PUBLISHED. We have just published our 2nd large study of the effects of ivermectin as prophylaxis for COVID-19 in Itajaí, Santa Catarina, Brazil. Link: cureus.com/articles/11185…
While in the 1st study we evaluated whether the use of ivermectin could impact in COVID-19 infection and mortality rates, in this study we evaluated whether the regular use and the total amount of ivermectin used could bring additional benefits.
We observed that among who used ivermectin, those who used ivermectin regularly every 15 days at a dose of 1cp of 6mg for every 30kg of body weight for 2 consecutive days for at least 6 to 8 weeks had up to a 92% reduction in mortality compared to those who did not.
We showed a dose-response effect, that is, the more you used, the more protection you had, which reinforces the conclusions regarding ivermectin efficacy.
In the 2nd study, I acted as the senior researcher, that coordinated and headed the analysis of the study. I am honored to have led the analysis of the study designed by the great Prof. Lucy Kerr.
I, Flavio Cadegiani, have afforded all editorial costs without receiving absolutely any additional penny for these purposes.

I hope you enjoy the reading.

Flavio Cadegiani

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More from @FlavioCadegiani

May 1, 2023
The 04 science-abusive behaviors that have been spread during COVID-19, and that everyone should become aware of. Suggested by me, one of the persons that most suffered these pathological behaviors. Imperative reading. (thread)
1. Sciencesplaining is when a non-scientist explains to a true scientist or expert in the field what science is, or, even worse, that the science a scientist tries to explain is not science.
This usually comes with media- and organizations-supported Dunning Kruger effect for a… twitter.com/i/web/status/1…
2.Sciencelighting is the phenomenon of a non-science expert person from a mainstream voice to undermine the work of a scientist, by manipulation in a negative manner the quality of the work, belittling it, fabricating false doubts regarding her/his research, added by extrapolated… twitter.com/i/web/status/1…
Read 5 tweets
Sep 8, 2022
VEJAM COMO FUNCIONA UMA “AGÊNCIA DE CHECAGEM”. Leiam a troca de e-mails. Cada e-mail estará em um Tweet neste thread. Trata-se do estudo que publicamos de IVM. Vejam que eu ainda admiti um erro e dei uma excelente chance. Pedi um jornalismo justo. Não aceitaram. Segue. 1o e-mail:
2o e-mail (minha 1a resposta - ah, as perguntas foram boas e eram extremamente fáceis de serem respondidas - mas o intuito, como verão, não era o de esclarecer):
3o e-mail (resposta do editor):
Read 11 tweets
Sep 6, 2022
An example of a highly biased quote bothered person with our work. Inability to interpret a study - have no idea of what a conservative bias is. This person truly thinks I make billions of dollars over te drug sales. Of course, these would’ve never been asked to other drugs…
Just to teach you: 1. If someone is not using ivermectin in the ivermectin group: false reduction of its efficacy - it’d be even better if this didn’t happen; 2. ALL major confounded addressed; and 3. “Terrible” and “embarrassing” are feelings, not science.
Thankfully we had a truly unbiased technical analysis. This is a desperation of someone with strong beliefs and weak (real) science. I hope everyone learns.
Read 4 tweets
Sep 3, 2022
Testosterone and COVID-19 - a brief message

A recently published study says low testosterone is associated with greater severity of COVID-19. Study made to confuse because it mixed pre with post COVID (1 month of window only), with authors sponsored by…Pfizer!
They pretended that our studies did not exist, made an extreme, forced cherry-picking selection and had a clear objective: to refute the anti-androgenic theory. Here is the link:

jamanetwork.com/journals/jaman…
Let's explain:

1. Testosterone dosed before COVID-19 can be related, inversely related, or unrelated. The only study that dosed testosterone before COVID-19 showed a direct relationship between testosterone and severity: pubmed.ncbi.nlm.nih.gov/35536887/
Read 11 tweets
Sep 3, 2022
Testosterona e COVID-19 - uma mensagem

Estudo da Pfizer (🤡🤡🤡) diz que testosterona baixa está associada a maior gravidade de COVID-19. Estudo feito para confundir porque misturou pré com pós COVID, com autores patrocinados pela…Pfizer!
Fingiram que nossos estudos não existiram, selecionaram aí bem prazer e tinham claro objetivo: refutar a teoria anti-androgênica. Aqui o link: jamanetwork.com/journals/jaman…
Vamos explicar:

1.Testosterona dosada antes da COVID-19 pode ter relação, relação inversa ou não ter relação. O único estudo que dosou antes da COVID-19 mostrou relação direta entre testosterona e gravidade: pubmed.ncbi.nlm.nih.gov/35536887/
Read 12 tweets
Aug 31, 2022
PUBLICADO. Acabamos de publicar o 2o grande estudo dos efeitos do uso de ivermectina como profilaxia para COVID-19 em Itajaí, Santa Catarina. Link: cureus.com/articles/11185…
Enquanto no 1o estudo avaliamos se o uso da ivermectina poderia impactar na taxa de infecção e mortalidade, neste estudo avaliamos se o uso regular e a quantidade total usada de ivermectina poderia trazer benefícios adicionais.
Nós observamos que dentre os que usaram ivermectina, aqueles que usaram ivermectina regularmente a cada 15 dias na dose de 1cp de 6mg a cada 30kg de peso corporal por 2 dias por ao menos 6 a 8 semanas tiveram redução de até 92% na mortalidade comparado com quem não utilizou.
Read 6 tweets

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