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Aug 12 • 6 tweets • 2 min read
Al Musella, President, Musella Foundation for Brain Tumor Research & Information, Inc., a 501(c)3 nonprofit, re #DCVaxL : “ The results are outstanding.
Over 200% increase in the 5 year survival rate for newly diagnosed Glioblastomas as well as in the 30 month survival for recurrent Glioblastoma. There has been some unfair criticism of the trial on the internet -but watch the video and get the details directly from the source!
The same criticism happened after every major trial for brain tumors this century.
I used to think there were just people who could not grasp the details and we were just not explaining things right, but it turned out that it was just a few people trying to manipulate the stock market and has nothing to do with the actual science.
When you see anything about this or any trial - consider the source. If it is a financial blog, just ignore it!”

virtualtrials.org/newsblast.cfm?…
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More from @biosectinvestor

biosectinvestor Profile picture
Jun 22
Dendritic Cell Vaccine for Patients With Brain Tumors - Full Text View - ClinicalTrials.gov

#AdjuvantStimulus #PolyICLC

Ongoing #DCVaxL trial with Adjuvant stimulus, will likely further improve outcomes with #DCVaxL $NWBO clinicaltrials.gov/ct2/show/NCT01…
A trial with a combination #DCvaxL #PolyICLC and #Keytruda is already in process at UCLA. This is some of the early research on that combination $NWBO $MRK
Read 7 tweets
biosectinvestor Profile picture
Jun 21
Some quick thoughts on $NWBO and #DCVaxL. DCVaxL is designated an #OrphanDrug, for an #OrphanDisease, #Glioblastoma. This provides a bunch of benefits which are off topic for this thread.
My main point is to suggest that patients needing #DCVaxL may likely qualify for either of two funds in the UK, the #InnovativeMedicinesFund or the #CancerDrugsFund, which together have £640M allocated to provide early coverage to patients in the UK's NHS.
The UK charity, BrainTumorResearch.org recently put out a PR about the new program in the UK for rare diseases, which is modeled on an already existing program called the #CancerDrugsFund.
Read 32 tweets
biosectinvestor Profile picture
Jun 5
$NWBO never unblinded: 3/31/17 Opinion, Judge George J. Hazel, US District Court of Maryland, Southern Division, Motion to Dismiss, Granted - “Plaintiffs' additional argument that Defendants were trying to "bury" interim efficacy results is undercut by the record itself.
A review of the record in its entirety leaves as the only reasonable inference that the data monitoring committee had reviewed only safety data from the Phase III trials, not efficacy data.”
casetext.com/case/lerner-v-… Federal District Court Decision, Chad A. Lerner, Plaintiff vs Northwest Biotherapeutics, Defendant, p22.

Quote:
Read 20 tweets
biosectinvestor Profile picture
Mar 19
Let's explore a new accelerated pathway to licensing for new drugs in the UK #MHRA #ILAP
The MHRA Innovative Licensing and Access Pathway is open for business

The Medicines and Healthcare products Regulatory Agency (MHRA) today, 1 January 2021, formally starts the Innovative Licensing and Access Pathway (ILAP). #MHRA #ILAP

gov.uk/government/new…
Innovative Licensing and Access Pathway (ILAP)

"A new pathway supporting innovative approaches to the safe, timely and efficient development of medicines to improve patient access." #MHRA #ILAP

gov.uk/guidance/innov…
Read 13 tweets
biosectinvestor Profile picture
Jan 24
$NWBO #DCVaxL With regard to Dr. Roger Stupp being a consultant at $NWBO as they move toward the reveal of their top line data for Phase 3, publication and application to the FDA for approval, the BLA, adding him to the team I think is quite significant.
I made these points with other investors, so am sharing here.

This is ALL IMHO, and I own shares in $NWBO:
Since the Stupp Protocol established the Standard of Care (“SOC”) for the industry, and NWBO needs a placebo arm that is consistent with the Standard of Care, Stupp, being the father of the Standard of Care, now joining to advise and consult not only makes sense, it is…
Read 11 tweets

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