Fallacy Alarm Profile picture
Jun 27 11 tweets 4 min read
1/X Why $AMRS owns the #Synbio👑and $DNA needs a telescope to see them.

$DNA is valued at 3x $AMRS while both have comparable revenue levels and 75% of $DNA's revs relate to Covid testing which is not relevant for the long term story.
2/X Key difference is that $AMRS takes control of entire value chain from R&D to manufacturing to end product marketing (vertical approach), while $DNA focuses on R&D, i.e. designing metabolic pathway & letting partners/customers do the rest (horizontal).
3/X For $AMRS, the molecule is the product, for $DNA it is the (yeast) strain.

$DNA's horizontal approach is supposed to be a strength vs. $AMRS by freeing resources for what supposedly matters most. Reasoning that is deeply flawed. It assumes that $DNA is/will be better in R&D.
4/X But everything that Ginkgo claims to do, Amyris also claims to be doing. There is no way anyone (incl. the @ARKInvest gang) can truly assess the both tech platform outside-in from the bottom up. They have tried here: medium.com/ark-genomics-r…
5/X Which I have commented on in the article below.

We have to make inferences indirectly. Look at where their end products stand commercially. Look at the BS vibes radiated by Jason Kelly when he compares $DNA to $AMZN.
fallacyalarm.substack.com/p/why-is-there…
6/X Look at how application focused $AMRS has been all its existence. #Synbio will likely revolutionize product design, supply chains and industrial manufacturing in many areas. But for now it is still in the proof of concept stage.
7/X It must prove it is scalable, cheaper and better than traditional tech. That is why $AMRS takes entire value creation chain in their hands with all its painful capital needs & risks, while $DNA takes easy route.

Capital light is fine until you run out of other ppl's money.
8/X I won't go into detail on $DNA's shady 3rd party equity entanglements, but in terms of the beauty of the equity participation/royalty streams: This is exactly what $AMRS is doing as well in licensing deals like with DSM which I have commented on here: fallacyalarm.substack.com/p/deconstructi…
9/X Even better, $AMRS works with established brands more experienced with product market fit than start-ups partnering with $DNA.

Preferring the horizontal approach assumes hardest part is coming up with the suitable strains and mass production of the molecules is the easy part
10/X This goes against historical evidence in multiple industries, especially in complex manufacturing. The most successful companies share their skills in having the best execution, not in having the best ideas ( $TSLA, $AMZN, $META, $AAPL). Scale best, dominate the rest.
11/11 My deep dive on $AMRS can be found in the article below. Please consider subscribing or retweeting if you like what you read, it helps a lot building reach.
fallacyalarm.substack.com/p/amyris-inves…

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More from @fallacyalarm

Jun 28
1/X Baburu Keiki - Is this the Nikkei 1990 moment for the S&P?🧵

On Dec 29, '89, the #Nikkei hit an ATH of 38,957. It was the peak of the biggest boom Japan had ever seen. Sony, Toyota & co took over the 🌎

Or so it seemed. That ATH was never seen again to this day, 33y later. Image
2/X By mid '92 it was down 50%. And in fall '12, on the eve of the start of Abenomics it was down 77% from its ATH. After 23y had passed.

Whenever there is a correction in the S&P, I think about Japan and what lessons it can teach us. Come join me for a trip far east.
3/X I tend to compare money supply growth with index appreciation to learn about the overall ambitiousness in the valuation.

While the S&P tends to follow USD money supply in lockstep, the Nikkei has disconnected completely from Yen supply after 1989.

fallacyalarm.substack.com/p/a-measuring-… Image
Read 12 tweets
Jun 27
1/6 i am seeing ppl referring to the affordability crisis of housing a lot lately and often they implicitly or explicitly make the inference that this is a driver for a housing price correction.

affordability is neither a necessary nor a sufficient condition for price drops.
2/6 that argument would be as trivial as stating that something has to come down just bc it has come up. this is not proper analysis. instead ask yourself why it has gotten less afforable in the first place and whether that is sustainable.
3/6 housing has outperformed other goods and services bc of demographic forces, a change in consumer preferences (seeking more privacy for home office, leisure activities and for health and political reasons) and store of value considerations due to excessive monetary debasement.
Read 6 tweets
Jun 24
1/X From generation heads-down to generation heads-up. How $META will dethrone $AAPL. 🧵

Since the digital revolution started, most value was created at the gatekeeper who connects ppl with cyberspace, the human machine interface (HMI), going regularly through paradigm shifts.
2/X It started with PCs in the 80s, when $MSFT & $INTC symbiosis captured most value of revolutionary microchip tech bringing unprecedented computing power into ppl’s homes.

Next shift was the smartphone, particularly Job's legendary iPhone intro:

3/X Revolutionized HMI forever. $AAPL was not the first. It was just time for the mobile computing revolution based on the convergence of several key techs, mostly computing power & display/touch screen tech. Winners are rarely the first, they just execute best.
Read 18 tweets
Jun 20
1/17 What is Real World AI (RWAI) Computing and why will it become an important investment theme? A 🧵.

In times like this, it is tempting to attempt making short term bets on cyclical trends, but historically the real wealth creation came from big innovation events.
2/17 Mobile Computing

$AAPL unveiled the iPhone in Jan'07. Since then the stock is up 50x. And the innovation cycle of the smartphone is still unfolding (e.g. payment terminal and the car integration). The $AAPL we know today is just a milking machine of an innovation 15y ago.
3/17 Cloud Computing

$AMZN developed AWS in early '00s. In '02, Bezos wrote his famous email mandating the use of service interfaces which laid the groundwork for their AWS ecosystem, the first features of which were publicly launched in '06. Since then the stock has done a 60x.
Read 17 tweets
Jun 17
1/5 quick 🧵 on housing prices since May data just came in

🇨🇦 housing mkt continuing going strong despite all the naysayers, up 2% MoM in May to a new record at an incredible speed. housepriceindex.ca/2022/06/may202… Image
2/5 often here that 🇨🇦 in particular is highly overvalued compared to other markets since it is up 3x since 2000. IMO this neglects the countries' geostructure. most appreciation in last two decades has been in big cities as ppl want the job opps & infrastructure. Image
3/5 therefore, the more centralized a country the more upward bias in the composite. 🇨🇦 RE is mostly Toronto & Vancouver where all immigration flows go. despite being a vast country, 🇨🇦 is highly centralized. look at Miami, SF or NY. all up 3x over same 20y ImageImageImage
Read 5 tweets
Jun 13
the longer the current energy crisis persists, the more will we see fiscal (and ultimately monetary) stimulus. in this 🧵, I'll compile instances for INCREMENTAL spending commitments beyond official budgets.

feel free to add to it.
#1

🇩🇪 reduced the gasoline tax by €0.35 as of June 1 (for now limited for 3 months). national consumption is 80m l/day, so this'll incrementally add ~€1bn to govt deficit per month, ~€10bn annually (0.3% of GDP).
#2

🇺🇦 spends $5-8bn a month to fight the 🇷🇺 invasion, which is largely financed by western deficit spending, mostly 🇺🇸 which just provided a $40bn package. if 🇺🇸 spends $60bn for this over 12 months, this is an incremental 0.3% deficit/GDP
Read 6 tweets

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