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Lazarus Long Profile picture
@LazarusLong13
Nov 19, 2021 • 17 tweets • 7 min read • Read on X
I never want to hear about valveless respirators again.

H/T @PPEtoheros.



Delta said they weren't accepting them.

And THEN the CDC came out against them.

Despite having 624 valved respirators recommended for HCW's on their website. salon.com/2020/08/22/cdc…

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@Delta @AssistDelta - please get your lobbyists to get the @CDCgov @CDCDirector to undo their RIDICULOUS valved respirator stance.

You broke this. You fix it.
Image
Image
3M says, "Nope, valved respirators are not a problem." Image
NIOSH says, "Nope, valved respirators are not a problem." Image
OSHA says, "Nope, valved respirators are not a problem." Image
CDC says "Nope, not a problem," indirectly, by recommending 624 valved respirators in their database for AIRBORNE disease protection. Image
A wet mask is actually a more permeable mask, and less comfortable. Image
Thank you @FredClarkson and Jonathan Hutson for writing this story!
Someone will reply with this study:


@NIST - NIOSH does not use schlieren imaging as part of its testing for a reason.

Please have Staymates stop with this misinformation - and you stop as well.



pubmed.ncbi.nlm.nih.gov/33244212/
nist.gov/people/matthew…
nist.gov/news-events/ne…
Source control for valved respirators is equivalent to surgical masks.

Per the NIOSH.

healthleadersmedia.com/covid-19/niosh…
Boarding planes with elastomeric respirators is intertwined with this valved thread.

Here is the policy, 1st pic👇


The key sentence:
"Masks containing slits, exhalation valves, or punctures"

The order itself, 2nd pic👇
cdc.gov/quarantine/mas…
cdc.gov/quarantine/pdf…

Image
Image
People have been stopped with the elastomeric

EnvoMask.com
A GVS - the valveless GVS and valved look identical.

Which did not sound fun....
What to do to fly safe?

You are not going to get a chance to argue. Grumpy TSA & gate agents? Not worth the no-fly list.

Some strategies.

1️⃣ A valveless elastomeric respirator w/excellent protection that looks like a mask.

I just bought 4, including 1 for Mom - haven't
got it yet, but have done my usual ridiculous amount of research.

- these last for months, so I'd get black.

2️⃣ Already have an elasto? Wear a surgical mask over it.

📌Always bring a fold flat respirator with no valve tucked into your carry-on,prescientx.com/nano-mask
whether you do 1 or 2.

I like these:



Tested very well with masknerd.

And @projectn95 is guaranteed authentic.

Another winner:
@armbrust_usa's


✅ Great breathability.
✅ Individually wrapped - great for traveling.shop.projectn95.org/demetech-dtn95…
armbrustusa.com/products/usa-m…

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More from @LazarusLong13

Lazarus Long Profile picture
May 7
Oh ....

The H5N1 investigation is focused on
/1
fomites and actual droplets.

"....dairy parlor, either through the mechanical transmission, through the milking process, or because there’s continual cleaning going on in the dairy parlor, there are large droplets...."

Despite....
/2 Image
❌ finding PCR positive lung tissueS. Plural, that's right, plural cows.

❌ Asymptomatic cow to cow (no lesions, no milk, so has to be breathed out.

❌ Jumping from wild bird to cattle, cattle to poultry, poultry back to cattle.
Read 5 tweets
Lazarus Long Profile picture
May 6
That Politico story about H5N1 and a power struggle?

I have been tracking this entire debacle, and we only have Hopium left.

A 🧵 of ❌

❌ @JeffreyZients, @WHCOS is personally interested so that this doesn't blow up before November. This means the

politico.com/news/2024/05/0…
CDC will NOT be pushing for access to farmers.

❌ The states ag board and USDA are under control of big dairy and big beef. So, they want it quiet.

❌ The farmers are worried they'll lose market share, and have to spend money on PPE.

❌ The workers are 51% undocumented.
❌ The vets have already tried to change the name to be less scary.

❌ The consumer does not understand any of the above,, or below.

We know:
❌ The mammary gland/udder can act as a receptor milkshake mixer.

❌ That it is airborne.

❌ Workers are not wearing N95s.***
Read 13 tweets
Lazarus Long Profile picture
May 5
1st pic is from the study.

🐄= Cattle Outbreak.
🐓= Poultry Outbreak
🏘️= Neighboring County.
-> = followed by

Idaho Twin Falls County 🐓 2/1.
-> 🏘️Cassia County🐄 on 3/13

Texas Moore County 🐓 3/6
->Hartley County🐄 3/15, 3/17, 3/25, 3/30, 4/3


This is the first study to show the importance of non-waterfowl wild birds in spreading A/H5N1 clade 2.3.4.4b. This is a major shift in our understanding of long-range spread of AIV, as historical long-range spread has been through waterfowl and their specific flyways. The unprecedented spread of A/H5N1 Clade 2.3.4.4b into new species of wild birds increases the risk of other farm outbreaks, as there are 10,727 more non-waterfowl species than waterfowl species in the world. Our analysis supports a single introduction rather than multiple independent introductions. After the introduction, th...
Image
Image
Texas Castro County, 2🐄 on 3/10, 3/13
->🏘️Deaf Smith County 🐓 3/13

New Mexico Curry County, 5***🐄 3/16, 3/28, 3/29, 4/1, 4/2
->🏘️Texas Parmer County 4/1, 🐓
-> 🏘️ Roosevelt County 4/9, 4/10

***Says 4 in the preprint, very grateful for all info!
Image
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Parmer County was listed twice. I think it fits better with the New Mexico grouping - on a temporal basis. Image
Read 8 tweets
Lazarus Long Profile picture
May 3
A cautionary 🧵. The CDC is having difficulty getting access to the farmers to test.

But - what if the CDC got access and discovered a bunch of them tested positive serologically after the fact?

Good news right? A bunch of people got infected, and 50% of them didn't die!
This would mean the CDC's policy of watching ERs for a drastic spike is the right call, right?

Not so fast.

Cross immunity raises its hand.

Basically, previous exposure to influenza A might build up a basic level of immunity.

And this is a hypothesis laid out here.... Image
This is from some scientists in 2015.

But- this is 2024. Why would dairy workers in America have exposure?

ncbi.nlm.nih.gov/pmc/articles/P…
If cross-immunity is sufficient to resolve mild infection, specific H5N1 antibodies might not be produced and thus not detected. Consequently, in regions with frequent environmental exposure, the population would be less likely to generate specific H5N1 antibodies. Seroprevalence surveys in these regions may thus yield low positive results for specific avian strains, in particular less common strains such as H5N1 (e.g., 0 in Thailand and Indonesia). Further, due to partial protection conferred by cross-immunity, a higher dose of H5N1 would be needed to overwhelm the immune system to cause s...
Read 9 tweets
Lazarus Long Profile picture
May 2
You will want to read this 🔥 study 🔥 on bird flu in cattle yourself.

I am going pull out the highlights that I am interested in - 🧵

First...what he said
Image
There are most likely infected herd we don't know about. Hopefully, this gets nipped in the bud.

(I wrote "hopefully". Foreshadow: hope was crushed.)

HPAI lasts about 2-3 weeks.

Asymptomatic is happening - but we could still stop it- with asymptomatic testing. (My notes) Image
It went from Texas to Kansas, Michigan, New Mexico, North Carolina, Idaho.

Kansas to South Dakota.

Areas that get more infected cattle will have more opportunities to get to know that reassortment means interspecies transmission and pandemic potential.

ncbi.nlm.nih.gov/pmc/articles/P…


Epidemiological records documented dairy cattle movement from a Texas herd (at shipment, HPAI status was unknown) to North Carolina and Idaho (Fig. 1). Records also indicated that asymptomatic dairy cattle, some that were subsequently diagnosed as HPAIV positive, were moved from a Texas herd to Michigan and to Ohio, and a Kansas herd to South Dakota. We also applied an asymmetric discrete-trait model with Bayesian stochastic search variable selection to reconstruct how clade 2.3.4.4b HPAIV H5 isolated in cattle moved among the eight US states (Idaho, Texas, Kansas, Michigan, New Mexico, Nor...
Areas that received large shipments of cattle and their viruses will provide more opportunities for reassortment and the potential emergence of IAV strains with phenotypes that may have increased zoonotic potential.
reassortment is most prominently described for influenza viruses as a primary mechanism for interspecies transmission and the emergence of pandemic virus strains [3–5]. For instance, reassortment accelerates the rate of acquisition of genetic markers that overcome adaptive host barriers faster than the slower process of incremental increase due to mutation alone. The emergence of new influenza genes in humans and their subsequent establishment to cause pandemics have been consistently linked with reassortment of novel and previously circulating viruses
Read 7 tweets
Lazarus Long Profile picture
May 1
"Scientists tried to give people COVID — and failed.".

This is how the article wants you to retweet when you click on the X/Twitter button.

But this is NOT the real take-away.

The real take-away?
/1
nature.com/articles/d4158…
Scientists tried to give people COVID BY DROPLET— and failed.".

From the study itself, here is the procedure.

Literally dropping droplets into the nose.

And this is the ball game, folks.
The purpose of this study was also in part to find out if droplets cause Covid.

Image
Image
Image
But the scientists involved were focused on the dosage involved, and ignored the fact that it was droplets failing.

A few folks might find this amusing to see the real take-away ignored from the human challenge study:@kprather88 @jljcolorado @trishgreenhalgh
Read 8 tweets

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