📌NEJM. REVIEW. Autor: Dr. E. BRAUNWALD
GLIFOZINAS EN EL MANEJO DE ENFERMEDAD CV

⚠️SGLT2i⚠️ Cambio de Paradigma
⬇️ Eventos CV💔 y Hospitalizaciones🏥 por IC, independiente DBT2, en amplia gama de FEYs
⬇️ Progresión de falla renal

nejm.org/doi/pdf/10.105…
#CardioTwitter
🚩≈57k ptes. ⬇️Eventos CV en 6 trials mas relevantes en ptes con DBT2.
-📉RRR Eventos CV mayores 11%
-📉RRR Muerte CV 14%
-📉RRR Hospitalización por IC 32%
🚩 Renoprotección. Meta-análisis ≈38k ptes.
⬇️Eventos renales en 4 trials mas relevantes en ptes c/ DBT2.
-📉RRR 33 %👉progresión a diálisis, trasplante o muerte renal
- 💡Beneficios en todo el rango de función renal, diabético o no e independiente del control glucémico

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