Saretta Lee & Katerina Theocharous up next to present a literature review about clozapine and chemotherapy #RANZCP2022 
Research questions to determine how continuation or cessation of clozapine during chemotherapy impact patients risk of haematological adverse and psychiatric adverse outcomes #RANZCP2022
It is feasible & often desirable to continue clozapine through chemotherapy, due to high risk of mental state deterioration from cessation. But, continuation requires a multi-disciplinary approach - Saretta Lee #RANZCP2022
If neutropenia occurs, it is unclear whether clozapine should be temporarily ceased, but it appears that rechallenge is usually tolerated - Saretta Lee #RANZCP2022
Last presentation in this session is Prof Kay Whilhelm @StVHealthAust talking about the 4Ds: mental health in heart and lung transplant recipients #RANZCP2022
4Ds = depression, delirium, decline in cognitive function & disordered attachment behaviour - Prof Wilhelm #RANZCP2022
Many patients now being accepted for transplant with mental health conditions that would not have been accepted in earlier years of transplant - Prof Wilhelm #RANZCP2022
Common predictors of delirium = intraoperative hypotension, previous smoking history, previous alcohol abuse & ICU benzodiazepine use - Prof Wilhelm #RANZCP2022
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