Thread:

In 1958, my mother was a NYC teacher. Early in the year, she was exposed to a student with Rubella ("German Measles").

Rubella is almost always a very mild illness. Most don't even know they have it. My mother had no symptoms. 1/8

ecdc.europa.eu/en/rubella/fac…
Why do we care about Rubella (sufficient to require vaccination in all states)? Because pregnant women exposed to Rubella in their first trimester have a substantially increased likelihood of having a child w/birth defects/Congenital Rubella Syndrome (CRS) or fetal demise. 2/8
My mother knew she was pregnant and had heightened concern that was proved justified well after the September birth of my sister. It would not be for some time that my parents knew that 1) my sister was PROFOUNDLY deaf & 2) nothing worse had befallen her. 3/8
We don't have precise numbers for the 1958 Rubella outbreak (which typically happened every 6-9 years, though endemic in between), but we know that the 1964-5 outbreak (the last before introduction of a vaccine) led to 20K KNOWN cases of CRS & >2K newborn deaths. 4/8
My sister retired this year after a nearly 40 yr career, having raised 2 beautiful daughters with her (also deaf) husband of 41 yrs. She is a fantastic lip-reader & benefits from technology (facetime & other video calling services, captioning, etc.) & signing. 5/8
This thread is to remind you that we don't always vaccinate children JUST to protect the child (There is no reason to vaccinate children for Rubella except for the excessive and serious risk to pregnant women). 6/8
Thanks to vaccinations, < 10 people get Rubella each year. Current vaccine is 97% effective.

Why do we vaccinate children, if pregnant women can get vaccine on their own? Because the vaccine is NOT 100% effective & people don't always plan well. 7/8

cdc.gov/vaccines/vpd/m…
Public health is about taking measures to protect the community. It does not start with Covid. It will not end with Covid.

Get vaccinated: for yourself; For your family; For your friends; And for those you might never even know or like. 8/8

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More from @thehowie

5 Nov
"Fewer than 1% of patients taking the drug needed to be hospitalized and no one died. In the comparison group, 7% were hospitalized and there were seven deaths."

THIS is a game changer, with caveats:

bostonglobe.com/2021/11/05/bus… via @BostonGlobe
"Treatment began within three to five days of initial symptoms, and lasted for five days."

This means people need to have ACCESS to testing, clinical evaluation and a prescription. (True for Monoclonal antibodies, as well).

In the real world, people often present TOO late.
This is already approved in the UK. This will be reviewed by FDA on November 30 for EUA. fda.gov/news-events/pr…
Read 4 tweets
5 Nov
Incredible investigative journalism on why Africa was seemingly *spared* the worst of COVID.

The answer is not younger pop, more Ivermectin, nor climate.

Answer: Lack of testing and massive cover-up.

Great reporting by @JoeWSJ .

Short thread of his findings:
"At the Kondo graveyard in Dar es Salaam, Tanzania...We used to bury one a week [before the pandemic], but over the past year we have reached 17 a day.”
"Last year, President John Magufuli declared the virus a “satanic myth” propagated by imperialist powers.... ...and labeled those who wore masks unpatriotic.

By this spring, the president was dead, along with 6 other senior politicians..."
Read 10 tweets
30 Oct
CDC quietly released this VERY consummate REVIEW (not new study) of existing evidence about vaccine-acquired & infection acquired immunity.

It is a VERY good summary and everyone should read it.

Key points in this thread. 1/7

cdc.gov/coronavirus/20…
Love that they start with humility. Everyone should feel this way. Most don't.

"New data continue to emerge, and recommendations (the science brief, this webpage, etc.) will be updated periodically, as needed."
2/7
"...fully vaccinated individuals and those previously infected with SARS-CoV-2 each have a low risk of subsequent infection for at least 6 months."

More people need to acknowledge this. 3/7
Read 7 tweets
18 Oct
Yale Update (short thread)
0.15% pos.rate for students (0.17% undergrads⬆️; 0.1% grad students⬇️)
0.25% for faculty staff⬇️

Vaccination rates creep higher.

We are at VERY similar case levels to last year: why should be celebrate? Because we are MUCH closer to normal.
Last year, there were few classes held in-person and those that were held, were near empty. This year, full census in classrooms.
Last year, staff (including most/many faculty) & researchers were primarily WFH. This year, they are back to working on-site, albeit with some accommodations/modifications.
Read 7 tweets
18 Oct
Brief thread:

We have a "rheostat". It works by dialing up and down *some* de-densification, masking, TESTING, & OBVIOUSLY vaccinations, but also boosters at some point.

We can AND SHOULD dial these up when outbreaks present.
It does not mean that we can't have social events, but we need to offset this in other ways.

Wear a mask if you are speaking face to face with someone.
DO NOT hold events in poorly ventilated spaces.

Use AND advocate testing in schools and other settings where spread WILL occur.
Read 6 tweets
12 Oct
Key findings from KFF:

"...91% of Democrats, 85% of independents, and 76% of Republicans, as well as majorities of seniors (84%), who would be most affected by such a provision [favor drug price negotiations by Medicare prior to learning more]"
"...most (84%) of the public, including 3/4 (78%) of Republicans, say the argument in favor – “this is needed because Americans pay higher prices than people in other countries, many can’t afford their prescriptions, & drug company profits are too high” – is convincing."
"...a third (33%) say the argument against – “this would have the government too involved and will lead to fewer new drugs being available in the future” – is convincing. This includes nearly half (45%) of Republicans."
Read 5 tweets

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