The questions in this letter are not specific or productive if directed at the leaders of NIH/NIAID.

The priority should be to secure a commitment from NIH/NIAID to publicly release the Feb 4, 2020 draft of Proximal Origin and the fully unredacted emails.
republicans-oversight.house.gov/wp-content/upl…
None of the 7 questions ask specifically what the perceived competing interests in the Feb 1 group are, ie, what the impact of a lab #OriginOfCovid would be on the participants' careers and reputations; why several contributors went completely unacknowledged in Proximal Origin.
None of the 7 questions ask specifically what corrective actions should be taken while this issue is being resolved, eg, editor's note on Proximal Origin, recusal of Feb 1 participants from all academic/advisory activities relating to #OriginOfCovid
None of the 7 questions ask for an immediate commitment to revamp the review & publication system for pathogen research so that it is made much more transparent and accountable.

None of the questions ask for a commitment to release all docs relating to SARS-like virus research.
None of the questions ask specifically what should be done by NIH/NIAID if the EcoHealth Alliance fails to produce documentation of the collaborative research on novel pathogens, whether in Wuhan, China or any other country.

*EcoHealth continues to be funded by NIAID today.
None of the questions ask specifically if NIH/NIAID personnel have, after the Feb 1 call, continued to discourage discussion and actions in the scientific community or in government to transparently investigate a lab #OriginOfCovid
For instance, have there been more meetings or emails where NIH/NIAID personnel were involved and either acted to or witnessed attempts to suppress discussion, data sharing, and/or publication of analyses relating to the beginnings of the pandemic?
In my opinion, the 7 questions in the letter are mostly throwaways with very predictable responses that we have already seen the Proximal Origin authors & friends use in social media and in news interviews.
republicans-oversight.house.gov/wp-content/upl…
Answers to Questions 1-3:
We were in the process of science, and didn't sound the alarm to avoid panic/distraction till we were very confident that the #OriginOfCovid was most likely natural, ie, when Proximal Origin was published.
Answer to Question 4:
Might honestly be no edits to Proximal Origin were made by NIH/NIAID leaders. Just feedback in emails.

This is a throwaway question. Better to ask for the manuscript drafts that were being exchanged via email.
Answer to Question 5:
Probably no impact.
Answer to Question 6:
Possibly no.

Both questions 5 and 6 distract from or undermine the inquiry to obtain more information about the Feb 1 phone call and Proximal Origin.
The last question is an open invitation for deflection.

There are several people with degrees who assert that knowing SARS-CoV-2 could've come from a lab would've changed nothing in the global early response to the novel outbreak.
I can't watch any more hearings or sessions where non-productive or incoherent questions are asked.

What happened yesterday was counterproductive to getting a better understanding of how an investigation into a potential lab #OriginOfCovid was suppressed for more than a year.
At the end of the day, the biggest questions are:

How should we investigate the plausible hypothesis that SARS-CoV-2 may have emerged from research activities by a group that had received US funding for similar projects? What actions must be taken now to prevent lab outbreaks?

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More from @Ayjchan

12 Jan
I'm all ears to hear about the precise scientific process that occurred between Feb 2 and Feb 4, 2020 where top experts in virology and evolutionary biology completely changed their minds about the likelihood of SARS-CoV-2 emerging from a lab.
In Jeremy Farrar's book, he noted that Marion Koopmans had said furin cleavage site insertions happen in viruses all the time naturally.

Kristian Andersen, lead author of Proximal Origin, said just because it happened in nature did not rule out unnatural origins.
By the time Proximal Origin was published (i.e., the final paper), Koopmans argument had been absorbed into the manuscript without acknowledgement.

"insertions.. can occur.. the polybasic cleavage site can arise by a natural evolutionary process."
nature.com/articles/s4159…
Read 8 tweets
11 Jan
Transcripts of the early 2020 exchanges on the #OriginOfCovid among leading scientists in the US & Europe show they were privately worried about a lab origin of Covid-19.

Yet, publicly they authored Proximal Origin, which dismissed lab origin hypotheses.
republicans-oversight.house.gov/wp-content/upl…
In private, they understood that "the only people with sufficient information or access to samples to address [the #OriginOfCovid] would be the teams working in Wuhan."

In public, they wrote "we do not believe that any type of laboratory-based scenario is plausible."
The day (Feb 4, 2020) that a first draft of Proximal Origin was shared with Fauci and Collins by Farrar, Farrar said Edward Holmes (one of the Proximal Origin authors) had guessed 60:40 lab and Farrar guessed 50:50.
Read 23 tweets
11 Jan
Peter Daszak asked for US-funded virus data to be withheld, FOIAed by @USRightToKnow

"It's extremely important that we don't have these sequences as part of our PREDICT release.. Having them as part of PREDICT will being very unwelcome attention"
usrtk.org/wp-content/upl…
@USRightToKnow Only way to know if some of these virus sequences are completely new and still not public is for NCBI database or PREDICT to release the data.
@USRightToKnow The FOIA process is so protracted that we're only seeing April 2020 emails in Jan 2022. And there are many, many more FOIAs and appeals against redactions still ongoing for emails from 2020.

See the longer list of FOIAs by the @USRightToKnow here:
usrtk.org/biohazards-blo…
Read 5 tweets
8 Jan
Stories of Covid-19 whistleblower doctors, journalists & scientists - disappeared, imprisoned, penalized, maltreated, slandered as rumormongers - doesn't inspire confidence that the world will get a timely alert the next time a mysterious outbreak appears.
cnn.com/interactive/20…
These reports are old, but the problem persists.

How can global pandemic response be rapid if there are countries where alerting your hospital colleagues to a novel outbreak and telling them to wear protective equipment results in punishment?
theguardian.com/world/2020/mar…
I don't think it is a misstatement to say doctors were being brutally silenced when they blew the whistle on the earliest Covid-19 cases. Several lost their lives in this process after being forced to sign confessions and returning to fight the outbreak.
Read 4 tweets
6 Jan
The balance of evidence for a natural vs lab #OriginOfCovid is different from that of Omicron.

In the case of Omicron, many known plausible natural sources of the novel variant.

In the case of the original SARS-CoV-2, only postulated natural sources, no direct evidence found.
The case for a wet market #OriginOfCovid remains dimly lit. Lack of access to data describing what potential intermediate hosts were even sold at Huanan market in late 2019. Lack of access to early case data and exposures to potential sources of the virus.
Sorry to disappoint some natural origin diehards, but not all people who think a lab #OriginOfCovid is plausible are going to think Omicron likely came from a lab.

You have to evaluate the evidence and circumstances specific to each emergence.
Read 5 tweets
4 Jan
I'm aware of the @newrepublic review of our book VIRAL: The Search for the Origin of Covid-19. I don't have much to say about it because it isn't a review of VIRAL. It was an opinion on #OriginOfCovid dressed up as a book review.

See article by @thackerpd
disinformationchronicle.substack.com/p/get-the-hell…
In order to formulate a response in defense of the book, there must be facts-based criticisms of the book's content, which do not exist in the @newrepublic review.

So how should I respond to a negative review that goes after the same old strawmen not represented in the book?
@newrepublic One scientific scenario I can compare this to is when you get a peer reviewer who clearly has a vendetta against a particular hypothesis. Instead of critiquing the data in the paper, goes after old arguments by other scientists, recommending rejection of the manuscript at hand.
Read 4 tweets

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