as we come to the end of the year, let's do a quick recap of the year in review for #NephJC

We discussed 24 topics in 2021, including
14 RCTs
6 observational studies
3 guidelines
1 book club
nephjc.com/news/?category…
New this year was the #NephTrials initiative with @ISNkidneycare with 3 chats on
- Cluster RCTs
- Pragmatic RCTs
- Run in periods
More to come in 2022
nephjc.com/news/tag/nepht…
nephjc.com had ~ 450K + page views in 2021
some oldies (eg nephjc.com/news/rasaftera… from @roxytonin)
or the COVID pages nephjc.com/covid19 have high traffic, but let's review the 2021 #NephJC summaries which received the most page views (so far)
at #10 was the summary of the new GFR equations from @NEJM nephjc.com/news/new-gfr-e…
Summary by @Slatts_1 @kidney_boy & @hswapnil
#VisualAbstract from @MdYoshinosuke
at #9 was the BASICS trial in @JAMA from @f_g_zampieri et al
nephjc.com/news/basics summary for #NephJC by @hellokidneyMD who also made this great VA and this superb comparative table
at #8 was LANDMARK, which set out to show Lanthanum is superior and demonstrated the exact opposite

#NephJC Summary by @SRameshMD and @jadav_md nephjc.com/news/2021/7/20… with a commentary nephjc.com/news/landmark-… by @hswapnil
and VA by @dr_missyhanna
This time with the #VisualAbstract from @dr_missyhanna 😅
#7 was the Roxadustat trials from @KIReports
#NephJC summary from @Deep_Phachu & @priyamisdead
nephjc.com/news/2021/2/23…
VAs from @alunieczka & @drkeia

+ a wrinkle, as we have updated on the blog
We discussed the stats shenanigans with @DrDanMO here nephjc.com/freelyfiltered…
coming in at #6 was the ADVOCATE trial on Avocapan for ANCA vasculitis - another advance in this area

(watch out for the steroid dose of course)

#NephJC summary by @Elena_Cervants @drkeia and @alunieczka

#VisualAbstract from @Deep_Phachu
Coming up are the top 5 by page views (which skew to older discussions of course)
and at #5 was the discussion of the AURORA trial
Voclosporin sparkles for Lupus
#NephJC summary by @bourneauguste and @JMTeakell nephjc.com/news/2021/6/21…
An inspired VA by @katierizzolo

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More from @NephJC

3 Jun 19
Welcome to the @NSMCInternship #tweetorial for this week’s study on a new risk prediction tool for IgA nephropathy, appearing in @JAMAInternalMed. Check out these unhappy glomeruli with mesangial IgA deposits in green from pathologyoutlines.com (1/16)
Recent unsuccessful #RCT: STOP-IgA (immunosuppression+supportive care isn’t superior to supportive care alone) & TESTING (corticosteroids reduce risk of #ESRD but cause serious infections) were covered by @NephJC: nephjc.com/iga-nephropath…
and nephjc.com/news/2017/8/28… … (2/16)
Question for the #NephTwitter: What percentage of patients with IgA nephropathy develop #ESKD by 10 years? (3/16)
Read 16 tweets
15 May 19
1/ #Tweetorial #NephJC #Hypernatremia Reviews and guidelines say to correct hypernatremia in adults by no more than 10 mmol/L per day. This is based on little hard data, has little support in literature and may be harmful nejm.org/doi/full/10.10…
2/ What rate do you target for the correction of chronic (>48 hours or present on admission) hypernatremia #NephJC
3/ The rapid lowering of serum sodium will lower the tonicity of the extracellular compartment. Water will then be osmotically drawn into relatively hypertonic intracellular compartment. This can cause cerebral edema and increased intracranial pressure. #NephJC
Read 19 tweets

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