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Jun 16 โ€ข 4 tweets โ€ข 4 min read
Another exciting milestone ๐Ÿ”ฅ. Our #SingleR paper just crossed the 1K citation threshold!
@MallarBhattach1 @atulbutte @NatImmunol
nature.com/articles/s4159โ€ฆ

>> Image
In this paper, we introduced #SingleR, an R package for annotating cells in scRNA-seq data, and used it to identify a novel transitional profibrotic macrophage state. bioconductor.org/packages/releaโ€ฆ Image
This couldn't have happened without the help of Aaron Lun who took it upon himself to rewrite the package for @Bioconductor, continues to maintain it, and wrote this awesome SingleR book. bioconductor.org/books/release/โ€ฆ Image
Oh, one last thing - we pronounce it singler, like @Tinder, not single R. It was supposed to be "singler, matching app for single cells" ๐Ÿ˜‰

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Jun 18
ืงืจืืชื™ ืืช ื“ื™ื•ื ื™ ื”ื•ืขื“ื” ื•ืืช ื”ื ืชื•ื ื™ื ืฉื”ืฆื™ื’ื• ืžื•ื“ืจื ื” ื•ืคื™ื™ื–ืจ, ื•ืฆืจื™ืš ืœื”ื•ื“ื•ืช ืฉืžืชื ื’ื“ื™ ื”ื—ื™ืกื•ื ื™ื ืฆื•ื“ืงื™ื ื”ืคืขื ื‘ื‘ื™ืงื•ืจืช ืฉืœื”ื. ื”ื ื›ืžื•ื‘ืŸ ืื™ื‘ื“ื• ืื•ืชื ื• ื‘ื–ืขืงื•ืช ื”ื–ืื‘ ื–ืื‘ ืฉืœื”ื ืœืื•ืจืš ื›ืœ ื”ื“ืจืš, ื•ื‘ืจื•ืจ ืฉื›ืœืœ ืœื ืžืขื ื™ื™ืŸ ืื•ืชื ื”ื ืชื•ื ื™ื ื”ืืžื™ืชื™ื™ื, ืื‘ืœ ื”ืคืขื ื™ืฉ ืืžืช ื‘ื›ืš ืฉื”ื ื™ืกื•ื™ื™ื ื”ืงืœื™ื ื™ื™ื ืœื ืžืจืฉื™ืžื™ื ื‘ืœืฉื•ืŸ ื”ืžืขื˜ื”. >>
ื”ื ื™ืกื•ื™ ื”ืงืœื™ื ื™ ืฉืœ ืคื™ื™ื–ืจ ื›ืฉืœ. ืจืืฉื™ืช ื ื™ืชืŸ ืœืจืื•ืช ืืช ื”ื ื•ื’ื“ื ื™ื ื”ืžื ื˜ืจืœื™ื: ืœื ื”ื™ืชื” ืชื’ื•ื‘ื” ืื—ืจื™ ืฉืชื™ ืžื ื•ืช ืžื•ืœ ืื•ืžื™ืงืจื•ืŸ. ื›ื“ื™ ืœื”ืฆื™ืœ ืืช ื”ื ื™ืกื•ื™ ื”ื ื”ื•ืกื™ืคื• ืžื ื” ืฉืœื™ืฉื™ืช (ืฉืœื ื”ื™ืชื” ื‘ืชื•ื›ื ื™ืช ื”ืžืงื•ืจื™ืช) ื•ืฉื ื›ืŸ ืจืื• ืชื’ื•ื‘ื” ืžื•ืœ ืื•ืžื™ืงืจื•ืŸ. Image
ืื‘ืœ ืžืกืคืจ ื”ื™ืœื“ื™ื ืฉืงื™ื‘ืœื ื• ืžื ื” ืฉืœื™ืฉื™ืช, ื•ื–ืžืŸ ื”ืžืขืงื‘ ืื—ืจื™ื”ื ื”ื™ื” ืงืฆืจ ื•ืœื›ืŸ ื”ืžืกืคืจ ืฉืœ 80% ื”ื’ื ื” ืžื‘ื•ืกืก ืขืœ ื‘ืกืš ื”ื›ืœ 10 ื™ืœื“ื™ื ืฉื ื“ื‘ืงื• ืžืฉืชื™ ื”ืงื‘ื•ืฆื•ืช ื•ื‘ืขืœ ืกื˜ื™ื™ืช ืชืงืŸ ืฉืœ 14%-97%. ื–ื• ืชื•ืฆืื” ืฉืœื™ืœื™ืช. Image
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Apr 29
ืขื‘ืจืชื™ ื‘ืงืฆืจื” ืขืœ ื”ืžืืžืจ. ื‘ืกืš ื”ื›ืœ ืžืืžืจ ืžืขื ื™ื™ืŸ, ื•ืื ื™ ื—ื•ืฉื‘ ืฉืฉื™ืžื•ืฉ ื‘ืงืจื™ืื•ืช ืœืžื“ืดื ื–ื• ื‘ื”ื—ืœื˜ ืชื•ืกืคืช ืจืื•ื™ื”.
ื›ื‘ืจ ื“ื™ื‘ืจื ื• ื‘ืขื‘ืจ ืขืœ ื›ืœ ื”ื—ื•ืœืฉื•ืช ืฉืœ ืžืืžืจ ืžื”ืกื•ื’ ื”ื–ื” - ื ืชื•ื ื™ื ืื’ืจื˜ื™ื‘ื™ื™ื ื•ืื™ืŸ ืžื™ื“ืข ืื™ืฉื™ ืขืœ ื—ื™ืกื•ื ื™ื, ืกื™ื•ื•ื’ ืงืจื™ืื•ืช ืฉืœ ืžื“ืดื, ื•ืขื•ื“ ื•ืขื•ื“. ืื‘ืœ ืขื›ืฉื™ื• ื›ืฉื™ืฉ ื ืชื•ื ื™ื ืืคืฉืจ ื’ื ืœื”ืชื™ื™ื—ืก ืœื ืชื•ื ื™ื >>
ื‘ืขื™ื ื™ ื”ืžื•ื“ืœื™ื ื”ืกื˜ื˜ื™ืกื˜ื™ื™ื ืขืœ 5 ื”ื—ื•ื“ืฉื™ื ืฉืœ 2019 ืœ-2021 ืื• ืขืœ ืฉื ื” ืฉืœืžื” ื”ื ื—ืœืฉื™ื ืžืื•ื“ ื•ืœื ืžืขื ื™ื™ื ื™ื. ืงืœ ืœืจืื•ืช ืž-figure 1 ืฉืžืกืคืจ ื”ืงืจื™ืื•ืช ืœื ืชืœื•ื™ ื‘ื–ืžืŸ ืฉืœ ื”ืฉื ื” (ื‘-2019 ื”ื™ื• ืžืขื˜ ื‘ื™ื ื•ืืจ-ืžืื™ ื•ื”ืจื‘ื” ื‘ื™ื•ืœื™-ื“ืฆืžื‘ืจ). ื–ืืช ืœื ื”ืฉื•ื•ืื” ืžืขื ื™ื™ื ืช. ื”ืกืชื›ืœื•ืช ืจืฆื™ืคื” ื›ืŸ ืžืขื ื™ื™ื ืช ื•ืจื•ืื™ื ืืช ื”ืฉื™ื ื‘ืคื‘ืจื•ืืจ 2021.
ื”ืฉื™ื ืฉืœ ืžืกืคืจ ื”ืงืจื™ืื•ืช ืœื“ื•ื ืœื‘ (ืื“ื•ื) ื‘ืชืงื•ืคื” ื”ื–ื• ืงื•ืจื” ื‘ื“ื™ื•ืง ื‘ื–ืžืŸ ืžื‘ืฆืข ื”ื—ื™ืกื•ื ื™ื. ื‘ื–ื•ื ืขืœ ืชืงื•ืคืช ื”ื—ื™ืกื•ื ื™ื (ืกื’ื•ืœ ืžื ื” 1, ื›ื—ื•ืœ ืžื ื” 2) ืจื•ืื™ื ืฉื”ืคื™ืง ื”ืื“ื•ื ืžื’ื™ืข ื‘ื“ื™ื•ืง ืขื ื”ืคื™ืง ืฉืœ ืžื ื” 2 ื•ื–ื” ืžืชืื™ื ืœืžื—ืงืจื™ื ืฉืœ ืžืฉื”ืดื‘ ืฉืจื•ื‘ ืžืงืจื™ ื”ืžื™ื•ืงืจื“ื™ื˜ื™ืก ื”ื’ื™ืขื• ื›ืฉื‘ื•ืขื™ื™ื ืื—ืจื™ ืžื ื” 2. ืื‘ืœ ื’ื ืจื•ืื™ื ืคื™ืง ื‘ืžืื™, ืžื” ืงืจื”?
Read 8 tweets
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Apr 5
Getting ready to #DMCI after dark from the top of Tel-Aviv. Iโ€™ll try to live tweet the talks. Image
View from the venue. Image
Udi Goori, Anthem Israel general manager, opening #DMCI. Why are we here? To connect academia and industry to solve the pressing healthcare problems.
Read 15 tweets
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Mar 13
@NadavSharon3 kicking off the faculty of biology @TechnionLive 50th annual retreat!
@LabPMelamed on transcription regulation of hormones expression
And now meโ€ฆ thanks @AArgoetti for the photo.
Read 5 tweets
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Feb 14
ื ืจืื” ืœื™ ืฉื—ืœืง ืžื”ืฉืจืฉื•ืจ ืคื” ืžืชื™ื™ื—ืก ืœื‘ื™ืงื•ืจืช ืฉืœื™, ืื– ืื’ื™ื‘ ื‘ืงืฆืจื”, ื•ืืฉืžื— ืœื“ื™ื•ืŸ ืขื ื™ื™ื ื™ ื•ืžื›ื‘ื“.
ืื ื™ ืจื•ืฆื” ืœื”ื“ื’ื™ืฉ ืคื” ืืช ื”ืฆื“ ื”ืขื ื™ื™ื ื™ ืฉืœ ื”ืžื—ืœื•ืงืช ื•ืžื” ืืคืฉืจ ืœืœืžื•ื“ ืžื›ืš ืœื’ืœื™ื ื”ื‘ืื™ื. ื”ืžื—ืœื•ืงืช ื‘ื™ื ื™ื ื• ื ืกื•ื‘ื” ืกื‘ื™ื‘ ืฉืœื•ืฉ ืืžื™ืจื•ืช ืฉืœื”ื‘ื ืชื™ ื ื˜ืขื ื•:
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1. ื”ื’ืœ ื™ื”ื™ื” ืงืฆืจ, ืฆืคื•ื™ ืœื”ืกืชื™ื™ื ืขื“ ืกื•ืฃ ื™ื ื•ืืจ
2. ืœื ื ื—ืฆื” ืืช ืกืฃ ื”ืกืคื™ืงื” ื‘ื‘ืชื™ ื—ื•ืœื™ื
3. ืื™ืŸ ืื™ืš ืœื”ืื˜ ืืช ืื•ืžื™ืงืจื•ืŸ ืœืœื ืกื’ืจ ืžืœื

ื‘ืžื‘ื˜ ืœืื—ื•ืจ ื ื™ืชืŸ ืœื‘ื—ื•ืŸ ืืช ื”ื˜ืขื ื•ืช:
ืœื’ื‘ื™ 1, ืืžืฆืข ืคื‘ืจื•ืืจ ื•ื”ื’ืœ ืขื•ื“ ืคื”. ืขื“ื™ื™ืŸ ื™ืฉ ืขืฉืจื•ืช ืืœืคื™ ื”ื“ื‘ืงื•ืช ื‘ื™ื•ื. ืขื“ื™ื™ืŸ ื™ืฉ ื™ื•ืชืจ ืž-1000 ืžืื•ืฉืคื–ื™ื ืงืฉื” ื‘ื‘ืชื™ ื”ื—ื•ืœื™ื. ื”ื’ืœ ื”ื–ื” ืืจื•ืš ื•ืงืฉื”.
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Jan 27
ื‘ืฉืขื” ื˜ื•ื‘ื” ื ืจืื” ืฉืขื‘ืจื ื• ืืช ืฉื™ื ื”ื’ืœ ื‘ืžืื•ืžืชื™ื. ืืคืฉืจ ืœืจืื•ืช ื–ืืช ื‘ืžืกืคืจ ื”ืžื‘ื•ื’ืจื™ื 60+ ืฉืื•ืžืชื• ื”ื™ื•ื, ื•ืœืจืืฉื•ื ื” ื™ืฉ ื™ืจื™ื“ื” ืœืขื•ืžืช ื”ืฉื‘ื•ืข ื”ืงื•ื“ื. ืืžื ื ื™ืจื™ื“ื” ืงืœื” ืฉืœ ืจืง 6%, ืฉื—ืœืงื” ืื•ืœื™ ืžื•ืกื‘ืจืช ืžื™ืขื™ืœื•ืช ื”ื‘ื•ืกื˜ืจื™ื, ื•ืขื“ื™ื™ืŸ, ื ืจืื” ืฉื”ืฉื™ื ื›ื‘ืจ ืžืื•ื—ืจื™ื ื•.
>>
ืื‘ืœ ืฆืจื™ืš ืœื”ืกื‘ื™ืจ ืžืฉื”ื• - ื‘ื’ืœ, ื”ืฉื™ื ืชืžื™ื“ ืžื’ื™ืข ื‘ืื•ืชื• ื”ื–ืžืŸ. ื›ืœ ื”ืžื•ื“ืœื™ื (ืกื’ืœ, ื’ื–ื™ืช ื•ื“ื”-ืœื™ืื•ืŸ) ื—ื–ื• ืืช ื”ืฉื™ื ื”ืฉื‘ื•ืข. ืขืœ ื–ื” ืงืฉื” ืžืื•ื“ ืœื”ืฉืคื™ืข. ืขืœ ืžื” ืืคืฉืจ ืœื”ืฉืคื™ืข? ืขืœ ื”ืฉื™ื ืฉืœื•. ื‘ืžื—ื“ืœ ืฉืœื ื• ืงื‘ืขื ื• ืืช ืฉื™ื ื”ื’ืœ ื›ืš ืฉื™ื”ื™ื” ื’ื‘ื•ื” ื™ื•ืชืจ ืžื›ืœ ืžื“ื™ื ื” ืื—ืจืช.
ื•ืขื›ืฉื™ื• ื ืืœืฅ ืœืฉืœื ืืช ืžื—ื™ืจ ื”ืžื—ื“ืœ:
1. ื›ื›ืœ ืฉื”ืฉื™ื ื’ื‘ื•ื” ื™ื•ืชืจ, ื›ืš ื”ื™ืจื™ื“ื” ืœื•ืงื—ืช ื™ื•ืชืจ ื–ืžืŸ ื•ื™ื•ืชืจ ืื ืฉื™ื ื ื“ื‘ืงื™ื ื‘ื™ืจื™ื“ื”.
2. ื”ืื™-ืกืคื™ืงื” ืฉื‘ื” ื ืžืฆืื™ื ื‘ืชื™ ื”ื—ื•ืœื™ื ื™ืžืฉื™ืš ืขื•ื“ ื–ืžืŸ.
3. ื›ื™ืชื•ืช ื”ืœื™ืžื•ื“ ื™ืžืฉื™ื›ื• ืœื”ื™ื•ืช ืจื™ืงื•ืช.
4. ื”ืชื ื•ืขื” ืชืžืฉื™ืš ืœื”ื™ื•ืช ื›ืžื• ื‘ืจืืฉ ื”ืฉื ื”.
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