"Decollage!" You ever hear a common word and you start wondering about it's origins?
The word "Decollage" is from french verb "decoller" - opposite of french verb "coller" - which means to glue or stick.
English translation is "take off" but maybe "unstick-ify" better.
(and when you were a kid, you made a "collage". Sticking stuff together on construction paper with glue sticks, right?)
So...here's where I ponder. I worked in France for 3 years doing solid-bound organic synthesis. We used the french words "accrochage" and "decrochage" to mean "attach" and "unattach" the molecules from their solid support. But the French verb "accrocher" means "to hook".
"Accrocher" : "hook or hang" is a physical process, right? "Coller" : "to glue or stick" is a chemical process. So maybe we chemists were using the wrong word, if you dig down to the molecular level...

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More from @mike_malaska

27 Dec
Going to thread up some pix from today's #geology hike at #VasquezRocks.
(Why are those rocks right there? We'll get to that...) 🧵 In midground, tilted sandst...
Here is a descent into a canyon in S end of park. That's where the geology story gets really wild. Image
Here's a view of a tree from a ridge where I measured strike and dip of the layers using a compass. Yellow green fall foliage t...
Read 28 tweets
31 Oct
This is hilarious!
"Because everyone knows that carbon can only have four bonds, right?"

(Well, that's kinda not true....)
[thread]
...and yes, I do find this photo hilarously nerdly. And am just gonna riff off it here.

It was drilled into my head in organic chemistry that "carbon can only have four bonds" and "Haha, you drew a pentavalent carbon! That is WRONG! Points off!"

But...it can have five bonds!
And how that works is very interesting, and maybe one of the most important things in the Universe for organic chemistry.

Carbon can have 4 sp3 hybridized orbitals around it in tetrahedral geometry. But, if you stick a proton on it, it can rearrange.
Read 20 tweets
5 Jun
“Astronomy and Astrology are pretty much the same thing.”
And with that, I’ve pretty much pissed off every amateur and professional astronomer. But, there are really strong and provable connections.
Strap in for a long thread, and a wild ride. [1/n]
(with side links to explore)
Astronomy makes observation of the heavens, and predicts/explains physical properties and timing of those objects.
Astrology makes observations of the heavens, and predicts/explains spiritual or human-centered properties and timing.
(Starting data same, applications different.)
Looking at history, astronomy and astrology pretty much the same until 1700's, when the Science and beliefs kinda split out. Astrology goes way back. Prolly every culture had their own “sky-watcher” to look at heavens and figure out what to do.
(en.wikipedia.org/wiki/Archaeoas…)
Read 33 tweets
4 Jun
Well, this is great news!
FDA approval for vaginal yeast infections!
fiercepharma.com/pharma/scynexi…
This comes from the company that I (and many others) helped found, back in 2000-ish. I was not directly involved in this, but my colleagues (led by a former post-doc of mine) made this happen.
I sat in on some of the meetings, and worked for the same client (Merck) on parallel projects.
This started as a modified derivative of a natural product molecule called enfumafungin.
Read 8 tweets
16 Nov 20
I learned something today in #astrobiology that just totally blew my mind.
There are microbes that eat....air. And can live on just....air.

[thread]
These microbes live in cold deserts...I mean really brutal cold deserts. Barren rocky ridges (not even tundra) in Antarctica.
There's really no free water - very dry. And dark for 6 months, too. So these microbes live where there isn't enough water for photosynthesis producers.
They live on the trace amounts hydrogen gas (H2) in the atmosphere (about 190 parts per BILLION), and CO (20 parts per BILLION). So these things are living on tiny tiny tiny amounts of stuff.
But...they are still living.
Read 16 tweets
6 Jun 20
@mikamckinnon @SiO2moyer @justinboldaji Carlsbad and Lechuguilla Caves have a really wierd and fascinating geology history. They were made by bacteria!
@mikamckinnon @SiO2moyer @justinboldaji The story goes like this. Gypsum laid down. Then...thick thick limestone laid down on top of that. Way way down deep, microbes eat gypsum, H2S bubbles up. (Microbes reduce sulfate). ((there might be other ways H2S bubbles up.)) That gets H2S percolating up into the limestone.
@mikamckinnon @SiO2moyer @justinboldaji Then, up higher in the limestone layers, there are places where oxygen in water mixes with H2S charged waters. Some bacteria love this! They can eat H2S in the water and combine with O2 in the water and get energy!!!
They pee out sulfuric acid! (H2SO4)
Read 15 tweets

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