1. Now everyone can stop raising their eyebrows when I say that I exercise outdoors wearing an N95 mask. Omicron is a game-changer for transmissibility. BA.5 takes that to the next level. It's dead wrong to assume that outdoor transmission is insignificant
2. The claim that you are a thousand times more likely to contract COVID indoors than outdoors is an urban myth that remains abject nonsense, no matter how often the fairy tale has been repeated. A lie repeated often enough remains a lie
3. As SAR2 evolves towards ever more efficient airborne transmission, it has become time to relegate foolish assumptions to the effect that outdoors transmission is insignificant to the dustbin of history
4. While outdoors remains safer than in, the difference is relative and situational. Outdoor is a well-documented occurrence in the literature and is not just based on random anecdotes. Knowing that #COVIDisAirborne and wearing a mask keeps you safe thelancet.com/journals/lanep…

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More from @ToshiAkima

Jun 29
1. I am hearing more and more stories of people catching COVID on a plane while wearing an N95 mask. There are numerous reasons for this and we'll go through them to help you avoid getting COVID
2. During boarding, the air filtration system is usually not running. You know how stuffy it can get on board a plane on a hot day, when departure is delayed. Before take-off, the CO2 levels climb to eye-watering levels (it should be less than 700ppm)
3. Due to worker absenteeism, there are delays in take-off, which means longer periods with stratospheric CO2 levels. This leads to more crew getting COVID and an increase in take-off delays. It's a vicious cycle cbsnews.com/news/airlines-…
Read 14 tweets
Jun 26
I am observing a slow rise in COVID admissions (the influenza surge seems to be subsiding). Please get vaxxed to the max. Always wear a mask (N95 or better) when you leave home. If Portugal is anything to go by, we're going to be hammered by a BA.5 surge
The pattern seen in highly vaxxed Portugal is repeating itself throughout the world and not just in Australia. Ignore this warning signal at your dire peril. Do not listen to the minimisers who have gotten it wrong time and time again. Fool me twice, shame on me Image
I've heard colleagues saying they are starting to intubate COVID cases again. BA.5 has the same mutation as Delta that made it pathogenic/nasty while having the immune escape typical of the Omicron line. If you've had Omicron Mark I or II (BA.1 or BA.2), you can get BA.5
Read 7 tweets
Jun 12
Loss of smell may be a sign of dementia. A study found that people with impaired smell had over 2x the odds of developing dementia within 5 years, independent of other risk factors. The degree of olfactory loss correlated with the severity of dementia news-medical.net/health/Alzheim…
CV19 survivors had markers of damage in areas linked to the olfactory centre. It’s not clear why but one possibility is lack of input. “When we cut off input from the nose, the brain trophies. It’s one of the clearest things we know about taste and smell” nature.com/articles/d4158…
The long-term impact of COVID on neurocognitive function has yet to be fully elucidated but there is a documented neurodegenerative change even after a “mild” illness nature.com/articles/s4158…
Read 4 tweets
Jun 12
Patients with respiratory #longCOVID had 6–105 times more IFN-γ and TNF-α producing SARS-CoV-2-specific CD4+ and CD8+ T cells in peripheral blood, and elevated levels of plasma CRP and IL-6. journals.plos.org/plospathogens/…
The presence of SARS2-specific CD4+ and CD8+ cells correlated with reduced lung function (eg FEV1/FVC, DLCO) and with symptoms of breathlessness
Some will say this is damage from acute COVID. The study doesn't support this conclusion, as 60% of the pulmonary #longCOVID group had mild acute COVID. There was no difference in the frequency of SARS2-specific T cells between hospitalised and non-hospitalised #longCOVID cases
Read 4 tweets
May 29
1. A full review of the Flo Mask Pro respirator @flo_mask. Fully *independent* verdict: it's a winner. A discreet elastomeric you can wear and forget about. It “disappears”, even when worn for extended periods
2. Elastomerics fit a much higher proportion of the population on fit tests. If you don't have access to fit testing, then you have an up to 98% chance of passing in an elastomeric. But traditional elastomerics tend to be bulky or look like gas masks …ccess.s3-ap-southeast-2.amazonaws.com/AustralianAnae…
3. The @flo_mask is a more discrete alternative to elastomerics like the excellent NIOSH approved @DraegerNews X-plore 2100, being lighter, less bulky and aesthetically more acceptable. We don't call it the Peppa Pig for nothing, as it has a fine snout!
Read 35 tweets
May 29
1. A full review of the Flo Mask Pro respirator @flo_mask. Fully *independent* verdict: it's a winner. A discreet elastomeric you can wear and forget about. It “disappears”, even when worn for extended periods
2. Elastomerics fit a much higher proportion of the population on fit tests. If you don't have access to fit testing, then you have an up to 98% chance of passing in an elastomeric. But traditional elastomerics tend to be bulky or look like gas masks …ccess.s3-ap-southeast-2.amazonaws.com/AustralianAnae…
3. The @flo_mask is a more discrete alternative to elastomerics like the excellent NIOSH approved @DraegerNews X-plore 2100, being lighter, less bulky and aesthetically more acceptable. We don't call it the Peppa Pig for nothing, as it has a fine snout!
Read 24 tweets

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