1- In these images, I want to draw attention to two tips. First, that there is a combination of patterns (Lichenoid + psoriasiform). A combination of different reaction patterns should always make you think of syphilis.
2- Another tip is what I drew: Rete ridges. Dr Elston's famous quote for them is sexy ridges. Very characteristic of syphilis.
Next step: Thinking about syphilis, look for plasma cells.
It is worth noting that in most cases we will see these cells, but if you do not find them, do not rule out the possibility of syphilis. Then confirm with a spirochete stain or serological test.
See more tips like this in the dermatopathology section of pathplus.app
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