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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
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Apr 24 • 4 tweets • 2 min read
Data form @NSWHealth showing #Flu (a bit early for that trajectory) taking a steep upwards turn now. Adenoviruses (normal but steep), MPV (way early) and RSV (a bit late) doing the same. Plenty of picornavirus (RVs and EVs) activity as well.
health.nsw.gov.au/Infectious/cov…
I wonder if, after this flu season, the "normal" respiratory virus seasonality patterns will return. Would be nice to see a similarly drawn SARS-CoV-2 graph here now @NSWHealth . I do wonder how it's contributing to virus:virus interaction at a community level
Up in Queensland (still east coast of Australia), FluA, RSV and AdVs, RVs declining. SARS-CoV-2 % holding. Data from one of our latest private pathology labs (Sullivan Nicolaides Pathology)
snp.com.au/clinicians/rep…
A number of locations need to get their flu reporting going by the way.

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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture

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More from @MackayIM

ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
Apr 25
Can't yet find any #Flu genotyping data for Aus (reporting only starts during "flu season").
So this is what our local southern hemisphere vaccine is composed of. Hopefully, it includes what's circulating.
From: tga.gov.au/media-release/… Image
Good old @nextstrain (I must be rusty) shows that the most recent FluA/H3N2s (Flu's slipperiest "big bad") - reported from Australia - fall within the A/H3N2 3C.2a1b.2a.2 clade (yellow arrow) Image
Couple of things to note:
🦠both (egg-grown and cell-grown) A/H3N2 vaccines use strains within the same clade, a little older, but look like a good vaccine "match"
🦠very little A/H1N1 strain, B/Victoria or B/Yamagata lineage activity in Aus atm
Read 4 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
Apr 23
4 people tragically died in car accidents over the Easter weekend in New Zealand.
50 people died from COVID-19 over that same period in NZ.
Hopefully, there were equivalent "tragic loss of life" media stories.
◾️rnz.co.nz/news/national/…
◾️covid19.who.int/region/wpro/co…
In Queensland, Australia (population ~1.02x NZ's), there was 1 Easter road death and 7 COVID-19 deaths.

◾️stats.govt.nz/topics/populat…
◾️mypolice.qld.gov.au/news/2022/04/2…
In New South Wales, Australia, (popn ~1.60x NZ's), there were 7 road deaths and 44 CPOVID-19 deaths.
◾️abc.net.au/news/2020-03-1…
◾️abs.gov.au/statistics/peo…
Read 11 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
Mar 16
When we decide "the pandemic is over", we'll of course also have decided on additional permanent funding, staffing & support ...right?
Because hospitalisations are neither free, absorbable, & without harm to loved ones & patient families.
All require new💲&👩‍⚕️
ping @who
These hospitalisations are neither plummeting nor have they returned to zero. Even in a well-vaccinated country, like Australia, the baseline of hospital illness has been raised and has been fairly stable as we drop all our NPIs. Roll on the southern winter I guess.
And what do those vaccinations look like here?
Nationally we're at 81% double-doses but only 48% triple dosed. Most of the double dosing happened in Aug-Oct 2021. We're in 6-month territory now.
REALLY good time to get that booster (=3rd dose) if you haven't already.
Read 8 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
Feb 13
"Opening up" had to happen at some point.
That *should* have been after everyone wanting 3-doses of vaccine had had them.
But even that won't stop transmission.
Sadly, severe disease and death will still follow in some people for a range of reasons, but at a *vastly reduced* level compared to the unvaccinated 'let it rip' waves that took so many lives in so many places.
To reduce risk further, we can ensure measures to reduce transmission of this (and other sometimes deadly) airborne virus which occurs mainly through the exhalation of aerosols from an infected person; from singing, to coughing, to puffing to just breathing out.
Read 6 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
Jan 28
I'd have liked us to wait longer to better understand Omicron before opening up. I'd have liked us to spend more time to educate about masks and upgrade to better masks. I'd have liked us to explain how RATs have use, but also weaknesses.
I'd have liked us to have been honest about the lives we'd lose. I'd have liked us to have rolled out filtration in schools, workplaces and shops these past years. I'd have liked us to explain what the next goal was after 2 doses of vaccine.
I'd have liked us to show some sign we'd learned anything from this. I'd have liked us to talk about lives that could be saved & harm prevented due to reducing other airborne viral infections. I'd like us to acknowledge that we can achieve great change.
Read 4 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻🧙‍♂️ Profile picture
Dec 30, 2021
It is what it is.
In Aus, where the leadership mindset changed to one of something like "this has to happen", I think it's be pretty scary world for some of the public as this smashes up against..
... "longCOVID" fears & "persistent infection" research outputs. I'm afraid I have no words to help beyond- vaccines are our best bet and infections will happen but will be milder thanks to immunity.
Try and clear your feed of the academic scientific minutiae of this vaccine is a bit better than that or infection followed by vaccination is better than just vaccination. Wear a good mask, take precautions and most of you will be fine.
Others won't. Even if vaccinated.
Read 4 tweets

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