Thread by @GasBugZa

During the afternoon session on nutrition, Dr Nadiya Ahmed will be speaking about 'Hitting the nail on the head, iron supplementation in the ICU'.
#CCSSA2022 #critcare #FOAMcc

Iron has many functions including O2 delivery, in myoglobin (O2 storage in muscles) and metabolism (cytochromes). Iron metabolism in critical
doi.org/10.1186/cc9992
#CCSSA2022

Oral formulations have systemic side effects (GI side effects) whilst older IV formulations have a risk of anaphylaxis.
#CCSSA2022

In critical illness, the worry is that iron supplementation increases the risk of sepsis. Iron sequestration in illness is thought to be adaptive, but probably becomes maladaptive at extremes.
doi.org/10.1016/j.jcrc…
#CCSSA2022

The ESPEN micronutrient guidelines come up again, which state that IV iron should be given to critically ill patients with demonstrated low iron levels (as evidenced by low hepcidin levels).
doi.org/10.1016/j.clnu…
#CCSSA2022