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Nov 29 • 13 tweets • 5 min read
I won't sugarcoat this fearmongering.

Candida auris typically infects patients with weakened immune systems. C. auris causes invasive candidiasis (fungemia) in the bloodstream impacting the CNS & multiple organs.
C. auris has attracted attention b/c of its drug resistance, earning the cool name "superbug". But, it's not supposed to infect 600 "weakened immunity" non-patients:
2018-329
2019-466
2020-753
2021-1,765
2022-4,616 (not including this recent outbreak)

cdc.gov/fungal/candida…
A gentle reminder the US/CDC abandoned the WHO's #PrecautionaryPrinciple in 2020. This is the IPC/CDC page for C. auris today, lot's of handwashing, zero isolation of vulnerable patients: Image
This is IPC/CDC recommendations for C. auris BEFORE the tweeting dotard attacked the WHO and attacked the scientific community. Patients are isolated and HCW are provided N95 respirators. There's zero evidence C. auris is airborne because IPC was never dependent on "evidence". Image
This was CDC's SARS PPE recommendation since 2007.

The US/CDC have whitewashed their website to remove any trace or evidence which can be used against them for removing standard Infection Prevention Controls against SARS: Image
The WHO always kept the same IPC/PPE guidance. If evidence of SARS airborne transmission was not known, the WHO's IPC guidance still recommends N95 respirators. Evidence doesn't matter!

In the real world, lack of evidence of risk, never trumps, lack of evidence of safety. Image
Why is it insane to attack the WHO for not acknowledging "evidence of airborne transmission"?

The CDC re-abandoned PPE for HCW well AFTER the evidence of airborne transmission is undeniable!

C. auris is really, really bad . . . that's not fearporn.

Wear the highest grade FFR (N95) with eye protection for your own health and safety.
Don't just take my word for it, listen to the doctors:
Don't want to take the doctor's word?
What about listening to the nurses?
This is twitter, you are free to ignore or retweet a bunch of rando tweet people all screaming bloody murder that HCWs are being denied N95 PPE:
The US's abandonment of the #PrecautionaryPrinciple due to scarcity over science is how it started. The US, UK, Canada are all eventually going to be liable for the significant neglect to abide to the long-standing N95 PPE standards.

cbc.ca/news/health/pr…
A most excellent thread discussing the aggravated growth of SuperBugs in North America. Yes, that's a thread from last year!

Someone give Laura Miers a Gold Check Mark!

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More from @RealCheckMarker

Reality Check Marker Profile picture
Nov 30
@NjbBari3 @farid__jalali All three of you are partially correct. I find it fascinating everyone here is batting around theories of autoimmune disorder when political forces have opened up a population level experiment but nobody is collecting data.
@NjbBari3 @farid__jalali Prior to this SARS outbreak the most common infection that lead to lymphopenia was HIV. Now we are seeing varying degrees of autoimmune disease but nobody is applying the simple AIDS tests of t-cell depletion!
@NjbBari3 @farid__jalali The trigger for cytokine response and cause of lymphopenia are more likely a result of prion creation of persistent viral infection which damages all systems including immunity.
Read 5 tweets
Reality Check Marker Profile picture
Nov 19
@EvanBlake17 These are interesting development but you seem to be using a oversimplification of ZeroCovid policy and are apparently unaware of medical diagnosis and treatment options recently developed by China.
@EvanBlake17 First, China’s ZeroCovid policy is mostly focused at international travellers and international points of entry. The “Managed Isolation” used by Australia, New Zealand, Hong Kong, Japan & Canada’s Northern Territories are the integral part of ZeroSARS.

who.int/health-topics/…
@EvanBlake17 I have breaking news; Chinese leadership was draconian before pandemic. But PH measures for pandemic was not draconian. Field hospital for infected is best example, often deemed “draconian”. However, US, UK & EU infected patients in ER next to “not-yet” infected is not draconian?
Read 13 tweets
Reality Check Marker Profile picture
Nov 18
Variant soup addition of CH.1.1. Appears to be a cousin of XBB and sister of BQ.1.1 with key G446X mutation present in spike protein.

What does this mean for transmission and severity of infection?
IFF CH.1.1 continues growth, means it’s a “cousin” mutation where previous antibodies from previous infection or vaccine immunity are being successfully evaded. CH.1.1 will likely outcompete BQ.1.1 (sister) and have concurrent community spread with XBB (or upcoming XBB mutation).
However, the bivalent mRNA vaccine and Novavax vaccine would continue to prevent severe infection, as long as the vaccine activated t-cell are still active. As long as those HCoV t-cells are ACTIVE, there’s active cross-immunity (only prevent death) for all possible SARS variant.
Read 9 tweets
Reality Check Marker Profile picture
Aug 29
Etiology of lung disease during & after acute phase is sequela from SARS–induced ARDS, not direct injury from SARS virus. Predictor & diagnose of ARDS need to include high inflammatory markers (MIS C/A). This why treatment anti-inflammatory & antifibrotic prevent lung fibrosis.
Undiagnosed/untreated Long-SARS patient show same mitochondreal dysfunction as ME/CFS patient; low metabolism, increased weight, blood pressure & high fasting blood glucose, insulin and cholesterol level. However, antifibrotic treatment significantly alleviate these symptoms.
Long-SARS is basically chronic inflammatory disease with t-cell defiency loss.

Is possible same-day HIV test for t-cell depletion detect Long-SARS (for most Long-SARS patient).

Follow up testing for a wide array of inflammatory markers, such as MCP-1, TNF-α, IFN-γ, and IL-6.
Read 7 tweets
Reality Check Marker Profile picture
Aug 28
@ColinDotNet First, important to establish theory vs fact. en.wikipedia.org/wiki/Human_cor…

It’s only theory A-HCoV-OC43 is recent BCoV to HCoV. Other theories are this occur 15K-8K yrs ago. Fact is evolution of OV43 has stopped. It’s an mRNA virus perfectly adapted to humans.
@ColinDotNet These are distinguished SARS knowledgeable who distinguish differences between influenza vs coronavirus.

Love this quote “based on how sloppy RNA polymerases are, coronaviruses shouldn’t exist”

cals.ncsu.edu/applied-ecolog…
@ColinDotNet Coronavirus are perfectly evolve zoological pathogen evolve billion yrs. Can survive in brood only two hosts, evading immunity, just re-infect back & forth. Many scientist never understand HCoV clear faster if immunity not activated, Omikron prove this.

assets.publishing.service.gov.uk/government/upl…
Read 15 tweets
Reality Check Marker Profile picture
Aug 28
@ColinDotNet As a SARS & MERS specialist I don’t subscribe to the mass extinction level theory. We know SARS results in long, slow death. In 5 years we will notice LTC homes closing & consolidation of homes - when they should be Booming. In 10 years we might realize anyone over 80 is rare.
@ColinDotNet HIV doesn’t kill during acute phase. HIV patient die early onset immunosenescence (inflammAging).

Unknown cancer.

Mysterious hepatitis.

Spontaneous bacterial encephalitis.

Death “FROM” HIV, not death “WITH” HIV!
@ColinDotNet Dr Pasteur struggle all his life to convince medical community of Germ Theory, finally put to rest “Spontaneous Miasma” of infectious diseases!
150 yrs later Twitter reverse all scientific knowledge. Even before pandemic, CJD had “Sporadic” classification when cause is unknown.
Read 5 tweets

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