Prof. Christina Pagel Profile picture
Dec 17, 2021 18 tweets 9 min read Read on X
THREAD: on omicron, UK cases, London & what to do next...

Last post-briefing tweet thread of the year! 1/18
First Omicron... as of 11 December, Omicron was most common in Scotland and England but starting its growth in Wales & N Ireland. With its growth speed, shares of cases will now be much higher in all regions. 2/18
In England, UKHSA "S gene dropout" data shows it was 40% of cases by 13 DEcember. It will be dominant in England by now.

WHO first designated it a variant of concern & named it Omicron 3 weeks ago today. Crazy. 3/18
In England, it's growing fast in all regions (less than 2 day doubling time in many!) but is highest in London which is maybe 5 days ahead of other regions. 4/18
Imperial college released a report today showing high immune escape, rapid growth and no evidence that omicron was milder than delta.

imperial.ac.uk/media/imperial… 5/18
Nationally, cases have reached record highs. Another record reported today.

Growth might slow over next few days because:
- school holidays
- delta might decline cos of boosters
- weekend
- testing backlogs 6/18
In fact on testing, we can see that we are doing tons of LFDs and the most PCR tests ever. Testing times are getting longer.

We might reach testing capacity next week, artifically flattening reported cases. 7/18
Back to cases... unsurprisingly (given where Omicron is most prevalent), Scotland and England are rising rapidly while Wales and NI still flat... Expect that to change over the next week.

Note that cases in under 11's sky high. Schools will be big issue next term. Again. 8/18
People in hospital are falling or flat everywhere except England where admissions are also going up. These are still mostly Delta!! Omicron admissions will start to be felt from next week on I think. And will (at least at first) be on top of these Delta ones :-(

9/18
Meanwhile we are seeing more Covid outbreaks in hospitals. We need to watch this because Omicron seems ridiculously catchable. Hospital workers need to be provided with upgraded masks asap.

bbc.co.uk/news/uk-wales-…
10/18
Deaths are flat - do not expect recent case rises to be reflected in deaths for several weeks yet.

We are accelerating booster jabs - almost 800K in one day recently. We need to keep at that level and go even higher to reach people as soon as possible. 11/18
Soooo, let's talk about London where Omicron is now the large majority of cases.

It's the fastest growing region by far in terms of cases, positivity rates and hospital admissions. Many boroughs are showing insane recent growth. 12/18
Hosp admissions by primary diagnosis show increase in *both* admissions for Covid and more incidental admissions (e.g. trauma or caught covid while in hospital for something else).

This is consistent with no evidence that Omicron milder.

Critical care already v busy. 13/18
Cases are going up fastest in 20-29 year olds but all age groups in London are going up - even school age kids where cases *had* been dropping towards the end of term. 14/18
London is the least vaccinated, least boosted region of England with large difference by deprivation, espeically in the over 50s. This means vulnerable populations will be massively exposed to, and at risk from, Omicron. What are we doing to address this? 15/18
So overall things are not looking great.

Indie SAGE suggests having a mini circuit break until Christmas eve to stop as many people as possible getting infected next week - this will save lives, protect NHS and allow limited mixing over Xmas.
16/18
And this *must* come with govt support for affected businesses - they are already suffering greatly from voluntary cancellations (and I think need support regardless).

17/18
And finally, we *must* vaccinate the world. @UNHumanright reported over 100 companies able to produce vax that are not allowed to.

It's not a zero sum game. UK must support vax waivers and tech transfer to enable much higher vax production globally. 18/18

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Prof. Christina Pagel

Prof. Christina Pagel Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @chrischirp

Jun 4
As ever, I am getting lots of pushback.
Here is a compilation of the European countries I've found with recent wastewater data. Some are going up a bit, some down a bit, some are flat, none are anywhere near previous peaks.
I can't see anything here to be panic anyone. 1/3
Image
I can't find the dashboard for Spain, but others saying it is in a wave. Perhaps it is. England has just had one - the last data we had (a couple of weeks ago from Bob Hawkins) looked as if our wave had peaked.
So, I'm not seeing reason to think things are terrible here! 2/3 Image
Yes there are new variants growing right now. They are not growing faster than JN.1 grew in December and that wave did not end up as bad as feared.
Clearly it remains true that Covid is NOT a seasonal disease (unlike Flu and RSV)
3/3
Read 5 tweets
May 8
Quick thread on the Astra Zeneca (AZ) covid vaccine since it's been in the news today.

TLDR there isn't a new "smoking gun", the AZ vax was one of first and cheapest, it saved millions of lives globally, there are better vax out there now, adapted to new variants 1/9
the AZ vaccine was one of the first approved at the end of 2020, cheaper than Pfizer, and - importantly - easier to administer in lower resource settings as it didn't require super low temperatures for storage 2/9
In most countries it was first rolled out in older adults. As it was rolled out in younger adults, a *very rare*, serious, side effect was noticed - it could cause deadly blood clots

This was spotted quickly and studied. Vax monitoring did its job. 3/9 Image
Read 11 tweets
Apr 2
A short thread on why this is not a scary chart and why all the evidence suggests that there is not much Covid around right now. 1/6 Image
the above chart is recorded covid hospital admissions / reported covid cases. It is close to 100% now *because basically only hospitals can report cases since Feb 2024*

It is to do with changes in case reporting and NOT hospital testing
2/6
In fact hospital testing has been steady since the change in testing a year ago (only symptomatic patients get tested now).

The % of people PCR tested who have Covid is 4% - there is no evidence that there are loads of symptomatic people in hospital being missed. 3/6
Image
Image
Read 6 tweets
Dec 21, 2023
Beyond a shadow of a doubt that England is in its biggest Covid wave for well over a year now, with latest ONS infection survey results published.

I've written about it here
1/7 tinyurl.com/ru7h3m28
Image
The UKHSA have now published their modelled estimates of what percentage of English population has Covid. And as of a week ago it's high (4.3%) and rising.

Read all about it here!
2/7
It's highest in London, South East and East & in young and middle aged adults.
The main thing is it's going up and fast, so prevalence will already by significantly higher now than it was last week. 3/7
Image
Image
Read 8 tweets
Nov 30, 2023
Short thread on what I said on Channel 4 news tonight.

1. Did I find Hancock a sympathetic witness?

A: I find it hard to have sympathy for someone who repeatedly claimed to have thrown protective ring around care homes, while discharging covid+ patients into them.

1/5
There were *28,000* excess deaths in care homes Apr-May 2020.

Harries thought it was "clinically reasonable" not to treat covid +ve residents in hospital. Even it was, it was NOT reasonable to return them somewhere they could infect so many other very vulnerable people. 2/5
Image
Image
2. Did I think scientists bear blame for not emphasising asymptomatic transmission?

A: No, because they very clearly did advise there could be asymptomic transmission before March 2020 - sources in next tweet. 3/5
Read 5 tweets
Nov 30, 2023
Hancock: "there was no way we could allow the NHS to become overwhelmed"

Except, the NHS WAS overwhelmed

Here is what NHS staff said about that time - Pls read whole 🧵
"Heartbreaking"
"Horrific"
"It broke my soul"
"We cried, we came home exhausted. We were overwhelmed"

1/16
"Overnight we were told that all “safe working rules” were gone. There was no choice, we were forced to do it"

"It felt like a death sentence. It felt out of control"

"We were put on wards with no senior support, sometimes makeshift ... with little of the right equipment"

2/16
"Terrifying. A huge sense of duty ... but also terror. We were unprepared & ovt clearly had no plan"

"We had patients on wards on 19 litres of oxygen - this would never happen under normal circumstances - they’d have come to Intensive Care but we didn’t have the space"

3/16
Read 17 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(