THREAD - STATE OF COVID IN UK

Quite long but hopefully comprehensive thread on where we are...

TLDR: cases increasingly hard to interpret, hosp & deaths declining, schools big issue, new (but not more severe) subvariant growing 1/18
Vax - vaccinations have dropped off a cliff in 2022. 80K a day vs almost 1 million before Xmas.

And it's not cos we've finished! Esp NI has only 50% of pop boosted.

We need to keep trying to increase uptake - messaging that pandemic is over and omicron mild doesn't help. 2/18
PCR tests have dropped off massively too since we've stopped requiring confirmatory tests for LFDs. *Reported* use of LFDs is also dropping.

Some is less infection, but not all. Will make both reported cases & positivity rate (based on PCR) hard to interpret. 3/18
NI calcs +ve rate differently now so is on separate plot.

Positivity and cases are now flat for all nations except NI.

Since 31st NI & England reporting reinfections >90 days after 1st, Wales >42 days after 1st and Scotland not yet... 4/18
Can see (approx) impact of adding known reinfections in England here - the increase in reinfections with Omicron is clear -> ~10% of cases each day.

It's great that UKHSA have added them now, but with Omicron it's possible 90 days is too long an interval... 5/18
Reported cases suggests Scotland & Wales back to Nov levels, but ONS infection survey says nowhere near & that scot & wales going up.

Meanwhile, Zoe symptom tracker app says cases back to peak levels. Each measuring diff thing over diff timescale but usually consistent. 6/18
So cases are still *v high* but trend hard to interpret. Hospitalisaitons are going steadily down which is good.

That said, NHS staff absences are still much higher than last 2 yrs so still a lot of pressure in terms of staffing as well as higher occupancy than autumn. 7/18
In terms of death, deaths by day reported went over 500 this week which caused lots of misleading reporting. Need to look at 7-day avgs *and* numbers by date of death (a bit lagged).

Deaths seem to have peaked ~300 a day - still high! but nowhere near 500. 8/18
So what is on horizon? Well, Omicron has 3 main types: BA.1 (main one in UK), BA.1.1 (daughter of BA.1) & BA.2 (sibling of BA.1).

BA.1.1 seems to outcompete BA.1 and BA.2 outcompetes both. 9/18
Denmark has higher vax rates than us & BA.2 now dominant - v high cases (equiv to >600K a day here!).

But while deaths & admissions are rising, they are in line with less severity (given case numbers!). ICU cases are falling still. So BA.2 prob no more severe than BA.1 10/18
In England, BA.1.1 has been taking over from BA.1, but now BA.2 seems to be outcompeting both.

BA.2 most prevalent in N Ireland (which has high case growth now!) & London & SE in England. 11/18
While on variants, ONS released analysis of chance of symptoms (on day of test only - symptoms could be over or still to come).

Both Delta & Omicron more likely to cause symptoms than Alpha *and* 2nd infections just as likely to have symptoms as 1st Delta infections. 12/18
And then... children & schools. Dashboard says cases in kids & parents' generation flat or declining. Zoe app says they are going up.
ONS infection survey shows cases 2x higher in primary than secondary and high.
Next week's ONS will show whether case trend up or down. 13/18
And these high infections have consequences. Admissions in children stay stubbornly (relatively) high with Omicron - and data suggests Omicron is *not* milder for kids.

Plus Long Covid has been going up in kids & school staff. 14/18
ONS also released vaccination updates this week.

Firstly, vaccinations in teens is still much lower than in adults - esp second doses.

Secondly, rates are much lower in schools in more deprived areas. 15/18
For teenagers who had been vaccinated, most common reason was to protect others and then themselves.

So, although JCVI do not consider benefits to others in their decisions on child vax, it's worth noting that teens do consider it.

Also, most parents would vax 5-11 yrs. 16/18
And finally - ventilation! almost third of schools said that good ventilation was hard to implement.

Half said not enough CO2 monitors, and 10% of CO2 monitored rooms had poor readings and no way of improving. 17/18
Accepting that the virus is airborne is vital to learning to adapt to Covid - that means we need to understand mask use & how we make air cleaner.

So please do watch this discussion in Indie SAGE today with @trishgreenhalgh & @adsquires! 18/18
PS thanks to Bob Hawkins as ever for his help with getting some of the data & plots!

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More from @chrischirp

Oct 19
Important 🧵on our new peer-reviewed paper:

The pandemic is as bad as it ever was for babies - in year to Aug 2023, 6,300 babies under 1 were admitted to hospital wholly or partly BECAUSE of Covid.

They are ONLY age group where admissions have NOT gone down over time 1/17 Image
Our study, led by Prof @katebrown220, looked at all hospitalisations in England in children with a Covid diagnosis or positive test from Aug 2020-Aug 2023.
We then *excluded* all admissions where a Covid diagnosis was incidental (ie not why they were in hospital)
2/17 Image
Infants (babies under 1) are generally at higher risk from respiratory infections, plus they are the age group that, if infected, are overwhelmingly meeting the virus for the first time.

They are not vaccinated and have not had it before. 3/17
Read 18 tweets
Sep 26
Prof @Kevin_Fong giving the most devastating and moving testimony to the Covid Inquiry of visiting hospital intensive care units at the height of the second wave in late Dec 2020.

The unimaginable scale of death, the trauma, the loss of hope.
Please watch this 2min clip.
And here he breaks down while explaining the absolute trauma experienced by smaller hospitals in particular - the "healthier" ICU patients were transferred out, leaving them coping with so much death.

They felt so alone.
Here Prof Fong explains how every nurse he met was traumatised by watching patients die, being only able to hold up ipads to their relatives and how it went against their normal practice of trying to ensure a dignified death, with family there.
Read 5 tweets
Aug 28
THREAD: I asked what the point of Public Inquiries is for @bmj_latest

We've spent hundreds of millions of £ on Inquiries over last decades, generating deep understanding of failures & 1000s of recommendations.

But v few recommendations get implemented!
What is going on?

1/12 Image
E.g. Covid-19 Inquiry has cost £94 million so far - and is projected to cost over £200m by its end (it still has years to go).

1st report published (out of at least 9) found major flaws and proposed 10 recommendations.

Chances are low that they will be implemented :-( 2/12


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Inst for Government looked at 68 Inquiries from 1990-2017.
The Inquiries cost over £630 million and made 2,625 recommendations.

Only 6/68 Inquiries have received full scrutiny by a parliamentary select committee on implementation of recommendations. 3/12 Image
Read 12 tweets
Aug 9
🧵War causes direct civilian deaths but also indirect deaths over the following years.

Recent paper estimates eventual total direct & indirect deaths in Gaza attributable to the war - 10% of entire pop'n.

I want to explain these estimates and why deaths must be counted. 1/13 Image
Why count casualties from war anyway? For moral, legal and strategic reasons.

1 - owe it to those who have died
2 - International law says must count & identify dead as far as possible
3 - monitor progress of war & learn from tactics

2/13 Image
There are direct and indirect casualties of war. Direct deaths include those who killed by fighting or bombs.

Indirect deaths are those that die when they would otherwise have lived because of one or more of: lack of food, healthcare, housing, sanitation, income, hope. 3/13 Image
Read 14 tweets
Aug 1
THREAD: the summer Covid wave in the UK continues.
Basically, there is a LOT of Covid around and not a lot of other respiratory viruses.

If you have cold or flu symptoms, it's probably Covid.

The latest hospital data from England shows steady, quite high levels. 1/8 Image
But admissions don't tell us how much virus is circulating more generally. The best (but imperfect) measure we have is wasterwater measurements, and only in Scotland and not England.

Scotland's wastewater is showing a huge July peak - highest since Omicron's 1st yr in 2022 2/8 Image
Because different people shed different amounts of virus and variants can matter too, you can't for sure infer how many people were infected between different wasterwater peaks. BUT given the size, I'd say it's pretty likely this is the largest peak since 2022 in Scotland 3/8
Read 8 tweets
Jul 23
THREAD:
I wrote about Baroness Hallett's Inquiry Module 1 report for @bmj_latest .

She found that there was *never* a plan to keep a pandemic death toll down - I discuss this and what it means going foward.

Main points below: 1/14 Image
The headline most seen is that the UK planned for the wrong pandemic.

While it is true that was far too narrow a focus on a flu pandemic, that is not the most telling bit.

To me the most telling bit, is what the plan did NOT do 2/14


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The issue is less the wrong disease, but that there was never a plan to prevent one at all – of any disease type.

The plan was *never* about reducing the number of pandemic deaths. 3/14 Image
Read 14 tweets

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