Spencer Kelley Profile picture
Aug 1, 2022 β€’ 5 tweets β€’ 17 min read β€’ Read on X
@halesj126 @MondayNightIBD @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD #CDI treatment:
πŸ’ŽπŸš« oral πŸ’Š metronidazole in #IBD
πŸ’Ž@AmCollegeGastro πŸ‘‡
bit.ly/ACG-Guideline-…
πŸ’ŽIDSA : fidaxo > vanco
πŸ’ŽIBD pts might require a longer course
Non-severe:
πŸ’Š fidaxo x 10d
OR
πŸ’Š vanco x 14-21d
Severe:
πŸ’Š fidaxo x 10d
OR
πŸ’Š vanco x 21d
βž•/βž– πŸ’‰ metronidazole
@halesj126 @MondayNightIBD @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD @AmCollegeGastro #CDI treatment cont’d:
Fulminant:
πŸ’Š vanco
βž•
πŸ’‰ metronidazole
βž•
Vanco enema if ileus
Additionally:
✳️ supportive cares
✳️ πŸ”ͺ consult
✳️ πŸ€” #FMT πŸ’©πŸ”¦
@halesj126 @MondayNightIBD @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD @AmCollegeGastro As the saying goes an algorithm is worth a 1000 words and fortunately, we have the great @wabillin algo on how to approach CDI in IBD Image
@halesj126 @MondayNightIBD @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD @AmCollegeGastro @wabillin #CDI recurrence:

Risk factors:
age
h/o recurrence
antibiotic use
PPI use
#IBD

Tx:
πŸ₯‡ rec:
πŸ’Š fidaxo bid x15d
πŸ’Š fidaxo bid x 5d ➑️ qod day7-25
OR
πŸ’Š vanco 125mg QID pulse taper
βž•/βž– πŸ’‰ bezlotoxumab

πŸ₯ˆ rec:
Adjust IBD therapies to controlπŸ”₯
#FMT πŸ’©πŸ”¦
@halesj126 @MondayNightIBD @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD @AmCollegeGastro @wabillin 9/ To learn more about #CDI in #IBD

Join @DCharabaty for a #MondayNightIBDπŸ“½οΈBrunch w the expert @DrJessicaA

πŸ—“οΈAugust 8 @MondayNightIBD

We will talk how to position #CDI therapies in IBD, including #FMT, IV Bezlotoxumab & the new exciting micro biome-based πŸ’©therapies

β€’ β€’ β€’

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