NOTE:

Do NOT use rapid tests in the cold.

If using rapid tests this holiday season and asking ppl to test before a gathering… or any time…

Suggest they be done before leaving the house, or in the car, etc. Someplace >55 F
Also, if your counter or table or wherever you are letting them sit for the 15 minutes is cold (like a granite countertop) - place it on top of the box or literally any other surface that’s not cold (wood table, book, etc)
Also - this is not the same as storage. If they are sitting inside the box not being used yet, then store ideally in a slightly cooler location - but don’t let them freeze - it can potentially impact their chemistry.

Ideally store below 80F
Using the test in the cold can cause false negatives Bc the reagents may not bind virus well or show a line.

It’s ok if your nose is cold and the test is warm. But maybe let your nose warm up a bit too before swabbing.
Here is a good general descriptor for storage.
As others have graciously pointed out - the counter is not actually colder - it’s room temp.

Important Point is to not use on a cold surface and r in a cold environment.

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More from @michaelmina_lab

4 Dec
I absolutely hate this title in ⁦@TheAtlantic

To say we know nothing completely neglects the research, learnings and experience of past 2 yrs.

We know SO much about Omicron.

Relative to ALL we DO KNOW, the things we don’t know are minor

1/
theatlantic.com/science/archiv…
This reminds me of early 2020 when we forgot so much of what we knew of epidemiology, immunology, infectious disease & thought we needed to rewrite textbooks. But we knew so much about this before it was ever detected

It is a textbook resp virus

2/

coronavirus.medium.com/sars-cov-2-is-…
The reporting is really nice. But the title attached to it is frustrating to say the least.

It screams loudly and demonstrated well how we have thought about the importance of the unknowns compared to the knowns of this virus this entire pandemic.

3/
Read 10 tweets
1 Dec
🧵

This issue Re: Trump and positive UNdisclosed test just got crazier, and I need to update / fix my thread below

First, I was incorrect on timeline

Trump likely did NOT use a Test before Rose Garden Event

Fitting early reports that he was not compliant

1/
Trump tested AFTER the Rose Garden event

He was notified of positive molecular test AFTER he was already on his helicopter out of DC

He was then notified by WH of a “negative” repeat test performed on BinaxNOW while he was STILL on helicopter

This begs the question…

2:
How did WH perform BinaxNOW test to confirm initial positive if he was already on helicopter and didnt return for follow up test??

Most likely scenario is they used an adulterated swab that was already in a molecular reaction and then placed that same swab into the BinaxNOW

3/
Read 5 tweets
1 Dec
Anti-viral treatments are here

BUT, the life saving treatments must be started FAST <3 days of symptoms

Most ppl take 2+ days deciding to get tested then days to result

I joined eMed @eMedCertified to help solve this problem!

*Test to Treat* at home
1/
nytimes.com/2021/11/29/hea…
The therapies work best when started early

Immediate access to tests is a problem in much of the US, esp high risk individuals

Between determining you have symptoms, making an appointment, getting tested, waiting for results… starting in <3 days from symptoms is unlikely

2/
Medicare/others should place rapid tests in high-risk people homes with rec to use the test moment symptoms are felt. Use with a telehealth proctor.

If test is positive and person fits criteria, an Rx can be ordered and medicine delivered to them at home

Test to Treat

3/
Read 4 tweets
1 Dec
Was Trump the superspreader?

For a year, I’ve suggested Trump was the likely superspreader at White House Rose Garden on 9/28/20

All were supposedly tested, so how would a superspreader enter?

Now we know Trump tested COVID positive 2 days earlier.

1/

theguardian.com/us-news/2021/d…
He was testing daily and on Sept 26th, 2 days before the Rose Garden Superspreader event, he tested positive on a fast molecular test.

Bc he was testing so frequently, he was likelu detected using a molecular test at the earliest time, before becoming infectious.

2/
So when he immediately tested again with a rapid Ag test, it did not yet register positive because he was not YET infectious

Had he used a rapid test later that day or next day though, once he was becoming slightly infectious, he almost certainly would have been positive

3/
Read 13 tweets
30 Nov
Many countries are asking for proof of vax, or testing to travel

I don’t understand this. Vax work Well to stop disease…

But it’s time to clarify they do not stop transmission. They slow it down

But it simply is not appropriate to assume that vax = not infectious

1/
If we don’t appreciate this soon immediately, then we will see irresponsible policy that allows the virus to keep on spreading.

This is almost certainly even more true for Omicron which, if anything, will spread more efficiently, not less, than other variants among vax’d

2/
We can be fully transparent about what vaccines do very well (protect you!) and what they are not doing very well (stopping transmission) while still advocating for everyone to be vaccinated

Most ppl see this and any lack of transparency harms vaccine uptake even more.

3/
Read 11 tweets
30 Nov
🧵

This from ⁦@CDCgov⁩ is exactly why Rapid tests are important!

A PCR 2 days before an event, flight or (fill in blank) does NOT reflect you today

2 days ago can be neg but you can be a superspreader now

A rapid test used just before the event is always best.

1/
Its remarkable & contradictory that while CDC makes this figure 👆showing that neg tests 3 days before do not mean you’re negative on thanksgiving… while still recommending testing 2-3 days before travel.

The safest approach is to recommend a rapid test hours before travel

2/
In the midst of Omicron, instead of border lockdowns, we can use rapid tests just before a flight. Could even consider a PCR 24-48 hrs before amd a rapid test just a couple hours prior to flight.

3/
Read 4 tweets

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