Autonomous Sensory Zones
(peripheral nerves)

Median nerve illustration by Guttmann (1939)

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1/
Definition

“regions where single nerve roots supply distinct and non-overlapping areas of skin”

- small portion of dermatome
- few nerve roots have such autonomous zones
- great variability

2/
Sensory zones

a.maximal zone: maximal area supplied by a peripheral nerve
- maximal=intermediate+autonomous

b.intermediate zone: area of overlap of the maximal zone of different peripheral nerves

c.autonomous zone: area exclusively supplied by a particular peripheral nerve
3/
Autonomous zones of various nerves:

A. Radial nerve
B. Median nerve
C. Ulnar nerve
D. Common peroneal nerve
E. Sciatic nerve

4/
Radial nerve

area: 1st dorsal web space of hand (Anatomical snuff box)

“according to some authors, radial nerve and common peroneal do not have autonomous zones although complete transection of the nerve results in sensory loss over the mentioned regions”

5/
Median nerve

area: distal phalanx (tip) of index finger (2nd finger)
- tip of thumb (other possible area)

6/
Ulnar nerve

area: distal phalanx (tip) of little finger (5th finger)

7/
Common peroneal nerve

area: central strip on dorsum of foot

“according to some authors, radial nerve & common peroneal do not have autonomous zones although complete transection of the nerve results in sensory loss over the mentioned regions”

8/
Sciatic nerve

area: mixed pattern of common peroneal nerve and posterior tibial nerve

9/
Deep peroneal nerve

area: 1st dorsal web space

10/
Posterior tibial nerve

area: sole of foot

11/
Why is important to know the autonomous sensory zones?

“anesthesia in an autonomous zone indicates a complete lesion of that particular nerve”

12/
MRC grading of sensory recovery tested on autonomous zone

13/
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More from @theneurolander

Dec 19
Meningeal signs

“Brudziński neck sign, Brudziński symphyseal sign, Brudziński cheek sign, Brudzinski's reflex”

Polish pediatrician Józef Polikarp Brudziński (1874–1917)

#MedTwitter #neurotwitter #EndNeurophobia #tweetorials

1/ Image
Definitions

Meningitis
-inflammation of leptomeninges & underlying subarachnoid CSF

Meningismus
-morbid state characterized by meningitic syndrome (triad: headache, photophobia, nuchal rigidity)

Meningism
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Mechanism

“maneuvers used to elicit meningeal signs produce tension on inflamed and hypersensitive spinal nerve roots, and the resulting signs are postures, protective muscle contractions, or other movements that minimize the stretch and distortion of the meninges and roots”

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Inverted & Perverted Reflexes

The first description of the paradoxical (inverted) triceps reflex

French neurologist Alexandre-Achille Souques (1860–1944)

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1/ Image
Definition

“elicitation of the movement opposite to that normally seen when the reflex is elicited”

2/
Mechanism

“a lesions simultaneously affecting the roots and spinal cord”

Damaged root
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Damaged spinal cord
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Dec 14
Myotonic disorders!

“after a fright, or in an unexpected joyous movement, this convulsive constriction occurs in all limbs…the victim can not stand upright”

Prussian physician Asmus Julius Thomas Thomsen (1815–1896)

#MedTwitter #neurotwitter #EndNeurophobia #tweetorials

1/ Image
Definition

“difficulty in relaxation of a muscle after maximum voluntary contraction”

It can be specifically
- aggravated by conditions
- affecting regions of the body
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Myotonic or Tennessee fainting goat

“important in history due to role of chloride channel in muscle excitation”

- 1880s, Marshall County
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via: jimmywan87

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Dec 10
Dermatome!!!

“Dermatomal man, early twentieth century”

University of Edinburgh Image Collections

#MedTwitter #neurotwitter #EndNeurophobia #tweetorials

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History

“dermatomal charts are primarily derived from 3 sources”

Head & Campbell
-herpetic eruptions

Foerster
-rhizotomy in chronic pain
-dermatomal overlap

Keegan & Garrett
-various diseases
-exam & surgical correlate: 53%

American neurosurgeon John Jay Keegan(1889-1978)
2/
Definition

“area of skin in which sensory nerve derive from a single spinal nerve root”

- 31 spine segments
8C + 12T + 5L + 5S + 1 coccygeal
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3/
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Dec 9
Hereditary Ataxias!!!
Spinocerebellar ataxias (SCA)

“SCA1 …. the unstable CAG trinucleotide repeat expansion”

American geneticist Harry T. Orr

#MedTwitter #neurotwitter #EndNeurophobia #tweetorials

1/
SCA definition

“complex group of heterogeneous degenerative diseases of the cerebellum and its connections”

2/
Worldwide distribution of SCA subtypes

21% SCA3, Brazil & Portugal
15% SCA2, India & Singapore
15% SCA6, Japan & Germany
6% SCA1, South Africa
5% SCA7, South Africa
3% SCA8, worldwide

<1% rare
SCA 10, SCA 12, SCA 14, SCA17

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Dec 8
Dancing larynx!!!

“a variant of palatal tremor?”

British neurologist Anette-Eleonore Schrag
1999, first description
@UCLIoN

#MedTwitter #neurotwitter #EndNeurophobia #tweetorials

1/ Image
Definition

“rhythmic vertical laryngeal cage movements of varying frequency with synchronous movements of the tongue, posterior pharynx, and the palatopharyngeal arch”

- not affecting uvula

2/ Image
Pathophysiology

Variant of palatal tremor
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Functional

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