THREAD on current Covid situation in the UK:

TLDR: rapidly coming down from recent Omicron BA.2 peak but consequences of high infections are becoming clear.

Covering vax, infections, hospitals, deaths, long covid, variants...

1/14
On vaccination: we've made good progress in giving eligible adults their 4th dose but less well on boosting immuno-compromised adults.

But vax of 5-11 yrs is basically not happening. Many will be ineligible due to recent covid infection, not enough to explain low numbers 2/14
Good news on current wave though - ONS infection survey shows steep drops now in number of people infected and across all ages - particularly kids, helped by recent holidays.

Hospitalisations are falling rapidly too in all nations and across all ages. 3/14
% of hosp patients there primarily cos of Covid has stabilised at ~40% from ~75% with Delta.

Likely cos of high infectiousness (-> incidental adms), high pop immunity (esp after xmas boosters) & Omicron bit milder than delta.

(even incidental need infection control tho)
4/14
Deaths within 28 days of a positive test by date of death are declining now in all nations.

Deaths with covid on the causal pathway (death certificates) are more lagged and still going up in E&W week to 22 Apr (but affected by easter). Likely will decline from now. 5/14
From ONS death certificates, 16,000 people have died so far in the Omicron wave.

While this is far lower than the pre-vax Alpha wave in Jan 2021, it's almost the same as died during Delta wave - despite vaccination & in shorter time period.

High nums of infections matter 6/14
The latest ONS Long Covid report came out. It confirms that the number of people living with long covid continues to rise - now 1.8m people (2.8% of the whole population!).

Most people report some or a lot of impact on their daily lives. 7/14
*235,000 people* have been living with long covid since the very start - over 2 years

The smaller 25K in the middle? That's from the 3 mnths last spring with v few infections (see 3/14). The almost 400K this year? All Omicron.

Infections matter. Never pretend they don't. 8/14
For the first time, ONS have also published proportion of triple vaxxed people who then report long covid (and by variant).

The headline news is it's about 8%-9% of people - even after boosters. About 5%-6% say it's impacting their life. That's high. 9/14
This is all for 1st infections only - we don't know yet what it looks like on second or third infection.

But if it's even vaguely similar then it's just not sustainable to have this rate of long covid - which is highest in working age adults - and key worker professions. 10/14
On variants - currently BA.2 is dominant in the UK - our 5th dominant variant.

Omicron subvariants BA.4, BA.5 are behind a new wave of infections in S Africa and BA.2.12.1 in the US. 11/14
They all have advantage over BA.2 - don't seem more severe but likely to cause a new wave - perhaps small, perhaps large (depends on how our prev omicron immunity holds up + boosters + summer).

But all 3 currently growing here but still v early days. 12/14
Judging by BA.2 growth against BA.1, prob at least 4-6 weeks before we see any impact on overall cases. We'll see. Also depends on if they take off in schools (v few PCR tests in kids now!).
If I had to bet, I'd bet smaller wave than last 2 but still disruptive.
13/14
So - this wave is on its way out which is good. But regardless of the narrative of "it's mild" and "we're living with it", we've had 1000's of deaths and 100,000s people developing long covid.

The next wave might also be sooner than we'd like. 14/14

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More from @chrischirp

Oct 19, 2024
Important 🧵on our new peer-reviewed paper:

The pandemic is as bad as it ever was for babies - in year to Aug 2023, 6,300 babies under 1 were admitted to hospital wholly or partly BECAUSE of Covid.

They are ONLY age group where admissions have NOT gone down over time 1/17 Image
Our study, led by Prof @katebrown220, looked at all hospitalisations in England in children with a Covid diagnosis or positive test from Aug 2020-Aug 2023.
We then *excluded* all admissions where a Covid diagnosis was incidental (ie not why they were in hospital)
2/17 Image
Infants (babies under 1) are generally at higher risk from respiratory infections, plus they are the age group that, if infected, are overwhelmingly meeting the virus for the first time.

They are not vaccinated and have not had it before. 3/17
Read 18 tweets
Sep 26, 2024
Prof @Kevin_Fong giving the most devastating and moving testimony to the Covid Inquiry of visiting hospital intensive care units at the height of the second wave in late Dec 2020.

The unimaginable scale of death, the trauma, the loss of hope.
Please watch this 2min clip.
And here he breaks down while explaining the absolute trauma experienced by smaller hospitals in particular - the "healthier" ICU patients were transferred out, leaving them coping with so much death.

They felt so alone.
Here Prof Fong explains how every nurse he met was traumatised by watching patients die, being only able to hold up ipads to their relatives and how it went against their normal practice of trying to ensure a dignified death, with family there.
Read 5 tweets
Aug 28, 2024
THREAD: I asked what the point of Public Inquiries is for @bmj_latest

We've spent hundreds of millions of £ on Inquiries over last decades, generating deep understanding of failures & 1000s of recommendations.

But v few recommendations get implemented!
What is going on?

1/12 Image
E.g. Covid-19 Inquiry has cost £94 million so far - and is projected to cost over £200m by its end (it still has years to go).

1st report published (out of at least 9) found major flaws and proposed 10 recommendations.

Chances are low that they will be implemented :-( 2/12


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Inst for Government looked at 68 Inquiries from 1990-2017.
The Inquiries cost over £630 million and made 2,625 recommendations.

Only 6/68 Inquiries have received full scrutiny by a parliamentary select committee on implementation of recommendations. 3/12 Image
Read 12 tweets
Aug 9, 2024
🧵War causes direct civilian deaths but also indirect deaths over the following years.

Recent paper estimates eventual total direct & indirect deaths in Gaza attributable to the war - 10% of entire pop'n.

I want to explain these estimates and why deaths must be counted. 1/13 Image
Why count casualties from war anyway? For moral, legal and strategic reasons.

1 - owe it to those who have died
2 - International law says must count & identify dead as far as possible
3 - monitor progress of war & learn from tactics

2/13 Image
There are direct and indirect casualties of war. Direct deaths include those who killed by fighting or bombs.

Indirect deaths are those that die when they would otherwise have lived because of one or more of: lack of food, healthcare, housing, sanitation, income, hope. 3/13 Image
Read 14 tweets
Aug 1, 2024
THREAD: the summer Covid wave in the UK continues.
Basically, there is a LOT of Covid around and not a lot of other respiratory viruses.

If you have cold or flu symptoms, it's probably Covid.

The latest hospital data from England shows steady, quite high levels. 1/8 Image
But admissions don't tell us how much virus is circulating more generally. The best (but imperfect) measure we have is wasterwater measurements, and only in Scotland and not England.

Scotland's wastewater is showing a huge July peak - highest since Omicron's 1st yr in 2022 2/8 Image
Because different people shed different amounts of virus and variants can matter too, you can't for sure infer how many people were infected between different wasterwater peaks. BUT given the size, I'd say it's pretty likely this is the largest peak since 2022 in Scotland 3/8
Read 8 tweets
Jul 23, 2024
THREAD:
I wrote about Baroness Hallett's Inquiry Module 1 report for @bmj_latest .

She found that there was *never* a plan to keep a pandemic death toll down - I discuss this and what it means going foward.

Main points below: 1/14 Image
The headline most seen is that the UK planned for the wrong pandemic.

While it is true that was far too narrow a focus on a flu pandemic, that is not the most telling bit.

To me the most telling bit, is what the plan did NOT do 2/14


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The issue is less the wrong disease, but that there was never a plan to prevent one at all – of any disease type.

The plan was *never* about reducing the number of pandemic deaths. 3/14 Image
Read 14 tweets

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