Did you know that #HydraulicForces:
✅are related to the relative size of the LA in relation to the LV?
✅contribute to left ventricular diastolic function?
✅associate independently with survival?
Myocardial #stiffness and #damping are mechanistic ⚙️properties of the LV that can be estimated by measuring the Doppler 🔊 E wave peak velocity, acceleration time ⏲️, and deceleration time ⏲️.
The physics governing the recoil of a spring are well described as a damped harmonic oscillator, and it is well validated that the Doppler E-wave is governed by these same physics, aka parameterized diastolic filling (PDF) [pubmed.gov/3812709]. 2/n
This means that the shape of the E-wave can be excellently curve fit to a function that describes the behavior of a damped harmonic oscillator. Figure from pubmed.gov/33066772 3/n