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Lazarus Long Profile picture
@LazarusLong13
Nov 5, 2022 • 19 tweets • 10 min read • Read on X
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Another absolutely horrible take by #FireWalensky, @CDCgov

“If you go two years without getting that infection, without getting that protection from infection and then all of a sudden, boom, everybody from zero to three years gets RSV, you see the impact on health care.”
Except. That's NOT WHAT the data shows

As we can see, the biggest spike is in 0 to 6 months, and in comparison to 2018-2019, it is much greater. Roughly, per 100k, 130 versus 70, and it is still spiking.

Second biggest spike is in 6 to 12 months, at almost 80, versus 30 at
its highest.

In the 1 to 2 year olds, almost 40 this year vs. almost 20.
(The Y-axis is higher this year because of more cases).

If what Walensky is saying was true, we'd expect to see the 2 to 4 year olds screaming higher.

It's not.
But the big hitter was the zero to 6 months. What happened there?

Walensky's immunity silliness simply is irrelevant.

But this is relevant:
She really will do everything in her power to minimize CoVid, won't she?

Free version of that article here!
archive.ph/gRg9p

RSV dashboard is here - play with it, see what else you can find

cdc.gov/rsv/research/r…
This is Jose Romero, director of the NCIRD at the @CDCgov.

Jose is not thinking clearly. Has he been infected?

Why do I say he's not thinking clearly?
At the most recent CDC briefing, Jose was asked, why RSV is spreading so quickly and early.
"So we’re seeing more RSV because in the last past two years, we’ve not seen infections in children as we have previously. And so these children, if you will, need to become infected to move forward because it’s a disease very common in children. "

Literally, the XKCD comic.
But the same problem exists.

The biggest spike in hospitalizations is in the babies. 0-6 months and 6 months to 2 years. And the 0-6 months was the BIGGEST spike.

What could cause hospitalizations in that group?

Well, first what causes RSV hospitalizations?

"Pre-F antibody titers were significantly lower in mothers whose infants were hospitalized with RSV bronchiolitis compared with those mothers whose infants were not hospitalized..."

academic.oup.com/jid/article/22…
So, maternal antibodies are important. Could the maternal antibodies have not been passed on because the mother did not get infected?

Fortunately, 95% of people are exposed by the time they are two, so the mother would not have had to be exposed to pass on those antibodies.
Can you imagine?

"Now that you are pregnant, let's schedule your infections. First trimester, we'll do RSV and Ebola."

Silliness.

Let's take another look at that preprint that @fitterhappieraj found

Every infant inherits their microbiome from their mom, and mom's
microbiome diversity was reduced by Covid.

And we know those infants had a unique microbiota, per above, compared to Covidians (those infected).

Indeed, SARS-CoV-2 infections during pregnancy are associated with a compromised initial microbial seed of the infant.
No big deal, right?

Wrong.

"The inherited microbiome exerts marked effects on immune programming with long-term health consequences, including susceptibility to infections or chronic inflammatory diseases and reduced vaccine efficacy"
"Therefore, this “window of opportunity” at birth, either renders infants with a healthy immune system or alternatively establishes a divergent path leading to severe immune-mediated disease susceptibility (16-24). "

Well, that sounds like pediatricians are going to be busy.
To be crystal clear, this study is NOT saying that Covid is responsible for the increase in RSV.

But it is saying Covid causes negative changes at a very important moment in the baby's life, immunologically speaking.

And since we are talking about more severe RSV cases?
It seems to be directly related.

Or, at the very least, much more plausible than a concept invented last year. A concept that Fox & Friends has been pushing.

Was it bleach they last pushed? Or herd immunity?

In any event, both Walensky and the director of the CDC are also
pushing immunity debt like universities pushing student loan debt.

Someone needs #FireWalensky, and put Jose on notice.

@CDCgov? That microbiome spoiled once #FireWalemsky got hold of it.

Maybe probiotics could save the #xkcdCDC. Maybe.
The RSV surge in the 0-6 month old babies, which eliminates "immunity debt/gap" as a viable hypothesis?

Will have very real consequences down the road. This is not surprising given measles ability to wipe out immune memory

frontiersin.org/articles/10.33…

H/t @Gene_PHL @Comm_in_Care

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More from @LazarusLong13

Lazarus Long Profile picture
Feb 5
This is a very big deal. D1.1 now in cattle.

D1.1 has put 100% of the people it has infected into the hospital - and killed 50%.**

BC teen had to be intubated on ECMO - despite age and no preconditions.

Louisiana man died in the hospital.

aphis.usda.gov/news/program-u…On January 31, 2025, the USDA Animal and Plant Health Inspection Service (APHIS) National Veterinary Services Laboratories (NVSL) confirmed by whole genome sequence the first detection of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b, genotype D1.1 in dairy cattle.
** The numbers of those severely impacted SHOULD drastically go down as doctors become aware of the importance of ruling out H5N1 much quicker.

The teen had delayed care, and that is one possible reason for the severity of their infection.

** We need more numbers infected to
see if the severity is truly wide-spread - or did we just have a couple of very unlucky people.
Read 5 tweets
Lazarus Long Profile picture
Jan 30
What Have You Got Against A Mask?

1/9 What Have You Got Against A Mask? In a black and white photograph, a black woman wearing a white duckbill respirator, gazes deep into your soul. Her eyes tell you that .... The simple act of wearing a respirator (KN95, N95, or better) can save your life, if they're used properly and every time you are in a public place / outside your home. Wearing a mask helps prevent transmission of airborne viruses such as SARS-CoV-2, RSV, influenza, and more. Despite profit-based claims otherwise, we are still in a global COVID pandemic. Mask up to protect yourself and others from illness, disability...
What Have You Got Against We, The People? A DELTA plane landing on their words that have killed thousand. Disabled hundreds of thousands, and destroyed us all. We are writing on behalf of Delta Air Lines to the Centers for Disease Control and Prevention (CDC) to reconsider the current guideline for 10 days of isolation in fully vaccinated individuals who experience breakthrough COVID-19 infections... We propose a 5-day isolation from symptom onset for those who experience a breakthrough infection. Delta Airlines to CDC Director, Dec. 2021 THIS IS TO ENRAGE YOU.
What Have You Got Against A Mask? In a black and white photograph, a young teenager stares into your soul. His eyes say, What Have You Got Against A Mask? The simple act of wearing a respirator (KN95, N95, or better) can save your life, if they're used properly and every time you are in a public place / outside your home. Wearing a mask helps prevent transmission of airborne viruses such as SARS-CoV-2, RSV, influenza, and more. Despite profit-based claims otherwise, we are still in a global COVID pandemic. Mask up to protect yourself and others from illness, disability (Long Covid), and death. For more information about...
Read 9 tweets
Lazarus Long Profile picture
Jan 28
This may be the biggest news of the decade. Completely overshadowed by shenanigans in the White House.

It looks like H5N1 reinfections are entirely possible. This means that our farms are going to be a never-ending circulating pump of H5N1.

This. Is. Not. Good.

/1 But reinfections suggest that the virus, called H5N1, could circulate on farms indefinitely, finding opportunities to evolve into a more dangerous form — a “high-risk” scenario, said Louise Moncla, an evolutionary biologist at the University of Pennsylvania. “You could easily end up with endemically circulating H5 in dairy herds without symptoms, obscuring rapid or easy detection,” Dr. Moncla said.
How long can our luck go on?

We now have Bobcats with the one mutation that we really don't want to see.

The PB2 E627K mutation.

"The PB2 E627K mutation is a dominant adaptation marker in most human-adapted influenza A viruses. " PB2 E627K is a mutation in the PB2 gene of the influenza A virus that changes the amino acid glutamic acid (Glu) to lysine (Lys) at position 627. This mutation helps the virus replicate more efficiently in mammalian cells. How it affects the virus Replication: The PB2 E627K mutation helps the virus replicate more efficiently in mammalian cells. Disease severity: The PB2 E627K mutation can cause more severe disease in mammals. Temperature: The PB2 E627K mutation helps the virus replicate in the lower temperatures of the upper respiratory tract of mammals. How it affects humans Human-adap...
Read 9 tweets
Lazarus Long Profile picture
Jan 14
If you are taking public transport like in NYC? Mask up.

Pretty cool Master's Thesis for Biology - on bioaerosols like SARS-COV-2.

Set up a prototype aerosol sampler?

And find it in 52.9% of the samples in Beijing Railway Station and 44.4% at Beijing Subway Station.

/1 The subway station selected for this experiment was Xidan Subway Station, a major subway station on Lines 1 and 2 in Beijing and serves as an important subway transit hub. The passenger flow of the station is expected to be around 7,000 – 12,000 during rush hours and less than 7,000 during non rush-hours. A total of 27 samples have been collected, with the first 10 collected around 9-10am in the morning or 3-4pm in the afternoon, which is considered non-rush hour and 17 collected during the rush hour period. Sampling was collected for 17 weeks in total, not necessarily consecutively taking ...
Bioaerosol Sampling in the Exit Area of Beijing Railway Station. BC500 was placed near the exit area of the Beijing Railway Station where passenger flow is expected to be the largest. Beijing Railway Station is one of the oldest train stations in Beijing with a large passenger flow that is around 60,000 passengers per day. The bioaerosol sampling device in this scenario is placed at the exit area of the train station, where passenger flow is relatively higher, ensuring better chances of sample collection. However, passenger flow, unlike the subway station is not divided into rush / non-rus...
Never mind this.

"Firstly, the high positive rate highlights the potential for airborne transmission of these viruses in crowded public areas"

Definitely do not flag this to anyone in a big city looking to ban masks.

Definitely do not do that with this new study. The findings of the experiments conducted in this thesis indicate that viruses including SARS-CoV-2 and influenza are not only present but also potentially widespread in these public spaces, which has several important implications. Firstly, the high positive rate highlights the potential for airborne transmission of these viruses in crowded public areas. This is consistent with existing literature that suggests densely populated environments with limited ventilation can facilitate the spread of respiratory viruses. The detection of multiple pathogens reinforces the importance of considerin...
Yes, nothing to see here.....

At Beijing Railway Station, positive samples were
52.9% SARS-CoV-2
47.1% Flu A
23.5% Flu B.

At Xidan Subway Station, positive samples were
44.4% SARS-CoV-2
18.5% Flu A
7.4% Flu B At Beijing Railway Station, 52.9% of samples tested positive for SARS-CoV-2, 47.1% for influenza A, and 23.5% for influenza B. Additionally, 29.4% of the samples were positive for two pathogens, and 11.8% were positive for all three pathogens. The total percentage of negative samples at this location was 29.4%. At Xidan Subway Station, 44.4% of the samples tested positive for SARS-CoV-2, 18.5% for influenza A, and 7.4% for influenza B. Moreover, 18.5% of the samples were positive for two pathogens, with no samples testing positive for all three pathogens. The total rate of negative samples ...
Image
Read 5 tweets
Lazarus Long Profile picture
Dec 31, 2024
Sara Anne Willette's visualization tool - is not a list. It is a visual representation of a group of accounts, so that she can remove herself from them.

It uses only publicly facing data, available per the X TOS, and the API, not scraping.

IT WILL NOT EFFECT YOU AT ALL. Image
Image
There are some accounts 👇 and their followers that SHE JUST WANTS NOTHING TO DO WITH.

It is her choice to remove herself from any account she wants.

The actual data?

✔️ account creation date
✔️ the username of the account,
✔️ who they follow.

All obtained legally per TOS. The list. Ooo so scary. You all are acting like high school kids.
Describes user name
The LOCATION that you saw in the blurry used to get you all fired up!?

Picked up from the front page of the profile, but NOT USED.

I live in Temporarily Enabled, USA - but it is not my physical location.

That's it.

Some additional thoughts, from me, not Sara. Not using location
Read 18 tweets
Lazarus Long Profile picture
Dec 23, 2024
Ozone. A pollutant no matter where it is - outdoors or indoors.

#DYK that indoor inhalation is 25% to 60% of total intake? Per Weschler?

iaqscience.lbl.gov/increases-ozone

#DYK that MOST indoor ozone comes from OUTDOORS? Per Weschler?

pmc.ncbi.nlm.nih.gov/articles/PMC16…

Truly worried?

🧵 Accounting for the differences between indoor and outdoor air ozone concentrations, Weschler [6] has estimated that indoor exposures to ozone are typically 45% to 75% of total exposures. Because breathing rates are lower when people are indoors, the indoor inhalation intake of ozone is typically 25% to 60% of total ozone intake. These estimates may be low for the population most affected by ozone—infants, the elderly, and those with respiratory and cardiovascular disease. Consequently, if there is no threshold concentration for the health effects of ozone, or if the threshold is low, roughl...
Although there are indoor sources of ozone, in most buildings indoor ozone has been transported from outdoors (Weschler 2000). Indoor ozone concentrations track outdoor concentrations with a slight time lag that depends on the air exchange rate. Ozone is removed by indoor surfaces as well as by gas-phase reactions, and hence, indoor concentrations tend to be smaller than co-occurring outdoor levels.
If you are TRULY worried, you should be focused on eliminating ozone, right?

You would be slipping into people's threads and sharing these cheap DIY activated carbon builds, right?

Because if you are TRULY concerned about ozone, you would not be slipping into threads of people showing pictures of their new FAR-UVC Torches - for any other reason, but to share the good word that the miniscule ozone generated could be eliminated.

VIRUS and OZONE free air.
Read 8 tweets

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