Thread by @ClagueNjc36

@AnilvanderZee @ZacharyGrinDPT @Silas33 @ShaneyWright @PaulGarnerWoof @PhysiosForME 1. Thanks @AnilvanderZee yes our feasibility study showed sign physiological abnormalities during everyday activities for #pwme with #pem. Using a portable metabolic system we found a high RER during many everyday activities such as doing stairs, bathroom activities and cognitive

@AnilvanderZee @ZacharyGrinDPT @Silas33 @ShaneyWright @PaulGarnerWoof @PhysiosForME 2. activities. Some people went over 1 just in supine. Some people had low O2 others high co2. A sign number had OI some with POTS some with inc BP some with decr BP. Using hrv monitors all had low hrv with over half showing no physiol recovery day or night for up to 5 days.

@AnilvanderZee @ZacharyGrinDPT @Silas33 @ShaneyWright @PaulGarnerWoof @PhysiosForME 3. Using lactic acid monitors some people had v high lactic acid, two in particular had sign high which correlated with their leg pains. The difficulty is that every person had a mixture of symptoms and physiological presentations. But all had #pem exac by exercise.

@AnilvanderZee @ZacharyGrinDPT @Silas33 @ShaneyWright @PaulGarnerWoof @PhysiosForME 4. Anyone working with #pwme and #longcovid with #pem should be doing physiological measurements to check their response to everyday activity. They should be listening to the pts if they say they have #pem and should proceed with extreme caution. 2 x 50 minute ex progs per week

@AnilvanderZee @ZacharyGrinDPT @Silas33 @ShaneyWright @PaulGarnerWoof @PhysiosForME 5. as suggested by this study would cause sign harm for people we have seen with #ME and #longcovid with #pem. @PhysiosForME @LongCOVIDPhysio @MichelleBull4 @Hilliard_Nat @karenphysiocouk @DoctorsWithME @LongCovidAdvoc @long_covid @LongCovidSOS @LongCovidKids