This world-leading scientist has dedicated himself to researching the effects of the SARS-CoV-2 coronavirus.
Now he calls it "the Satan bug" โฆ
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2) COVID DEBATE โฆ
"It's over"
๐ฃ๏ธ Sweden's Minister of Health, 2022-02-09
& many governments by now
โ vs. โ
"It's not over."
"I'm going to explain why now."
๐ง๐พโ๐ฌProfessor Jeremy Nicholson, 2022-02-10
Invited lecture at Uppsala University, Sweden
๐ฝ๏ธ:
3) JEREMY NICHOLSON BIO:
๐จ๐พโ๐ฌ Pioneered field of metabonomics, aka metabolic profiling
๐จ๐พโ๐ฌ Working towards high quality, inexpensive, personalised healthcare for all
๐จ๐พโ๐ฌ "100-100" aim: people live 100 years & 100 y healthy
๐จ๐พโ๐ฌ Led building of 15 'super laboratories' in 9 countries.
4) JN's SUPERLAB
๐ฃ JN is Director of Australian National Phenome Centre
๐ฃ ๐ฏ dedicated to C19 since Feb 2020
๐ฃ 10,000s C19 blood samples from ๐
"We bring this incredibly comprehensive biochemical view of the disease & coupled with the best samples in the world."
๐ง๐พโ๐ฌJN Oct'20
5) OBJECTIVE MEASUREMENTS OF COVID'S EFFECTS
E.g. JN does box plots for 6โฃ0โฃ0โฃ blood chemical concentrations (or conc. ratios):
๐ Vert axis is conc
๐ Each dot is a sample meas
๐ Box vert pos+size shows conc spread
โคต๏ธ 9 example plots, a-i
๐ฉ=no C19
๐ฅ=acute C19
๐ฆ=3 months on
6) ๐จ COVID-19 ACUTE
"The thing that makes it unique, is it has a multiple system failure signature.
It stands out like a sore thumb.โ
๐จ๐พโ๐ฌJN, Aug'20
๐ง
โคต๏ธ All 9 example blood chemical concentrations (& many not shown) are perturbed:
๐ฅ=C19acute is either above or below ๐ฉ=noC19
7) ๐จ COVID-19 LONG TERM
"Very few people, even at 6 months, have actually metabolically, functionally recovered.
They may have stopped coughing but they've still got a lot of other things wrong with them.โ
๐จ๐พโ๐ฌJN, Novโ21
๐ง
โคต๏ธ E.g. d still perturbed:
๐ฆC19+3mth is below ๐ฉnoC19
8) ๐จ COVID-19 IN CHILDREN
Children have milder respiratory symptoms BUT โฆ
โWhen we look at the biochemistry, itโs just as seriously affected as in adults."
๐ง๐พโ๐ฌProf. Jeremy Nicholson, 2022-04-02
"An absolutely unprecedented disease in terms of its complexity, but also because of its unique economic coupling which has crippled the world."
[2020-10-05]
"Itโs the closest thing weโve ever seen in modern times to a real threat to humanity."
[2021-06-19]
13) JEREMY NICHOLSON & THE SATAN BUG โฆ
In COVID-19 lectures, JN shows a 1965 movie poster that he has scrawled on in red ink, & reads it out.
โAs far as I'm concerned, SARS-CoV-2 is the Satan bug.โ
๐ด Epidemic grows exponentially when each infected person infects 2-3 others on average (R~2.5); but dies out if on average infects less than one other (R<1).
๐ด #TestTraceIsolate of *symptomatic* cases & their contacts helps (Rโฌ๏ธ) but typically not enough. However...
2/n
โ COVID-19 is also readily detectable in the stool ๐ฉ & in sewage.
๐ก Search using sewage network -- to quickly & systematically find & isolate ~all infected.
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