1/ The pandemic has felt endless, so the beginnings seem like a distant memory. Does anyone remember the worst-case model of 1.5-2.2m deaths that the White House used to “shock and awe” in March ’20?
To date, there have been 864k deaths in the US.
A look back below🧵
2/ Before this press conference, Trump compared COVID to the flu with only “22 deaths”, “life & the economy go on.”
Sound familiar?
If only the current death rate — with all of the advantage of our vaccines and therapeutics — were as low as the flu today.
3/ The current 7-day average of COVID deaths is 2k+/day with yesterday's number of 3,866 deaths being one of the worst days ever during the pandemic.
At this rate, this is a 20-50x difference from what the average flu season is like!
4/ Going back to early 2020, there were strong reactions to this WH prediction of hundreds of thousands of deaths.
I’ll never forget @MikeFrancesa’s reaction at the time. Worth a listen if you didn’t hear it:
5/ There were of course naysayers who said that the projections were overblown, even inside the White House.
6/ While the Trump administration could have saved more lives, the same could be said for Biden’s first year where more people have now died (400k+) than during the Trump era.
IMO, there is plenty of blame to go around for preventable deaths.
7/ The lack of national unity in promoting vaccines in late 2020 after the election was a missed opportunity, which likely contributed to vaccine hesitancy throughout 2021.
8/ Would it be shocking for deaths to reach the worst case scenario of 1.5m+ deaths?
Yes it would, but we could reach that shocking milestone by 2023 if the mortality rate doesn’t improve from the 1,500-2,000 daily deaths the US has averaged over the last several months.
9/ We all welcome the arrival of the oral therapies as the silver bullet, but we have had other "savior" therapies to reduce mortality that did not exist in March 2020 — remdesivir, dexamethasone, convalescent plasma, monoclonal antibodies.
And yet here we are.
10/ Unless something materially changes, we have considerably more disease burden ahead. There are >100 million under-vaccinated and immunocompromised people in the United States, which is a very large pool of susceptible people at risk of death.
11/ With the failure of the federal vaccine mandate and a pretty dug in group of people who will never get vaccinated, we may be stalemated as a society where we have to grow used to a “new normal” of excess death.
12/ As we approach the two-year mark of this White House press conference, I wonder if there is a Deborah Birx in the current administration who has second thoughts about our current path forward.
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1/ Japan has fared better throughout COVID than most western countries (146 deaths/million vs. 2,590 deaths/million in the US) despite:
- Very low public trust in gov’t
- Less trust in science
- No mandates
2/ This trope around Confucius societies “winning the COVID-19 war” with “authoritarian mentalities” doesn’t neatly apply to Japan where only 4% of people surveyed in 2020 say they trust the government “a lot”, compared to 9% in the US and 12% in the UK.
My ten “surprises” in healthcare for 2022 — events that the average person would only assign a one out of three chance of taking place but which I believe have a better than 50% likelihood of happening. Styled after Byron Wien’s annual predictions. 🧵
#1: There is at least one new variant that emerges in 2022 that drives another omicron-sized surge of cases and hospitalizations, putting renewed stress on the healthcare system.
#2: Employers capitulate in mandating in-person return-to-work (with a few notable exceptions) for 2022. A widely distributed workforce enhances the value proposition of national, scaled healthcare players and virtual solutions.
1/ Even with the Supreme Court invalidating the Biden vaccine mandate, large companies are likely to take matters into their own hands with “sticks” (versus “carrots”). Even with a “mild” variant, economic consequences are significant enough to impact corporate behavior 🧵
2/ With hospitalizations surging (with fewer deaths) among the unvaccinated, the bill will come due at some point — to the tune of $20,000+ per hospitalization.
3/ Beyond hospitalization costs, the higher case rates of unvaccinated people have implications for productivity loss due to absence along with short-term disability costs. Chart below shows the trend for NYC.
1/ With the omicron wave putting untold pressure on staffing across a wide variety of industries, it is not inconceivable for these staffing shortages to become more “endemic” with behaviors that have likely changed forever. 🧵
2/ An estimated 5 million people are isolating at home due to omicron, which could “deal a significant hit to the economy over the next month or two.”
3/ In historical flu seasons, the current omicron-driven work absentee rate would be ~2x the average peak of workplace absence due to all illnesses in the US (largely flu).
1/ One of the biggest policy failures over the last 2 years is the lack of COVID testing, particularly evident now with omicron — both the supply and the quality of what we have available at scale. Where is our Operation Warp Speed for diagnostics? 🧵
2/ Based on the sheer scale of testing volume, it’s clear many are concerned with exposure to omicron and are not yet “done with COVID”. Labs are reporting >1.5 million PCR tests per day right now. But this is a massive underestimate of the total volume w/antigen tests in the mix
3/ Based on recent disclosures, the leading antigen test kit mfg. production volumes right now are estimated to be ~120 M tests/month