THREAD on UK covid situation, Omicron and what's happening...

TLDR: Omicron increasing very fast and we are getting increasing evidence of significant ability to infect previously infected or vaxxed people.

Expect UK response to change rapidly in response. 1/10
First, UK cases are climbing, back to near January pandemic peak levels. Scotland and England are rising fastest in recent days.

In England, London is rising faster than other regions.

Cases highest in 5-14 yr olds but rising fast in 20 somethings recently... 2/10
As of end last week, people in hospital going down everywhere except England, where admissions are now going up, driven by 18-64 year olds.

Unfortunately, if cases go up sharply in next few weeks, admissions will follow. By how much is the question... 3/10
The govt, SAGE, UKHSA are all warning of a big new wave in cases driven by rise of Omicron over the coming weeks.

What we don't know is how bad the consequences will be - but it is certain that they will be worse than they would have been without Omicron. 4/10
Latest UKHSA report confirms that Omicron is doubling every 2-3 days in UK & does have a large growth advantage vs delta.

Also that vax efficacy takes a big hit - you *really need* the booster dose to protect against Omicron infection.

Full thread:
5/10
Since data for tech report, Omicron was almost 10% of cases in England by last Wednesday (now likely much higher). Also likely dominant in London by now -> already 30% cases by Weds.

Highest Omicron in 20 somethings in London. 6/10
So about 35% of UK has that third dose right now. We're giving about 400k+ doses a day which is good but we need to speed up given speed of Omicron.

Plus millions of children don't even have 1 dose let alone 3. 5-11 a priority for vax if we want to protect them next term. 7/10
The NHS is under a lot of strain already - *without* Omicron added pressure. See this thread:


Unfortunately many over 50 have waned 2nd doses & NO booster. Vax is *lowest* in London where Omicron is highest (68% 1 dose in over 12s vs 89% in England) 8/10
With the some Omicron cases now being admitted to hospital, we know that even vaccines blunt a lot of the severity of illness the sheer size of the Omicron wave could be overwhelming. Hence also the rising threat level. 9/10
Cases likely to escalate quickly in coming weeks, with potentially severe NHS consequence in Jan.

Expect response to change v rapidly too.

Best case is any vax dose stays great vs severe illness. We don't know about Long Covid.

We do need to protect kids & vulnerable. 10/10
PS quite possible that we can't test all the people wanting tests so *confirmed* cases might well not rise as fast - but because of testing capacity and not because cases aren't there to be found.

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More from @chrischirp

Oct 19
Important 🧵on our new peer-reviewed paper:

The pandemic is as bad as it ever was for babies - in year to Aug 2023, 6,300 babies under 1 were admitted to hospital wholly or partly BECAUSE of Covid.

They are ONLY age group where admissions have NOT gone down over time 1/17 Image
Our study, led by Prof @katebrown220, looked at all hospitalisations in England in children with a Covid diagnosis or positive test from Aug 2020-Aug 2023.
We then *excluded* all admissions where a Covid diagnosis was incidental (ie not why they were in hospital)
2/17 Image
Infants (babies under 1) are generally at higher risk from respiratory infections, plus they are the age group that, if infected, are overwhelmingly meeting the virus for the first time.

They are not vaccinated and have not had it before. 3/17
Read 18 tweets
Sep 26
Prof @Kevin_Fong giving the most devastating and moving testimony to the Covid Inquiry of visiting hospital intensive care units at the height of the second wave in late Dec 2020.

The unimaginable scale of death, the trauma, the loss of hope.
Please watch this 2min clip.
And here he breaks down while explaining the absolute trauma experienced by smaller hospitals in particular - the "healthier" ICU patients were transferred out, leaving them coping with so much death.

They felt so alone.
Here Prof Fong explains how every nurse he met was traumatised by watching patients die, being only able to hold up ipads to their relatives and how it went against their normal practice of trying to ensure a dignified death, with family there.
Read 5 tweets
Aug 28
THREAD: I asked what the point of Public Inquiries is for @bmj_latest

We've spent hundreds of millions of £ on Inquiries over last decades, generating deep understanding of failures & 1000s of recommendations.

But v few recommendations get implemented!
What is going on?

1/12 Image
E.g. Covid-19 Inquiry has cost £94 million so far - and is projected to cost over £200m by its end (it still has years to go).

1st report published (out of at least 9) found major flaws and proposed 10 recommendations.

Chances are low that they will be implemented :-( 2/12


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Inst for Government looked at 68 Inquiries from 1990-2017.
The Inquiries cost over £630 million and made 2,625 recommendations.

Only 6/68 Inquiries have received full scrutiny by a parliamentary select committee on implementation of recommendations. 3/12 Image
Read 12 tweets
Aug 9
🧵War causes direct civilian deaths but also indirect deaths over the following years.

Recent paper estimates eventual total direct & indirect deaths in Gaza attributable to the war - 10% of entire pop'n.

I want to explain these estimates and why deaths must be counted. 1/13 Image
Why count casualties from war anyway? For moral, legal and strategic reasons.

1 - owe it to those who have died
2 - International law says must count & identify dead as far as possible
3 - monitor progress of war & learn from tactics

2/13 Image
There are direct and indirect casualties of war. Direct deaths include those who killed by fighting or bombs.

Indirect deaths are those that die when they would otherwise have lived because of one or more of: lack of food, healthcare, housing, sanitation, income, hope. 3/13 Image
Read 14 tweets
Aug 1
THREAD: the summer Covid wave in the UK continues.
Basically, there is a LOT of Covid around and not a lot of other respiratory viruses.

If you have cold or flu symptoms, it's probably Covid.

The latest hospital data from England shows steady, quite high levels. 1/8 Image
But admissions don't tell us how much virus is circulating more generally. The best (but imperfect) measure we have is wasterwater measurements, and only in Scotland and not England.

Scotland's wastewater is showing a huge July peak - highest since Omicron's 1st yr in 2022 2/8 Image
Because different people shed different amounts of virus and variants can matter too, you can't for sure infer how many people were infected between different wasterwater peaks. BUT given the size, I'd say it's pretty likely this is the largest peak since 2022 in Scotland 3/8
Read 8 tweets
Jul 23
THREAD:
I wrote about Baroness Hallett's Inquiry Module 1 report for @bmj_latest .

She found that there was *never* a plan to keep a pandemic death toll down - I discuss this and what it means going foward.

Main points below: 1/14 Image
The headline most seen is that the UK planned for the wrong pandemic.

While it is true that was far too narrow a focus on a flu pandemic, that is not the most telling bit.

To me the most telling bit, is what the plan did NOT do 2/14


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The issue is less the wrong disease, but that there was never a plan to prevent one at all – of any disease type.

The plan was *never* about reducing the number of pandemic deaths. 3/14 Image
Read 14 tweets

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