Andrew Sanchez Profile picture
Feb 9, 2022 13 tweets 8 min read Read on X
Compendium of ECG findings concerning for ☠️♥️occlusive MI ♥️☠️ (1/11)
First, back to basics & traditional STEMI criteria! Here's a nice figure of Lead Anatomy. I saved this forever ago, so not exactly sure of the source ¯\_(ツ)_/¯

(2/11)
STEMI criteria is met if: STE at least 1mm in 2 contiguous leads, but with higher cut-offs in V2-V3, & with addition of new LBBB in setting of compatible clinical picture. You can localize the coronary lesion using the leads affected! Localization chart by @DrEricStrong (3/11)
Before going into "STEMI equivalents" (better phrasing: "occlusive MI amenable to revascularization"), here's a figure from @LITFLblog on the J-point, which will be referenced later in the thread!

Occlusive MI: hqmeded-ecg.blogspot.com/2018/04/the-om…

J-point: litfl.com/j-point-ecg-li…

(4/11)
OK, here is ♥️De Winter's T Waves♥️, concerning for proximal LAD lesion! Great thread on this pattern here:

(5/11)
Next, ♥️Wellens' Syndrome♥️, a clinical syndrome characterized by biphasic or deeply inverted T waves plus a history of recent chest pain now resolved. The progressive T wave changes can be understood as follows: litfl.com/wellens-syndro…

(6/11)
Speaking of anterior MIs, a higher level concept that should be more widespread involves ☠️Terminal QRS Distortion☠️, defined as the absence of S-wave & J-wave in either V2/V3. Such distortion suggests Subtle Anterior MIs! @smithECGBlog

hqmeded-ecg.blogspot.com/2022/02/this-e…

(7/11)
♥️ First Diagonal Occlusion ♥️ presents with a fun pattern called the South African Flag Sign! An easy way to remember this is the upper leads (on ECG strip, not anatomical leads) have upward changes (STE & upright T waves), while lower leads have downward changes.

(8/11)
♥️ Posterior MI ♥️: horizontal STD in V1-V3 & upright T waves in V1-V3.

However, STD maximum in V1-V4 can also be due to subendocardial ischemia (not occlusive MI) when there is tachycardia, especially if due to AFib with RVR.

See: hqmeded-ecg.blogspot.com/2021/11/is-thi…

(10/11)
Fin! Corrections appreciated! I'M A LOWLY INTERN & AM NOT PRETENDING TO KNOW 50% OF THIS IN DETAIL!

However, if you are trying to up your ECG game, follow: @smithECGBlog @EM_RESUS. For basics to advanced, check @DrEricStrong's Youtube series.

(11/11)

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More from @ASanchez_PS

Nov 27, 2024
🫧 Approach to Blistering Skin Disorders 🫧

What? → Fluid-filled skin lesions occurring by 1 of 3 mechanisms:

1. Acantholysis

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The key pivot of this schema emphasizes a search for exogenous culprits of life-threatening disease, as these culprits must either be treated or avoided in the future.

🚨 This classification is very imperfect (e.g. numerous SJS/TEN cases are idiopathic) 🚨 Image
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🟡 Monoclonal Gammopathies of Renal Significance (MGRS)! 🟡

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Let's re-do MGRS. Image
Newcomer to the land of monoclonal gammopathies of clinical significance (MGCS)?

Check out the original thread on MGCS here 👇, then read on!

So, MGRS. How do we even get to this space? 🗻

Recall from my prior thread on Paraprotein testing that one path to sending these tests is based on suspicion for a Paraprotein-mediated disorder; namely, the Plasma cell dyscrasias & MGCS diseases.

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It's been a while, #MedTwitter!

Today, @Gurleen_Kaur96, @Mark_Heslin, & I bring you our diagnostic approach to myocarditis.

First we'll give a lay of the HFrEF land; then, we'll cover presenting features & Endpoint DDx.

Onward! Image
The "diagnostic arc" of HFrEF 🏔️

Lots of ways to break down the assessment of new HFrEF... Here's how we do it:

☠️ 1st Pass = Base Rate/Sick

- Ischemic cardiomyopathy reigns in the elderly & at-risk: ECGs should be scrutinized for signs of occlusive MI & pathologic Q waves👇 Image
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📚 Note: while stress-induced CM is often suspected by clinical picture, left heart catheterization +/- cardiac MRI is needed to exclude OMI & other diseases. Image
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Rising #MedTwitter #MedX interns, here are my favorite approaches for acute inpatient medicine issues! 🚨

1) Hypoxemia, by @ClementLeeMD 🫁

Ditch the alveolar gas equation (sorry @PulmPEEPs) & use this practical approach.

✍️ Dr. Lee's approach is summarized by @MatthewHoMD here, with Dx/Rx considerations by @Sophia_Hayes_MD.

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🩸 Paraprotein Evaluation 🩸

SPEP, SIFE, SFLC, UPEP, UIFE.

What do these abbreviations mean & how does one arrive to the land of paraproteinemias?

Here is a tweetorial for the internist diagnostician, in collaboration with @cullen_lilley! Image
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⚪ ↑ immunoglobulins (antibodies)

⚪ ↓ albumin

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Read 27 tweets
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"Auto-antibody Craze" DDx 🔥

A short list of 🦓 diagnoses tied together by a rare, confusing disease signature.

Here's a super brief tweetorial. Image
Signature ✍️

- Variable auto-antibody positivity → polyclonal hypergammaglobulinemia & autoimmune disease

- B-symptoms +/- LAD

What do I mean by variable auto-antibody positivity? Just take a look at these labs 👇 Image
They're all over the place!

Here are some diseases that can do this...
Read 14 tweets

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