Thread by @sailorrooscout

Yes, the vaccines ARE effective against the Delta variant. Yes, you will want both doses for maximum protection. Yes, they’re effective against preventing symptomatic infection, severe disease, AND hospitalization. Several studies have proven this now. Stop the misinformation.

Also, yes, this does include Johnson & Johnson. Why are variants unlikely to FULLY evade vaccine-induced immunity?
•Vaccines are polyclonal (Abs)
•CD8+ T-cells covering 52 epitopes across the spike protein
•CD4+ T-cells covering 23 epitopes across the spike protein

Real-world data out of Ontario, Canada regarding vaccine effectiveness (reduction associated with full vaccination) shows:

•Against Infection: 82.5%
•Against Hospitalization: 91.8%
•Against ICU Admission: 97.2%

Delta is currently the most prevalent variant in Ontario.

Data as of November 13th below. The COVID-19 vaccines are very effective at protecting you from severe illness and hospitalization even in the face of Delta. You can find this information and more here: covid19-sciencetable.ca/ontario-dashbo…

Real-world data out of King County, WA (which includes Seattle) confirms vaccinated individuals are significantly better protected from illness, hospitalization, AND death due to COVID-19 compared to unvaccinated individuals, even as the Delta variant surges through the state.

Over the PAST 30 days, unvaccinated individuals were:
•3X more likely to test positive for COVID-19 (78% of cases)
•12X more likely to be hospitalized for COVID-19 (89% of hospitalizations)
•13X more likely to die of COVID-19 related illness (85% of deaths)

The CDC is posting national data on vaccination status for hospitalization and death due to COVID-19 and it IS stratified by age. In August unvaccinated individuals were:
•6X more likely to test positive for COVID-19
•11X more likely to die of COVID-19 related illness

You can find this information here: covid.cdc.gov/covid-data-tra… (you will need to switch views to see cases vs. deaths). Even in the face of Delta, these vaccines are indeed effective against preventing symptomatic infection, severe disease, hospitalization AND death due to COVID-19.

Published in NEJM. Peer-reviewed. Sound methodology. Delta outbreak in a California detention center (close quartera). Moderna’s vaccine was found to be 84% effective against symptomatic infection. NO hospitalizations among fully vaccinated individuals. nejm.org/doi/full/10.10…

“Results indicate that Moderna’s vaccine was quite effective against SARS-CoV-2 infection during a Delta variant–driven outbreak in this high-risk, congregate setting. Although the effectiveness against infection was substantially lower than that estimated in studies conducted

before the emergence of Delta, protection against symptomatic illness remained robust-an outcome consistent with other recent reports. Notably, full vaccination also conferred additional substantial protection against infection in men with previous confirmed infections.”

Another study published in NEJM. Peer-reviewed. Large sample size (5.4 MILLION). Sound methodology. Pfizer’s and AstraZeneca’s vaccines are highly effective against the Delta variant. Pfizer was found to be 90% effective against COVID-19 related death caused by infection

with Delta, and AstraZeneca’s vaccine was found to be 91% effective against against COVID-19 related death caused by infection with Delta. No deaths had been recorded in those who have been double vaccinated with Moderna’s vaccine in Scotland, according to the data.

You can read more here: nejm.org/doi/full/10.10… and here: thejournal.ie/vaccines-effec…. King County Data can be found here: public.tableau.com/views/COVID_Va…