replacement (TAVR) outperformed standard surveillance.
🥸1️⃣ Coronary artery bypass grafting (CABG) relies on conduit integrity for long-term success. Preserving the structural and functional quality of conduits during intra- and post-operative management is critical to ensuring graft patency.
🥸 1️⃣ Sudden cardiac death (SCD) causes about 20% of deaths, and post myocardial infarction survivors with low LVEF are at higher risk because of life-threatening ventricular arrhythmias.
🥸1️⃣ Cardiac Catheterization Laboratory (CCL) Equipment: Ensure availability of plaque modification devices, guide extension devices, and intracoronary imaging tools for effective STEMI management in the catheterization lab.
🥸 1️⃣ Cardiogenic shock still has a high mortality rate, around 40-50%, despite medical advances. For AMI-related cariogenic shock, immediate revascularization is the only proven life-saving treatment.
🥸 1️⃣ Intravenous thrombolytic agents, such as alteplase, are recommended for eligible patients to be administered within 4.5 hours after the onset of an acute ischemic stroke to maximize the chances of recovery.
1.🥸 Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is standard post-PCI to minimize ischemic events, but it increases bleeding risk. Emerging studies prompt a reassessment.
1/ 🥸 Left main coronary artery disease and diabetes are associated with substantial cardiovascular morbidity and mortality.
1/🥸 Cardiac Arrest Prevalence: Over 600,000 individuals in the US experience cardiac arrest annually. 
2/CARDIA-SSBP: 
1.🥸 GLP-1 receptor agonists are known for cardiovascular benefits in type 2 diabetes.
🥸1. Frailty is a reduced physiological reserve and increased vulnerability to stressors.
1️⃣🥸😱 Infective endocarditis (IE) poses a risk of severe complications, and warrants prevention in high-risk patients.
🥸1. In the ISCHEMIA study, 43.4% and 58.4% of revascularization procedures met the criteria for Achieved Complete Revascularization and Functional Complete Revascularization, respectively.
1/25 🥸 This meta-analysis of randomized controlled trials involved 24,325 participants with established coronary artery disease (CAD). Most received modern pharmaco-invasive treatments.
1/15 🥸 In a study of patients with stable coronary artery disease, beta-blocker therapy showed an 8% relative and 1.8% absolute risk reduction in all-cause mortality and hospitalization for heart failure or myocardial infarction over 5 years. 
1/20 🥸 this study found that in Trifecta GT and Hancock II SHVs, BVR brought about limited improvement in THV expansion, largely dependent on the type of surgical valve and THV.