For #EchoFirst measure of the LV, LA, aortic size, what is the best body size measure to index by?

New paper (PMID 37938592): We used CV mortality in 200,000+ pts in the Natl Echo Database Australia #NEDA to determine the best indexation measure.

🧵

1/n First question - does any body size indexation improve the prognosis of echocardiographic measures?

Answer: Yes

2/n

What's the best 🫀 imaging method to detect & quantify pulmonary hypertension?

Just out in JACC Cardiovasc Imaging:

Ramos JG, et al, "Pulmonary hypertension by catheterization is more accurately detected by #WhyCMR 4D-Flow than #EchoFirst"

🧵 Firstly, starting back in 2008, co-authors Gert Reiter and Ursula Reiter pioneered the method for estimating mPAP by vortex duration by #WhyCMR #4Dflow.

#EchoFirst & diastolic dysfunction - what do you know about:
✅hydraulic forces
✅myocardial stiffness
✅damping

Learn more in this talk I recently gave at Echo Australia 2022.

🫀🔊
#BoingBoing

Did you know that #HydraulicForces:
✅are related to the relative size of the LA in relation to the LV?
✅contribute to left ventricular diastolic function?
✅associate independently with survival?

Do you routinely measure #MAPSE?

Did you know that MAPSE beats #GLS and #LVEF regarding prognosis?

A new multicenter collab study out, led by @KellmanPeter

Ref:

#WhyCMR 🫀🧲 #EchoFirst 🫀🔊

A thread 🧵. 1/n pubmed.gov/35132872
We know that GLS is a composite measure correlated w LVEF, LVEDV, LVESV, LV mass, infarction, non-ischemic scar, aortic stenosis, mitral regurg, ECV.

So, not surprisingly, GLS associates with poor prognosis.

Ref: Suppl Table 2

2/n pubmed.gov/32563637

When it comes to LV diastolic (dys)function, let's think of the LV like a spring, which is compressed during systole, and recoils during diastole.

A thread 🧵
1/n

@strain_rate @load_dependent @DrWillWatson @shaunrobinson02 @leoshmu

https://twitter.com/strain_rate/status/1321203458079367170

The physics governing the recoil of a spring are well described as a damped harmonic oscillator, and it is well validated that the Doppler E-wave is governed by these same physics, aka parameterized diastolic filling (PDF) [pubmed.gov/3812709].
2/n