Giuseppe Galati Profile picture
Apr 2 โ€ข 6 tweets โ€ข 13 min read
๐ŸŽ– #ACC_AHA_HFSA #HF Guidelines are out
Short Tweetorial
๐Ÿ€ Congrats to the authors for the huge effort : 108 pgs covering multiple aspects including #CardiacAmyloid
@ShelleyZieroth @hvanspall @carlosguizars @ValleAlfonso @JavedButler1 @gcfmd @JJheart_doc
rb.gy/ocnlb7
1๏ธโƒฃ #HFrEF tx
โœ… Pros: Clear 4 pillar 1st line 1 day ( No wait)
โŒ Cons: NYHA is not fixed very changeable : Better using Hypotension (SBP<100 mmHg) as choice criteria for ACE/ARB vs ARNI
โŒ Cons: After 1 + 1/2 year from #GALACTIC_HF Omecamtiv Mecarbil still not in GD
2๏ธโƒฃ #HFmrEF
โœ… Pros: Concur with HFmrEF recom.
โญ•๏ธ Probably a 2a in this class for #ARNI is more EBM
@DrNasrien @dranulala @robmentz @MicheleSenni @DrDEliaEmilia @gbiondizoccai @torresviera @JavierdeJuan1 @global_meded @Filippatos @YuriLopatin1
#ACC22
3๏ธโƒฃ #HFpEF
โœ… #SGLT2i in
โŒ Cons: Diuretics Class I (No RCT, This are GD on #HF not on #Hypertension) very questionable
โŒ Especially when #EMPEROR_PRESERVED (~ 6000 pts RCT) positive & only 2a?
Because not significant on #CV_Death? ๐Ÿฅถ
Someone is missing the point in #HFpEF
4๏ธโƒฃ A major paradigm shift should be done in #HFpEF
๐Ÿ€ These pts are very old at diagnosis (76 mean age in ๐Ÿ‡ฎ๐Ÿ‡น & in all registries over the last 15-20 yrs)
๐Ÿ€ Mean expectancy of life from diagnosis to death in mean 6-7 year
๐ŸŽฏ Our target is โฌ†๏ธ #QoL & โฌ‡๏ธ #HHF
@ShelleyZieroth
5๏ธโƒฃ Final
๐Ÿ”ฅ Rita Levi Montalcini : Nobel Prize 1986 โœ… โ€œBetter adding life to days than days to lifeโ€
๐Ÿ‘Œ Perfect for #HFpEF
๐Ÿ€#SGLT2i Class I
๐Ÿ‘‰ โ€œScience go faster than guidelinesโ€
๐Ÿ€ next year new #GD
๐Ÿ€ My hope high-time for TransAtlantic GD ACC_AHA_HFSA/ ESC_HFA
@DLBHATTMD

โ€ข โ€ข โ€ข

Missing some Tweet in this thread? You can try to force a refresh
ใ€€

Keep Current with Giuseppe Galati

Giuseppe Galati Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(