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Sep 28 • 4 tweets • 2 min read
This guy has me totally convinced that we have a problem with science communication.

#SciComm #WissKomm
Context:
More context:
Essential context for those who don't know @PhilippMarkolin:

protagonist-science.medium.com

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More from @CD57227

CD Profile picture
Sep 28
Stuart's promoting @WashburneAlex's great article on substack. A good reason to read it!

alexwasburne.substack.com/p/how-to-inves… Image
@WashburneAlex Excerpt: "... it is unlikely that these knowledgeable people, after jumping on a call together with all their minds in a room alongside Fauci and Farrar, would make such obvious undergraduate mistakes on such a visible and critical matter concerning the origin of a virus..."
"If Usain Bolt suddenly ran a 50 yard sprin[t] in 40 seconds, I would think something is up and I would need to ask Usain Bolt 'Why are you doing such poor sprinting today?'"
Read 4 tweets
CD Profile picture
Jul 27
Laborthese wird immer noch unwahrscheinlicher. Ja, wie unwahrscheinlich kann sie denn überhaupt noch werden?

Frühjahr 2021: "extrem unwahrscheinlich"
Sommer 2022: "noch viel unwahrscheinlicherer!"
focus.de/gesundheit/new…
Read 15 tweets
CD Profile picture
Jul 25
In his PhD thesis (2014), Markus Hoffmann tested proteolytic cleavage and fusogenicity of a bat SARS-like virus.

He had two spike proteins at his disposal:

BM48-31 (aka Bg08)
BB99-04 (aka "Whoa, this thing has sort of a furin cleavage site!" [Drosten])

Which one did he choose?
Well, obviously he chose...
For hints, see: repo.uni-hannover.de/handle/1234567…

Pg. 132-135
Pg. 207-209
Read 8 tweets
CD Profile picture
Jul 15
Raccoon dogs and SARS-CoV-2

Quick thread 🧵on media articles and studies.
March 4th, 2020

In his podcast, Drosten dismisses the idea of pangolins as intermediate hosts.

But, he says, racoon dogs 🦝 may have played a role in SARS-1, and so also may play a role here!

"They are an industry in China."
ndr.de/nachrichten/in…
April 26th, 2020

Drosten is interviewed by The Guardian, says the *media* overlooked raccoon dogs:

"[SARS-1] was found in civet cats, but also in raccoon dogs – something the media overlooked."
theguardian.com/world/2020/apr…
Read 27 tweets
CD Profile picture
Jun 6
@gdemaneuf @c_drosten @MonaRahalkar @ydeigin @JamieMetzl @Biol4Ever @R_H_Ebright Fantastic thread 🙏

I think their bat CoVs are interesting:

Original publication was in 2010, when journals.asm.org/doi/10.1128/JV… came out.

But only BM48-31 was submitted to Genbank by then.

All others were submitted in 2013.
Except BB99-04, which wasn't even in the 2010 publication
@gdemaneuf @c_drosten @MonaRahalkar @ydeigin @JamieMetzl @Biol4Ever @R_H_Ebright It was submitted in 2015, by the Primate Center in Göttingen, with an accompanying unpublished article with an interesting title:

"Differential restrictions in the receptor-binding and *fusion activity* of the surface protein S of European SARS-like CoVs"
@gdemaneuf @c_drosten @MonaRahalkar @ydeigin @JamieMetzl @Biol4Ever @R_H_Ebright * small correction:

RdRp was submitted in 2013 by Uni Bonn (KC633202)
Spike was submitted in 2015 by German Primate Center (KR559017.1)
Read 5 tweets
CD Profile picture
Jun 5
Zoonati in 2020:

"Everything's been published before the pandemic! There are no 'secret' SARS-like sequences that people are working on!"

Drosten in 2022:

"Here are some very interesting spike sequences we didn't publish! Never before seen! Samples were collected in 2008." 🤦‍♂️
doi.org/10.1038/s42003…
June 2021: "So that's what science is all about. It's not about keeping anything under wraps and hiding it. Why should you put years of work into something that no one will ever know about?"
ndr.de/nachrichten/in…
Read 6 tweets

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