Next we have Dr. Ramona Hopkins with “Should Prognostication in the ICU Be Based on Age, Disability, and Frailty?” #ATS2022
Making predictions is hard. This meta-analysis showed a huge range of mortality and substantial heterogeneity in outcome. #ATS2022
A systematic review of frailty found that it was associated with higher mortality, but there was a lot of heterogeneity in patients and their outcomes. #ATS2022
Looking at longer outcomes post-COVID-19 there are a wide range of outcomes. #ATS2022
A lot of these symptoms persist over time. #ATS2022
This paper tried to identify factors within COVID patients and compared them to patients with sepsis. #ATS2022
So do the interventions that we use in younger adults also work in order adults? There are very few trials looking at this. #ATS2022
There is a difference between having a different baseline risk versus subgroup effect modification. In the first the intervention works the same in the groups (there is just differing risks), and in the 2nd the intervention works differently between the groups. #ATS2022
This systematic review looked at subgroup effects. #ATS2022
There are different criteria to judge whether subgroup effects are trustworthy or not. #ATS2022
What did they find? Only 4 trials found an effect modification by age. #ATS2022
HYBERNATUS looked at vented patients in status epilepticus with an intervention of hypothermia. #ATS2022
TRICS looked at transfusion goals in CV surgery patients. Older patients did better with the restrictive strategy (liberal was better for younger patients). #ATS2022
SPICE III looked at vented patients and evaluated Precedex as the primary sedative. Older patients seemed to do better with Precedex. #ATS2022
COACT looks at OHCA without ST elevation with an intervention of immediate vs delayed angiography. Older patients seemed to do better with early angiography. #ATS2022
So do interventions work in older adults? Yes! Don’t use their age as a rationale for withholding interventions if they otherwise would want the intervention. #ATS2022
My last session for #ATS2022 day 3 is “Priorities from a Joint-Society ATS Policy Statement on Palliative Care in Serious Respiratory Illness”!
First we have Dr. Donald Sullivan with “Fundamental Principles of Palliative Care in Respiratory Disease and Highlights from the Policy Statement.” #ATS2022
Unfortunately, “going with your gut” does not perform well in predicting mortality. However, this is associated with more goals of care conversations. #ATS2022
What we really need to takeaway is that we need to shift palliative care conversations and interventions to earlier in the disease. #ATS2022
If any of these levels change and cross the threshold it should trigger a conversation. #ATS2022
First up for tweetucation today at #ATS2022 is “Communicating Prognosis to Critically Ill Patients and Their Families: Challenges and Recommended Strategies Which Consider Culture and Preferences.” Im super pumped for this one! #CommunicationMatters #MedEd
First up is @UABPulmonary’s very own @anandiyermd (who I ADORE) with “Prognosticating in Serious Respiratory Illness: Assessing Risk Amidst the Unknown”! #ATS2022