Jamir Pitton Rissardo Profile picture
Dec 8, 2022 15 tweets 7 min read Read on X
Rabbit syndrome!!!

“a peculiar extrapyramidal reaction”

Canadian psychiatrist André Villeneuve
1972, the first report

#MedTwitter #neurotwitter #EndNeurophobia #tweetorials

1/
Definition

“stereotyped vertical, rhythmic movements, similar to the chewing movements of a rabbit”

5 Hz
Lips produce a popping sound
Not tardive dyskinesia!
- persist stage I sleep

2/
Pathophysiology

- cholinergic system?

3/
Clinical tips
dyskinesia versus rabbit syndrome

i) tongue 10s extruded
- dyskinesia, tongue twist
- rabbit, no movement

ii) lips movement
- only vertical, rabbit syndrome
- all directions, dyskinesia

iii) movement pace
- fast & rhythmic, rabbit
- slower & irreg, dyskinesia

4/
Management

Long-term antipsychotic use, begins a few days after modification in psych treatment

Disappear after antipsychotic discontinuation

- anti-Parkinson's drugs, some

5/
Rabbit syndrome

💡after risperidone withdrawal

via: Medtext Publications

6/
Rabbit syndrome

💡amisulpride-induced

via: Srinivasa Teja

7/
Rabbit syndrome

💡paliperidone discontinuation

doi.org/10.1097/jcp.0b… via: J Clin Psychopharmacol

8/
Rabbit syndrome

💡functional

doi.org/10.5334%2Ftohm… via: Tremor Other Hyperkinet Mov (N Y)

9/
Differ

perioral & pharyngeal myorhythmia
- lower freq (1-4 Hz), when compared to rabbit syndrome

doi.org/10.1016/j.park… via: Parkinsonism Relat Disord

10/
Differ

tardive dyskinesia
- 🔄& irregular

via: Bác Sĩ Thần Kinh

11/
Differ

perioral myorhythmia
- lower freq (1-4 Hz), when compared to rabbit syndrome

💡 medullary compression by vertebral artery

doi.org/10.1007/s10072… via: Neurol Sci

12/
Differ

perioral myorhythmia
- lower freq (1-4 Hz), when compared to rabbit syndrome

💡EMG should be performed

doi.org/10.4103%2Faian… via: Ann Indian Acad Neurol

13/
NeuroTeach - Content

The blog contains all the threads and videos.

neuronland.blogspot.com/2022/11/neurot…

Have a great day!
Differ

hereditary chin trembling (geniospasm)

💡childhood
💡improve w/ aging
💡botox-sensitive

doi.org/10.1212/WNL.00… via: Neurology @sdo_henrique

14/

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More from @theneurolander

Feb 1
Syncope vs Seizure

Fainting by love in Philadelphia Museum of Art
The Doctor's Visit by Jan Steen

#Neurology #Seizure #Syncope #Neuroscience

1/ Image
Syncope spectrum

-Normal
-Prodrome→ early autonomic sx
-Presyncope→ near-syncope
-Intermediary→ gray-out/ syncope threshold
-Syncope
-Recovery

2/ Image
Clinical history

What EXACTLY happened before, during, and after the event?

-open-ended quest at begining, than close
-LOC, incotinence
-Witness and recurrence
*avoid term fainting
-Triggers (sleep dep, drugs, stand) vs premonitory symptoms

3/ Image
Read 19 tweets
Jan 29
Cognitive Changes

Alois Alzheimer (1864 – 1915), German psychiatrist and neuropathologist

1/ Image
Referral

-word-finding difficulty (tip-of-the-tongue phenomenon)
-memory complaints (often vague, sometimes language-related)
-dissect complaints into domains

2/
Cognitive Domains

Use SAMPLE

-Social→ behavior
-Attention→ focus
-Memory→ retention
-Perceptual/ visuospatial→ navigation
-Language→ only language
-Executive function→ multisteps

3/ Image
Read 22 tweets
Jan 25
Headache - Basics

Figure from Codex Vindobonensis 93 (12th century)

1/ Image
Primary or Secondary?

1st question - onset

Hyperacute→ think vascular
Acute/subacute→ broader ddx
Chronic→ reassure if unchanged

Use SNOOP4 for screen secondary causes

2/ Image
Characterize

-Pain features - "SOCRATES"
> quality (throbbing, pressure, stabbing)
> duration & frequency
> associated sx (photo/phonophobia, N/V, auto sx)

3/
Read 23 tweets
Jan 19
Diagnosing Neuropathy
Clinical Pearls

"There are numbness, tingling, and burning pains in the feet, with weakness of the legs, so that the patient walks with difficulty and unsteadiness"

Sir William Osler (1849 – 1919), Canadian physician

1/ Image
Presentation
Referral "neuropathy," self-dx googling numbness/tingling
-hard≠numbness≠tingling≠weak

-true negative sx (loss) are more specific
>unable feel floor T°
>unable sense sand/cold surfaces

-positive sx (gain) are non-SP
>dd: CVI, MSK, compression, positional
2/ Image
Localizing

P.neuropathy patterns
-stocking-glove distribution
>1st stocking (knee) level → 2nd hands: likely DM
-dist → prox progression in limbs
-symmetric sensory loss

3/
Read 22 tweets
Jan 12
Tuning Forks

"If you want to find the secrets of the universe, think in terms of energy, frequency, and vibration"

Nikola Tesla (1856 –1943), Serbian-American engineer

1/ Image
History

1550 Gerolamo Cardano - transmission of sound per skull
1684 Schelhammer - fork to differentiate hearing disorders
1711 John Shore - invented TF
1834 Johann Heinrich Scheibler - different frequencies
1855 - Weber test
1870 - technical improvements

2/
TF Parts

Prongs (wings), stem (handle), and foot (base)

3/ Image
Read 19 tweets
Oct 12, 2025
Head (Holocephalic) tremor

"... is just an irritation..."

Katherine Hepburn

1/ imdb.com/pt/name/nm0000031/?reasonForLanguagePrompt=browser_header_mismatch
ET

- no-no
- type 1 (enhanced) & 2 (msc activation not req for posture)
- ET meds, if no response botox



2/ youtube.com/shorts/uMA_wPY…
PD

- yes-yes
- jaw & lip→ PD



3/
Read 9 tweets

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