Lots of talk of wearing masks.
The policy question is: what happens when you advise people to:
Wear cloth masks
Wear surgical
Wear n95s
You have to combine mask properties with real world compliance
Ans:
No benefit
11% benefit in setting w no immunity & high bias rct
No trial
The policy question is: what happens when you advise people to:
Wear cloth masks
Wear surgical
Wear n95s
You have to combine mask properties with real world compliance
Ans:
No benefit
11% benefit in setting w no immunity & high bias rct
No trial
The 11% benefit should have an* because there is a serious risk of concealment being revealed in the study due to imbalance and study population by arm
If you pair this imbalance with the idea that people will be slightly less likely to report symptoms if they were enrolled on the margin. You have a big problem
There's also a missing endpoint of that study. Random sero prevalence. It's the most biased resistant endpoint so it's a shame it's not yet been reported
After vaccination, the entire calculation changes. You've already maximally reduced your risk of bad outcomes. When you are infected. You can never avoid infection forever. So the entire point is null.
But that's assuming that you'll actually get good compliance. But you probably won't get good compliance because nobody wants to do this anymore.
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