It's quite extraordinary that the government has not immediately mandated everyone use high quality masks in all indoor spaces (when mixing with people from outside your household).

Imminently the number of cases of Omicron are going to be extraordinarily high. 1/n
Note: many of these will have two vaccinations, many will be boosted too. Hopefully in those with boosters this will provide a significant amount of protection against severe disease, death, and long COVID. 2/n
However! The more transmission we have, ⬆️ mutations in the virus. In a highly vaccinated population, this gives the virus the opportunity to mutate to further evade our antibodies against it, & to become more transmissible, more infective, more pathogenic, more virulent. 3/n
However bad you think it is now, it can and will get worse if we do not suppress transmission. The trend on this has been very clear.

If we reduce our social interactions, and wear effective FFP3/FFP2/N99/N95 masks when we do, we can enormously reduce the number of ... 4/n
... opportunities the virus has to replicate, which will reduce the speed of emergence of yet more mutations, and more immune evasive variants of concern.

Effective masks should be the first line of defence that we ALL use.

No excuses. No exceptions.

5/end
P.S. The Government are not ensuring that all doctors and nurses are provided with effective PPE, nearly two years into the pandemic, despite the Government deliberately choosing to put in place policies that would increase transmission since May. They are utterly negligent.
By no means the first time I have been calling for all in the NHS to be provided with effective PPE

We know FFP3 masks can reduce transmission of SARS-COV-2 to zero

@BorisJohnson and @sajidjavid
you must provide then to all HCW now. Do not delay.

Immediately go on a war footing to produce enough for the country. #BetterLateThanNever.

Huge concern how many healthcare workers will be three months past their booster jab by the time Omicron peaks.

We cannot sacrifice these precious people who risk their lives for us.

We MUST all call for healthcare workers to be provided with FFP3 masks

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More from @0bj3ctivity

16 Dec
Oh my word!🤦‍♂️

If you haven't already, you most watch yesterday's 5pm government press conference, and read the gaslighting BBC article from Nick Triggle below (end of thread)

The government approach now is like in March 2020. Herd immunity by infection (which we ...

1/n
...already know is dangerous and doesn't provide durable immunity), difference this time however is that he isn't advocating to flatten the curve and protect the NHS

@Peston and @bbclaurak asked the PM yesterday with exasperation about how the immunity from the booster will
2/n
...come too late, and why wasn't the Government taking tough action immediately. The answer was telling. The points were accepted, but vaccination is still the only game in town. We should be shutting indoor hospitality immediately, and mandating the use of effective masks, ..3/n
Read 10 tweets
15 Dec
Article suggesting that "coronavirus infects both fat cells & certain immune cells within body fat, prompting a damaging defensive response in the body"

“Whatever happens in fat doesn’t stay in fat ... it affects the neighboring tissues as well"

nyti.ms/3oDdcO2
My immediate thoughts

1) Is this going to get through peer review?

2) can SARS-COV-2 hide beyond the reach of immune system in fat cells?

3) does the virus get released again if someone loses weight?

4) what are the implications for persistent disease / relapse / long COVID?
"Environmental pollutants and other toxins are stored in fatty tissue. During weight loss, fat breaks down and toxins are discharged into the bloodstream"11 Jan 2017

So why not viruses too?

sciencedaily.com/releases/2017/…
Read 7 tweets

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