‘I’m just carrying on’: vaccine gives brain cancer patient years of extra life

The revolutionary DCVax-L vaccine has allowed Nigel French to live a normal life seven years after a brain cancer diagnosis #DCVaxL $NWBO #CancerVaccine #Glioblastoma #Phase3

theguardian.com/science/2022/n…
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma $NWBO #DCVaxL #CancerVaccine #GBM

A Phase 3 Prospective Externally Controlled Cohort Trial

jamanetwork.com/journals/jamao…
More long-term Survivors, $NWBO #DCVaxL a personalized general therapeutic #CancerVaccine to treat any kind of solid tumor cancer anywhere in the body.

Other $NWBO investors, I think you'll find this book well worth reading or listening to... It's totally on point, #DCVaxL #CancerVaccine. @DrSidMukherjee

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More from @eastvillagetwt

Nov 30
@matthwilliams @NWBIO @braintumourrsch @BrainTumourOrg Dude, your conflict of interest is all over you and this criticism. Let the regulators do their jobs. You focus on your patients and BUSINESS interests. Let the regulators, patients and market decide what they would prefer. You’re disgracing yourself in the field.
@matthwilliams @NWBIO @braintumourrsch @BrainTumourOrg Let's recall that Optune costs £20,000 per month in the UK, or £240,000 per year, as long as the patient lives, an incredibly expensive treatment, which is why the NHS only covers it for a limited group of patients. It's burdensome, expensive & requires 18 hrs a day compliance.
@matthwilliams @NWBIO @braintumourrsch @BrainTumourOrg Call for NHS to fund £240,000 cancer treatment Optune

bbc.com/news/uk-englan…

I can see why you'd prefer such an expensive treatment, forever, over a treatment that could make potentiatlly he same number of patients free from treatment at all.
Read 9 tweets
Nov 11
$NWBO #DCVaxL New name #murcidencel
SNO Abstract, just released, for presentation by #DrLindaLiau on November 20th:

Background: Standard of care (SOC) and patient survival in glioblastoma have changed little in the past 17 years.
We evaluated in a phase 3 trial whether adding an autologous tumor lysate-loaded dendritic cell vaccine (murcidencel) to SOC extends survival. Patients and

Methods: Newly diagnosed glioblastoma patients were randomized 2:1 to either murcidencel or placebo.
Under a crossover design, all patients could receive murcidencel following tumor recurrence. All parties remained blinded regarding treatments before recurrence. Patients thus received murcidencel at new diagnosis (nGBM) or at recurrence (rGBM) following crossover from placebo.
Read 17 tweets
Aug 23
Northwest Biotherapeutics Announces -

Approval of Pediatric Investigation Plan (PIP) by MHRA

#DCVaxL $NWBO newsfilter.io/a/8ae27d3f0428…
“The development, regulatory review and regulatory approval of a PIP is a pre-requisite for application for approval of a new medicine for adult patients, such as DCVax®-L.”
“The Company submitted its proposed PIP to the MHRA in February 2022, and has been going through the regulatory review process since then.  On August 17, the Company received final approval of the PIP from the MHRA.”
Read 9 tweets
Aug 23
Dr. Keyoumars Ashkan #DrKeyoumarsAshkan Surgeon & professor, and he also ran the European trials for #DCVaxL from $NWBO
Professor Ashkan performs life-saving awake brain tumour surgery while patient plays violin! via @YouTube
Read 4 tweets
May 13
$NWBO DEDUCED RECKONING: Northwest Bio reports Phase 3 results.

#DCVaxL
@joanlappin

finance.yahoo.com/news/deduced-r…
1/ "Only 5% of glio patients survive for five years. So how stunning is it for DCVAX-L to see life expectancy at 60 months rise from 5.7% to 13%, an increase of 228%. Some patients have seen total remission glio and are cancer free more than a decade after treatment.
2/ For example, Brad Silver participated in the Phase 1 trial 17 years ago and is cancer free now."

Read 81 tweets

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