2/ The study region has no #REBOA or prehospital resus thoracotomy services. 90.1% of TCA were prehospital with 64.8% from blunt injuries. Only 6.7% had shockable rhythm.
29.9% survived to ICU with mean days on ventilator of 3d. Only 10% survived to 30 days (GOS 3 or 4 mostly).
3/ In-hospital TCA had a much higher chance of survival (42.9% vs 7.0%) - but remember there is no prehospital thoracotomy/aortic compression/REBOA services, therefore I'm not sure how applicable this data is if setup were different. @viseshsankaran@traumakhan@WilsonMSJ
4/ Cause of death within 24h was mainly due to bleeding (60.2%), whilst mortality after 24h were mainly related to #TBI (not specified as to whether this may actually be hypoxic brain injury). *Prehospital chest compressions did not alter mortality rates*, as expected..
5/ For in-hospital TCA cases, survival was predicted by presence of pupillary response, higher platelets and fibrinogen, higher pH but lower lactate, base deficit and S100b.
Of the 36% who underwent resus thoracotomy, timing was crucial (9.5min for survivors vs 23min).
6/ Overall survival (and functional outcome) for #TCA remains poor but possible, especially with improving time to thoracotomy. No differences were seen between #blunt vs #penetrating injuries.
It would be interesting to see data from prehospital interventions.
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2/ This 9-year prospective observational study included 490 #IIH patients in @uhbtrust with 98% being female (F:M was 53:1) with mean BMI 38, as defined by papilloedema (Frisen grade >0) in at least one eye. 67.1% required multiple hospital visits. 87% were treated medically.
3/ Medical treatment most commonly used included acetazolamide (27%) and topiramate (9%). #IIH relapse occured in only 3.7%. Ocular outcome mirrored reduction in ganglion cell layer (GCL) vol, perimetric mean deviation (PMD) and retinal nerve fibre layet (RNFL) on OCT.
Case study as #MorningPaper to start off the week. 27y cyclist vs car, GCS 15, CSF rhinorrhoea. CT attached. What are the steps of your management plan? What kind of injuries are you seeing?
My decision here: Lumbar drain initially for yeh CSF leak, Pneumovax but not antibiotics. Lefort III fracture and mandibular needs surgery so planned to cranialise frontal sinus at the same setting. Consent included fascia lata and calvarial grafts, just in case. 1/🧵
2/ #Submental intubation to gain better oral access: cut down onto inferior border of mandible, blunt dissection with artery clip through floor of mouth, dilators and then deliver ETT submetally and reconnect.