"For instance, in 2012 we launched the Equivac vaccine, which protects horses from infection and thus prevents transmission of Hendra virus from horses to humans"
26. 2014 - Bat’s immunity may hold key to preventing future Ebola outbreaks (Michele Baker)
If we redirect the immune responses of other species to behave the same way as bats, the high death rate of diseases such as Ebola could be a thing of the past
1. CSIRO helps "developing' China with Biosafety 2. CSIRO teaches Chinese bat virus isolation methodology (Tweet 6) 3. CSIRO - WIV - EHa SARS Paper (2005) Tweet 7 4. PZ, ZLS & LFW at CSIRO 5. PZ & LFW Human & Bat Toll Like Receptors - 2010 (Tweet 11)
34. Summary so far (2)
6. Nipah, Ebola Research and Hendra Vaccine (CSIRO) 7. Bat Immune system & longevity research at CSIRO 8. Bat immune system & longevity research at WIV
9, Live Bat Colony at WIV (and Singapore under LFW)
35. Live Bats at WIV - Myotis Davidii
Why did WIV keep Myotis species bats at WIV in 2017?
Because of their longevity (lifespan up to 37 years)
Growing old, yet staying young: The role of telomeres in bats’ exceptional longevity
36. WIV worked with wild-caught out bred bats and their own colony of live bats (Myotis) as well as splenocytes, tissue and cell lines from these bats.
Primary cells can also harbor latent viruses that can become reactivated during in vitro cultivation when the cells are outside the host and isolated from other components of the immune system that would otherwise control virus replication
39. Repeat (2)
"Cell lines from any species of bat should therefore only be handled under controlled biosafety conditions and thoroughly tested before being used for experimental studies. This is also a limitation when working with wild-caught bats"
In addition to cell lines, there is a need for lab bred bats with known infection status for ex & in vivo experiments. Establishing a wild-caught bat colony is challenging but achievable with sufficient resources to house the bats
This thread began with CSIRO and revealed how CSIRO shared their techniques and research with Chinese Bat Researchers who went on to develop these techniques in China.
Now back to CSIRO - AAHL Lab
51. Beating the world's deadliest viral villains #CSIRO
"During shooting in Thailand, I was shocked by Daszak’s fast & loose with facts, his refusal to acknowledge his conflict of interest,& his denial of his gain-of-function res in collaboration with Wuhan lab"
You guessed right, i hope?
@janeqiuchina
She continued:
"I was equally shocked by Daszak’s constant self-promotion and how effective it was."
@janeqiuchina About the film:
"Blame: Bats, Politics & a Planet Out of Balance"
"Christian Frei seemed entranced by hero worshipping, apparently having lost all sense of objectivity & critical judgment. I felt strongly then, as I do now, that the film was a blatant piece of propaganda"
Bloody Hell, it's worse than even I imagined in my darkest nightmares about #scamdemia.
Time to spend some of this tax money on local electronics, biological, ecological, IT, optical, chemistry, engineering & physics labs run by local amateurs for the benefit of our communities?
Short 🧵on Primer & PCR Test issues (Pangolin Covs)
1. The key issue with pangolins and Pcovs is that:
It was discovered that the standard PCR tests used in 2020, and often still used, failed to actually detect many of the betacoronaviruses generously hosted by the pangolins.
2. Unless
The samples are retested with bespoke primers & more accurate PCR tests available now,
We will not know exactly whIch Pangolin (or bat) coronaviruses were hosted by Pangolins at WIV & elsewhere pre-pandemic.
However, "they" (I will name who they are later) should, and perhaps in the future, may retest the stored samples at WIV, IPB, SCAU AND GIABR, to clarify the question of which coronaviruses were present in their pangolin samples.
2. May have been for research and commercial purposes, but they were caught bang to rights.
"LIU initially stated that he did not know what the materials were and that someone must have put them into his bag"
3. When asked why someone would put them into his bag, LIU stated that he did not know, and that maybe he had accidentally put the materials there. After further questioning, LIU acknowledged that the materials were different strains of the pathogen Fusarium graminearum