Dr John E. Canuck Profile picture
Nov 15, 2022 40 tweets 12 min read Read on X
This far into the pandemic there is no excuse for denying masks reduce the transmission of COVID-19. I’m making this thread to be a quick reference of the evidence so you can refer people here if you find yourself faced with the claim “masks don’t work.”
Article published in JAMA in 2/2021 detailing how masks work to reduce community transmission. Include a nice table summarizing 11 studies at the time. jamanetwork.com/journals/jama/… Image
A study from JAMA in 7/2020 of almost 10,000 healthcare workers showing universal masking in the healthcare setting decreased cases. jamanetwork.com/journals/jama/…
Large systematic review and meta analysis from the Lancet in 6/2020 showed masking reduced transmission (as well as social distancing and eye protection). thelancet.com/journals/lance…
Another systematic review and meta analysis from the American College of Cardiology in 9/2020 showed significant reduction in transmission for both healthcare and non-healthcare workers. acc.org/latest-in-card…
A cross-sectional study in the Lancet from 1/2021 showed face masks and physical distancing reduced transmission. thelancet.com/journals/landi…
From JAMA now in 2/2022 masks cut secondary transmission in half.
jamanetwork.com/journals/jama/…
I found this to be a nice summary at the time (8/2020) from BYU on “Making Sense of the Research on COVID-19 and Masks.” pws.byu.edu/covid-19-and-m…
This was also a nice informative article at the time (4/2020). Keep your droplets to yourself. fast.ai/posts/2020-04-…
Nice one from Science 5/2021 discussing how masks limit transmission probability especially if combined with distancing and hand hygiene. science.org/doi/full/10.11…
Nice study from 5/2022 showing direct mask wearing (as opposed to prior studies of mask mandates) reduced transmission. pnas.org/doi/10.1073/pn…
And another all the way back from 12/2020 showing masks reduce transmission. pnas.org/doi/10.1073/pn…
Large study from Standford in 9/2021 showing surgical masks can reduce transmission. med.stanford.edu/news/all-news/…
Another systematic review this one from 1/2021 frontiersin.org/articles/10.33…
Andddd another systematic review this one from 7/2021 sciencedirect.com/science/articl…
This study in preprint from 11/4/2022 showing mask policies reduced transmission rates. medrxiv.org/content/10.110…
A study showing even after high levels of transmission adoption of mask wearing reduces spread and death. medrxiv.org/content/10.110…
Wearing a mask in care homes reduced spread. academic.oup.com/ije/article/50…
Another systematic review from 7/2022, surprise surprise, masking reduced transmission. medrxiv.org/content/10.110…
Fabric masks better than nothing? 🤷‍♂️ tandfonline.com/doi/full/10.10…
What about schools? Well new article from 11/9/22 in the NEJM shows it can help. nejm.org/doi/full/10.10…
Study from the AAP 5/20/2022 publications.aap.org/pediatrics/art…
Adding this study from 10/2022 showing masking in classrooms slowed the spread. mdpi.com/1660-4601/19/2…
Of course need to add this study from 8/2022 on school masking requirements that made the rounds all over Twitter at the time. medrxiv.org/content/10.110…
Adding this study from 10/6/22 showing masking continued to be helpful even with Omicron. ajicjournal.org/article/S0196-…
And because this keeps coming up in the comments here is a RCT study from February 2009 showing *proper* mask use was associated with a 60-80% reduction in transmission of influenza like illnesses. ncbi.nlm.nih.gov/pmc/articles/P…
And another RCT from February 2010 showing masks and hand hygiene reduced influenza like illnesses. pubmed.ncbi.nlm.nih.gov/20088690/
A nice companion article to the above study: academic.oup.com/jid/article/20…
This is such a great article that covers a little bit of everything. The section on masking is definitely worth reading. sciencedirect.com/science/articl… ImageImage
Paper also has a nice section on Misinformation. sciencedirect.com/science/articl… ImageImage
Adding this paper from Nature 12/2/22 because masking reduces exposure to and spreading of higher viral loads. Lower viral loads = less transmission. Mask up. Bonus points because vaccination also reduces peak time of viral loads. nature.com/articles/s4157… Image
Adding this study from April 2020 showing surgical face mask use can lower both influenza and coronavirus in aerosols. Mask up this season people.
nature.com/articles/s4159…
Clinical review from the BMJ in 2015 looked at 9 studies with all but one showing masks or masks plus hand hygiene can lower transmission of respiratory viruses. bmj.com/content/350/bm…
Study from 2009 showing both N95 and surgical masks reduced spread of influenza. academic.oup.com/cid/article/49…
Study from 2013: Surgical masks worn by patients reduce aerosols shedding of influenza virus. journals.plos.org/plospathogens/…
Study from 5/2011 showing N95s gave superior protection against respiratory viruses. pubmed.ncbi.nlm.nih.gov/21477136/
Study from 1/11/23 out of BC found face mask impacts were greatest in restaurants, bars, cafés, and retail locations. publichealth.jmir.org/2023/1/e42616
Nice update from this past fall reviewing the evidence for mask wearing to prevent COVID. After review call on the ice stands, masks work. ncbi.nlm.nih.gov/pmc/articles/P…

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More from @DrCanuckMD

Jun 4, 2023
What is a Woman is trending so I think it’s important to spread the word that transitioning leads to improved quality of life, greater relationship satisfaction, higher self-esteem, and reductions in anxiety, depression, suicidality, and substance use. Mega 🧵 to bookmark. Image
Read 43 tweets
Jun 2, 2023
People got really upset when I said mRNA vaccination has not been shown to cause blood clots. Some acted like if I showed them proof they’d change their minds (because they definitely weren’t sealioning). Well ok. Here’s a 🧵 to share if you see ppl trying to blame mRNA vaccines.
Large study early on examining risk after the first dose of Pfizer found no increased risk of thrombotic events. nature.com/articles/s4159… ImageImageImage
Follow up study examining risk after the second dose. Uh, still no increase risk. nature.com/articles/s4146… ImageImage
Read 16 tweets
Jun 1, 2023
Quick thread on vaccine associated myocarditis. We’ve known for 2 years this is a possible rare side effect. Particularly in adolescent and young males. The vast majority of cases being mild with sometimes short uneventful hospital courses. 🧵 ImageImageImage
Of the cases that do develop, follow up testing such as echocardiograms and cardiac MRIs are reassuring suggesting favorable long term outcomes. Link: ncbi.nlm.nih.gov/pmc/articles/P… ImageImage
I’ve seen some try to argue vaccinating young men was unethical. Early on, particularly with alpha and delta circulating, the risk benefit discussion was clear. The benefits far outweighed the risks. ncbi.nlm.nih.gov/pmc/articles/P… ImageImageImage
Read 8 tweets
May 19, 2023
Gender is not binary and transgender individuals are not suffering from some mental illness or “choosing” a different identity for fun. If you’re going to spend time on Twitter attacking transgender people and their allies here’s some required reading. Bookmark it. 🧵 Image
“Transgender identity is complex – it’s unlikely we’ll ever be able to attribute it to one neat, contained set of causes, and there is still much to be learned. But we know now that several of those causes are biological.” filmsforaction.org/articles/betwe… ImageImage
Read 11 tweets
May 11, 2023
Recent study: no increase in death (cardiac or all causes) in ages 12-29 after mRNA vaccination. There was an increase in cardiac and all cause deaths after a SARS-CoV-2 infection. Image
Another study showed non-COVID-19 mortality rates were lower among COVID-19 vaccinated patients. There was no increased risk after vaccination.

sciencedirect.com/science/articl…
Read 8 tweets
Feb 7, 2023
Masks continue to trend so here is a quick thread to save as a reference on the importance of masking. Let’s start with the rationale behind it. 🧵
Multiple various studies have shown masks are helpful with reducing transmission (also see my pinned Tweet).
While preventing onward transmission is the key way masking helps there studies showing they can prevent infection as well.
Read 5 tweets

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