THREAD on UK Covid situation:

TLDR: not over yet. Good news is high booster coverage in over 50s & no rise in ICU. Bad news is high strain on hospitals, no plan for schools & worsening admissions & long covid for kids.

+ Indie Sage has some suggestions...

1/21
Firstly Omicron - now dominant in Scotland, Wales & England. Probably in NI but no recent data. N Ireland is about week behind other nations.

Omicron dominant in all English regions, London c. 1 week ahead.

Omicron's rise has been very rapid! 2/21
Omicron is v good at infecting vaxxed people - even being boosted only gives you about 40% protection after 10 weeks.

Booster gives *88%* protection against hospital admission - GET IT!

NB booster hosp protection for Delta was close to 100%, Omicron has made things worse. 3/21
So given boosters so important... over 50% of whole population boosted everywhere except N Ireland.

Massive booster effort before Xmas but doses have dropped now :-(

England & NI behind on teen vax (about 50% have received 1 dose). 4/21
By age (England), we have excellent booster coverage in over 60s - this is making big difference to admissions and is why e.g. N America in harder situation. BUT plenty of unboosted younger adults left and kids have v little vax protection. 5/21
Plus very large gaps in booster coverage for adults and first dose for teens by deprivation.

We *have* to address this because it will only exacerbate existing inequalities if ignored. 6/21
In terms of cases... 3 million cases in last 3 weeks - same as in the whole 12 weeks before that.

Cases & positivity rates at record highs in all nations. Testing is struggling - ONS infection survey (not affected by test capacity) shows this peak dwarfs previous ones. 7/21
Reinfections are also rising - over 140,000 in England in last two weeks - these are *not* on the daily dashboard (but will be soon). Wales & NI do include these and so will be reporting relatively higher case numbers. 8/21
Regionally, London has dropped since pre Xmas but recent days flat. all other regions rising still.

Positivity rates rising everywhere (inc London!). ONS also shows recent fall in London but age profile is interesting... 9/21
Overall in England, confirmed cases in all ages are rising. ONS shows we're likely undercounting primary school kids - extremely high rates!

Kids are returning to school & young adults to uni with highest ever prevalence. 10/21
In London, drops in school age children and young adults since just before Xmas - but flat in most recent days - *before* any new year mixing impact.

Cases in older adults are still rising (although might be flatting in over 70s). What does this mean for hospitals? 11/21
Number of people in hospital with Covid is going up sharply - not *that* far from wave 1 peak.

BUT few people are needing intensive care - pressure there is NOT rising.

Both admissions *for* & *with* covid are rising steeply, *but* percentage for is falling. 12/21
There is a lot of staff sickness - climbing steeply.

This, combined with covid pressure + high existing hospital load + social care pressure, means many hospitals are in crisis.

NHS doesn't have same resilience 2 yrs into pandemic. NW particularly stressed. 13/21
Deaths are hard to interpret right now with reporting delays over holiday period, but are likely flat or slightly increasing.

With fewer people needing intensive care and high boosters in older adults, hope that deaths will not increase too much... 14/21
If we look at the age of admissions, they might be peaking in 18-64 year olds but still going up in over 65s.

Admissions are at record highs for under 18s, *particularly* for *0-5s*.

More children have been admitted with Covid in *last 3 weeks* than *whole of 1st wave*. 15/21
If we look at long covid, children reporting symptoms longer than 4 weeks has shot up, sharply reflecting high case numbers in Sept & Oct. Adults in their parents' generation (35-49 yrs) also reporting increasing long covid. 16/21
Long covid reports in 17-24 yr old has fallen, reflecting more people recovering than being added as cases have fallen - good. But we've just seen record cases in this age group - and we have no idea about Omicron and Long Covid. Vax should help, but no omicron data. 17/21
As for kids - we know they've got more months of high (Delta) cases that will increase long covid. AND they've returned to school & likely Omicron wave. What then?

With increasing long covid & hosp admissions & little vax, we must stop pretending covid fine for kids. 18/21
Also, a new school wave will prolong the Omicron wave for everyone, and further risk school staff (already reporting more long covid alongside health care workers).

AND high school cases disrupt education for kids who fall ill and those left without teachers. 19/21
So @IndependentSage think it's too late for a circuit breaker - time for that was in Dec. Now it's about reducing the "comedown wave" as fast as possible through:
communication (symptoms, airborne)
protection (clean air, masks, vax)
support (isolation, clean air, industry) 20/21
Different ages will peak at different times. The risk of "muddling through" is that we face a slow descent, resulting in far too much illness, disruption and prolonged NHS pressure.

We didn't slow growth of Omicron, so let's now accelerate its decline. 21/21
PS incidentally, all the measures we've suggested are important for new variants, and most for new airborne diseases...

PS2 thanks to Bob Hawkins for his help as ever.
PS3 you see same patterns of long covid (but lower numbers) when looking at symptoms for longer than 12 weeks - but that still only includes people infected up to September because of lags and so misses school wave.

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More from @chrischirp

Oct 19
Important 🧵on our new peer-reviewed paper:

The pandemic is as bad as it ever was for babies - in year to Aug 2023, 6,300 babies under 1 were admitted to hospital wholly or partly BECAUSE of Covid.

They are ONLY age group where admissions have NOT gone down over time 1/17 Image
Our study, led by Prof @katebrown220, looked at all hospitalisations in England in children with a Covid diagnosis or positive test from Aug 2020-Aug 2023.
We then *excluded* all admissions where a Covid diagnosis was incidental (ie not why they were in hospital)
2/17 Image
Infants (babies under 1) are generally at higher risk from respiratory infections, plus they are the age group that, if infected, are overwhelmingly meeting the virus for the first time.

They are not vaccinated and have not had it before. 3/17
Read 18 tweets
Sep 26
Prof @Kevin_Fong giving the most devastating and moving testimony to the Covid Inquiry of visiting hospital intensive care units at the height of the second wave in late Dec 2020.

The unimaginable scale of death, the trauma, the loss of hope.
Please watch this 2min clip.
And here he breaks down while explaining the absolute trauma experienced by smaller hospitals in particular - the "healthier" ICU patients were transferred out, leaving them coping with so much death.

They felt so alone.
Here Prof Fong explains how every nurse he met was traumatised by watching patients die, being only able to hold up ipads to their relatives and how it went against their normal practice of trying to ensure a dignified death, with family there.
Read 5 tweets
Aug 28
THREAD: I asked what the point of Public Inquiries is for @bmj_latest

We've spent hundreds of millions of £ on Inquiries over last decades, generating deep understanding of failures & 1000s of recommendations.

But v few recommendations get implemented!
What is going on?

1/12 Image
E.g. Covid-19 Inquiry has cost £94 million so far - and is projected to cost over £200m by its end (it still has years to go).

1st report published (out of at least 9) found major flaws and proposed 10 recommendations.

Chances are low that they will be implemented :-( 2/12


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Inst for Government looked at 68 Inquiries from 1990-2017.
The Inquiries cost over £630 million and made 2,625 recommendations.

Only 6/68 Inquiries have received full scrutiny by a parliamentary select committee on implementation of recommendations. 3/12 Image
Read 12 tweets
Aug 9
🧵War causes direct civilian deaths but also indirect deaths over the following years.

Recent paper estimates eventual total direct & indirect deaths in Gaza attributable to the war - 10% of entire pop'n.

I want to explain these estimates and why deaths must be counted. 1/13 Image
Why count casualties from war anyway? For moral, legal and strategic reasons.

1 - owe it to those who have died
2 - International law says must count & identify dead as far as possible
3 - monitor progress of war & learn from tactics

2/13 Image
There are direct and indirect casualties of war. Direct deaths include those who killed by fighting or bombs.

Indirect deaths are those that die when they would otherwise have lived because of one or more of: lack of food, healthcare, housing, sanitation, income, hope. 3/13 Image
Read 14 tweets
Aug 1
THREAD: the summer Covid wave in the UK continues.
Basically, there is a LOT of Covid around and not a lot of other respiratory viruses.

If you have cold or flu symptoms, it's probably Covid.

The latest hospital data from England shows steady, quite high levels. 1/8 Image
But admissions don't tell us how much virus is circulating more generally. The best (but imperfect) measure we have is wasterwater measurements, and only in Scotland and not England.

Scotland's wastewater is showing a huge July peak - highest since Omicron's 1st yr in 2022 2/8 Image
Because different people shed different amounts of virus and variants can matter too, you can't for sure infer how many people were infected between different wasterwater peaks. BUT given the size, I'd say it's pretty likely this is the largest peak since 2022 in Scotland 3/8
Read 8 tweets
Jul 23
THREAD:
I wrote about Baroness Hallett's Inquiry Module 1 report for @bmj_latest .

She found that there was *never* a plan to keep a pandemic death toll down - I discuss this and what it means going foward.

Main points below: 1/14 Image
The headline most seen is that the UK planned for the wrong pandemic.

While it is true that was far too narrow a focus on a flu pandemic, that is not the most telling bit.

To me the most telling bit, is what the plan did NOT do 2/14


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The issue is less the wrong disease, but that there was never a plan to prevent one at all – of any disease type.

The plan was *never* about reducing the number of pandemic deaths. 3/14 Image
Read 14 tweets

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