#triggerwarning#RoeVWade
This is a very long 🧵from a MD colleague who wanted to share her whole story regarding what is at stake with the likely SCOTUS decision -I will use her words in this thread.
This is a story of what is at stake. Read all of it.
1/n
2/n
If you're on the fence about being an ally for those fighting for the span of women's reproductive options that American women deserve, here's her story
3/n In fellowship she got pregnant on Nuvaring. She wasn't upset and fully intended to stay pregnant. Wk 9, u/s showed a thickened nuchal fold and incr fluid (warrants a further workup for possible genetic problems). F/u bloodwork was not reassuring.
4/n She had a CVS (chorionic villus sampling) done at 11 wks to see if there was a genetic problem. Her cervix was dilated and a device placed in the uterus to sample the placenta. It is painful
5/n It took almost 2 wks for the results to come back as Down's syndrome with hydrops (large amounts of fluid building up in baby's tissues/organs). Downs along w/ hydrops is a grave diagnosis w/ low probability of live fetus at term and even lower chance of survival beyond birth
6/n F/u u/s showed worsening hydrops, essentially heart failure. Her heart was broken and she was in her 2nd trimester trying not to show emotion at work or wear anything but scrubs bc nobody knew
7/n She had a high risk MFM (maternal fetal medicine) doctor that she trusted and if it had been as it should, she would have scheduled a D&E (dilation& extraction) since the fetus was not going to survive and going to term risked her health as well.
8/n
but even 10 yrs ago when this happened her MFM had to go to a committee to fight for the procedure to have a D&E for a dying fetus. Fight w/ a panel of individuals, more than 1/2 of whom were not medical providers. 1 was clergy. After another 10 days approval was given.
9/n She was now 15 weeks 3 days. In order to prep for a procedure at this gestational age, she had to take misoprostol (one of 2 common medical abortion pills)the night before to soften the cervix & decrease chance of issues during surgery.
10/n
She never had a harder time taking pills in her life. She stared at them for hours bc she didn't want to admit this reality. But she did take them.
11/n.
The next morning as she was getting ready to go to the hospital she began to have severe pain & nausea. She delivered the fetus in the shower (keep in mind she is a MD/trained OB/GYN). She was bleeding a lot & called her friend from fellowship and had him call her MFM doc
12/n She sat on the floor of her apt w/ a dead almost 16 wk fetus in a pool of blood hoping the placenta would detach & she would stop bleeding. She took the last misoprostol to move this along.
13/n Finally the placenta let go &everything calmed down in time to tell people she didnt need an ambulance.
14/n If Roe is dismantled, she would have been forced to carry the fetus to term explaining to everywhere who said congrats that the baby was not compatible with life but thanks anyway. Or her MD would have to risk his license & livelihood to help her terminate anyway.
15/n Her dead fetus was lovingly wrapped and buried at yellow springs on a remote trail.
16/n She allowed us to share this story bc there are too many people that want to conveniently lump anyone seeking assistance as "baby killers" etc but that is not true. And honestly, she didn't have to write any of this. Because decisions w/ her doctor ARE NOBODY ELSE'S BUSINESS
17/n She ends by saying that she hopes that this story gains some allies in the coming months to stop this insanity. The time is now to get off the couch and do something.
Fin
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Moderna initiating eua for under 6 will potentially be part of a larger eua app related to their under 18 cohort which has not yet had action (likely due to concerns about safety signals in 12-17) - so what does this mean potentially ?
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Means that moderna has more data than their interim analysis announced March 23 but still not sure if they have 2 month follow up on half the patients yet /2 investors.modernatx.com/news/news-deta…
So the initiation means that the process of submitting full data could take 1-2 weeks and then fda needs to read through hundreds if not thousands of pages to prepare its assessment for vrbpac /3
1/n New CDC Guidance-what it does and doesn't say:
1.Greater emphasis on hospital capacity (for those asking its BOTH hospitalizations for and with covid which is only a thing for people who dont see patients)
2.Allows for higher cases/100k=shifting to phase w/less disease burden
2/n 70% of country is in medium-low transmission= no universal indoor masking recommended including schools (note that color scheme has changed from blue/yelllow/red to green/yellow/orange) - I liked the red-its a universal sign to stop and take it seriously.
3/n CDC recommends that in the medium covid-19 community level you talk to a health care provider re wearing a mask if you are @ increased risk of dz from covid-19. allow me to answer the question here and now. yes, just wear a mask.
Long 🧵on kids vaccine for under 5-understanding how we got here, where we are going and what we need to know.
2/Lets go back to 12/17/21 Pfizer press release:
Compared to the 16- to 25-year-old population in which high efficacy was demonstrated, non-inferiority was met for the 6- to 24-month-old population but not for the 2- to under 5-year-old population in this analysis.
3/ No safety concerns were identified and the 3 µg dose demonstrated a favorable safety profile in children 6 months to under 5 years of age
Japan has an incredibly robust set of requirements around "abnormal deaths" including examining suicide notes/emails, interviews with family members and reviewing documents. They identify major categories (family/health/economy/work/school etc) which also gives us great detail.
Analysis has some serious limitations including exclusion of 30% of deaths/takeaway for the US:
1.we could use similar detail/standardized methods for reporting death by suicide 2. as @miller7 points out we have seen this coming-cont-
The level of suicidal ideation/grief/exquisite pain we are seeing in primary care/peds is staggering. Not a day goes by where patients of all ages/race/identity do not break down in tears but we cram them into 10-15 minute aliquots and hope for the best.
Omicron BA.2 -what we know and some possible scenarios. This is also referred to as the "stealth variant" which has only added to the confusion since the variant IS detected by PCR and Rapid Ag and not as stealth as the name implies.
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2/Omicron not one variant but a family of 3 variants- BA.1/BA.2/BA.3
BA.1 is responsible for almost all cases in the US (the OG variant)
BA.2 has been detected as early as Nov 2021 and is responsible for 45% of infections in Denmark + increasing number of UK infections
3/ It has been detected in the US and will likely become responsible for a growing # of Omicron infections here; it is more infectious and VERY EARLY UK data points to ease of transmissibility especially among household members (higher secondary attack rate compared to BA.1)
Nursing Homes and Covid-19- the state affairs- thank you @JonLemire for taking time to discuss this topic @MSNBC@WayTooEarly a long 🧵 that I start with a picture from a NH in rural Michigan: yep, thats right- 14 staff out with covid-19 infections.
2/ A series of Graphs with situation today: data from @CDCgov illustrating cases by vaccine status-
clear decoupling among those w/ boosters vs not boosted
cases of vax but not boosted quite close to unvax-this is unadj data but reflective of highest efficacy of 3rd dose in NH
3/Next up-cases-data lag by about a week, but state data which maps to experience in many states-note Michigan data below followed by national trend-note low case counts this past year=vaccine.vaccine.vaccine