Thread by @AndrewEwing11

1/36 Update of the covid and the brain talk I recently gave to Drs at Select Medical
Better quality figures
More on references to look up: Lancet, NEJM, Nature, Neurology, etc
Some new material dispersed and at end
Some thoughts on possible treatments (not my expertise)

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19/36 A hallmark of Parkinson's disease.

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30/36 Note, this could also be caused by the intense ventilation as no control for that, but 10 of 10 age 58 and below showed this.

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35/36 There is some hope. And this is only a small sampling of ideas out there.

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To clarify, the figure to the left shows mechanisms discussed in May 2020. Now know olfactory nerves do not have ACE2 but blood vessel damage likely. More on next slide.
Right: some of the recent evidence that Sars-cov2 enters the brain, but distal and inflammatory entry too.

37/ This is a small sampling, but an important alert just out that covid can be causing damage to children's brains (as some of my slides indicate) and cause convulsions. Important work and much more needs to be done.

https://twitter.com/ludvigsson/status/1488071944633298944

Add this to slides 30 & 31 on amyloid deposits. Still not sure but if this is correct and in high percentage of infected, it will not be good.

https://twitter.com/EricTopol/status/1488637332689342468

More
Seems covid causes loss of brain grey matter (the part dense w our all-important nerve cells; see my pinned thread) and now long covid with inflammation can cause it to swell. Both outcomes are very bad.
sciencedirect.com/science/articl…

A new thread with more references.
Posted here to complete the loop for those looking at either thread and not the other.

https://twitter.com/AndrewEwing11/status/1586500342841475072