Discover and read the best of Twitter Threads about #pathology

Most recents (24)

Human #intestinal #spirochetosis:
✔️#sexual #transmitted infections
✔️of the large intestine by anaerobic spirochetes of the genus Brachyspira spp.

🖊️A De Gea, @alfredomaldo ,@clarapath, @MarianaDazAlmi1, @alirri, Raquel Escudero, et al.
👇… Colonoscopic biopsy. In rou...
@alfredomaldo @clarapath @MarianaDazAlmi1 @alirri Gastrointestinal symptoms such as abdominal pain, proctitis, or chronic diarrhea are the most common manifestations.

Most cases with accompanying symptoms show improvement with metronidazole antibiotic therapy.

Routine staining methods (haematoxylin & eosin & Warthin-Starry) can identify spirochetes on the surface of enterocytes.
Histologically, characteristic findings include a decrease in microvilli &a predominantly eosinophilic inflammatory infiltrate.

#Pathologists #pathology Colonoscopic biopsy compare...
Read 12 tweets
@drcole12 is making mistakes here that even a #pathology trainee would be embarrassed to make. His core claim is that spike protein from vaccines is inducing blood clotting. This is generally false. Image
The source of his data is @ArneBurkhardt , who first off, makes so many logical errors that it deserves a thread of its own.
Next, Cole presents slides from Burkhardt's presentation free of context, to give the reader a veneer of legitimacy, but in reality, all deceased people have blood clots. The basis of his claim is essentially the slide shown above, with an absence of awareness of basic dying.
Read 12 tweets
#Pathology #COVID19 #spike #autopsy The German pathologist @ArneBurkhardt is getting a lot of stuff wrong with his presentations to the EU parliament and other interested parties on his supposed technique to determine vaccine related adverse events after autopsy.
Here are all his logical holes. @EuroParlPress @Europarl_EN @Europarl_Photo
First off, its not cool to represent yourself as a member of a pathology group in Reutlingen when you are no longer officially employed there. A qualifier like "former" would be better. The people who actually work there: ImageImage
Read 25 tweets
Finally a quiet moment😓.
This is an interesting case that came through this week:

76 F Rt Forehead.
SCC vs NUB #skin #dermpath #dermatology #dermatopathology #pathology #pathtwitter
low power 1st: ImageImageImageImage
Next is higher power at 100x ImageImageImage
And now 200x ImageImageImage
Read 6 tweets
Hey #PathTwitter & #MedTwitter, check out Pedro Pascal transformed into Pedro Pathcal as different stains & methods in histo/cyto/pathology!

Who said #Pathology & #LabMed can't be fun? Embrace your inner histo/cyto/pathologist and celebrate #LabWeek2023! (4/23 - 4/29) 🧬🔬🎭 Image
Hematoxylin, fancy name for a natural dye derived from tropical trees logwood and Brazilwood. It binds to acids (ie.DNA & RNA), turning them a lovely shade of blue or purple. It's a daily go-to in pathology labs! Check out PMID: 30001639 for a great read on its history and usage. Image
Eosin? More like "Oh, so pink!" This synthetic dye binds to all things positive in cells and ECM, highlighting muscles and connective tissues in shades of pink and red. It's a routine go-to in pathology labs along with hematoxylin! #PathMemes #LabLife Image
Read 26 tweets
Feeling lucky 🎰?
🍑vs 🍓.
These 2 lesions are similar but not the same. Let’s take a closer 👀 look…
#skin #dermpath #dermatology #dermatopathology #pathology #dermresident #dermboards #dermboardsstudying #pathologist #surgicalpathology #surgpath #pathtwitter #pathresident ImageImageImageImage
Let’s look closer at peach 🍑 ImageImageImageImage
Now closer at strawberry 🍓 ImageImageImage
Read 8 tweets
A pathologist’s first words:

“red is dead, blue is bad.”

This picture of a slide encapsulates both in one image.

#skin #dermpath #dermatology #dermatopathology #pathology #pathologist #surgicalpathology #surgpath #pathtwitter #pathresident #trishtorial Image
Only 53…leg. Didn’t suspect it. Only hx of prior nevi removed.
I suppose it’s obvious where the diagnosis is headed… ImageImageImageImage
I only did 3 stains, probably could have used just 1, but with the lack of history I guess it felt right to super-prove it . ImageImageImageImage
Read 7 tweets
With #USCAP2023 approaching, I have been conversing with @MSKPathology fellows about how to make the most of the meeting

Thought I would share some ideas here (thread🧵):

1. Large professional mtgs can be overwhelming & IMO, require a strategy in order to maximize gains
👇🏻 1/ Image
2. Select sessions to attend:

Review the conference website:

Select "Schedule" under the "Program" drop-down menu for a day by day, hour by hour view #USCAP2023 👇🏻 2/ Image
3. Focus, Focus, Focus

Too many concurrent sessions at #USCAP2023 to randomly select

Residents: make ACTIVE choices - is there a subspecialty I'm considering fellowship in? is there a technology (#molecpath, #digitalpathology, #AI) that I want to learn more about? 👇🏻 3/
Read 18 tweets
A 71-YO therapy for multiple mieloma, voriconazole for Aspergillus fumigatus sinusitis, prophylaxis with TMP-SMX: febrile neutropenia, nodular lesion on abdominal wall
CT: pulmonary nodule unchanged in last a month
🔬biopsy of pulmonary nodule?

#Pathologists #haematology Histopathology of the fine-...Image
🔬: Histiocytic process with granular basophilic cytoplasm and Michaelis-Gutmann bodies (arrows), positive for calcium with von Kossa special stain (arrowhead); findings pathognomonic for malakoplakia.

🧫of the pulmonary nodule:➖
🧫biopsy of the abdominal wall lesion: Rhodococcus equi resistant to TMP-SMX, but susceptible to rifampicin, vancomycin, azithromycin, ciprofloxacin, & imipenem.
Read 8 tweets
A 17-YO: a 3-week of dizziness, headache, & weakness of the R leg

MR: ring-enhancing lesions in the frontal lobe & basal ganglia on the L side (A; T1-W) as well as surrounding edema & midline shift (B; T2-W)

DOI: 10.1056/NEJMicm2202196
#neurology #radiology #IDTwitter
IgG ab for Echinococcus multilocularis & E. granulosus: ➖

Surgical excision🔬: necrotic tissue, granulomatous inflammation, echinococcal laminated membrane (C, arrow) & an intact cyst (D, arrow)

RT-PCR: ➕for E. multilocularis

#parasitology #Pathologists #pathology
CT imaging of the chest and abdomen did not show any other sites of disease.


DOI: 10.1056/NEJMicm2202196
#microbiology #MedTwitter #Doctor
Read 6 tweets
A 14-yo ♂️ lived on a farm: a 1-month history of episodic headaches, vomiting, & papilledema
MR: a multiloculated cyst of the brain (A) with a hypointense rim and small projections in T2 phase (B, arrow)

DOI: 10.1056/NEJMicm2208104
#neurology #radiology #pediatric Image
Findings suggestive of CYSTIC ECHINOCOCCOSIS.

CT of the body: no other sites of disease.
A craniotomy was performed, during which saline irrigation was used to separate the cyst wall from the brain to avoid rupture.

DOI: 10.1056/NEJMicm2208104
#IDtwitter #parasitology Image
🔬: an echinococcal laminated membrane lined by a germinal layer with daughter cysts (Panel D, arrows) and protoscolices (inset, arrows) with hooklets (arrowhead).


#microbiology #Pathologists #pathology Image
Read 5 tweets
“Premeditated Manslaughter Coordinated at the Highest Levels” – Part 2 -Psychopathic democide might be eligible for forgiveness in rare circumstances, but blanket amnesty is not in the cards for crimes against humanity - by @TraderStef #Nuremberg2 #Amnesty… Image
#Nuremberg2 #Amnesty? - “Plandemic 3” Trailer – Seeing Through The Propaganda…
#Nuremberg2 #Amnesty? #democide - Jr. covering for daddy, sooo late and behind the curve by a couple+ years, is pathetic - not humble
Read 99 tweets
A 32-YO♀️ from Guatemala, Ph+ B-ALL post #chemotherapy: #dyspnea
CT: ground-glass opacities (2A yellow box), interstitial pulmonary edema with septal thickening (2B yellow circles), & pericardial effusion (2C yellow arrows), lymph nodes (2D yellow arrows)
Due to normal ejection fraction, the differential diagnosis of dyspnea included non-cardiogenic pulmonary edema, pneumonitis secondary to chemotoxicity, and infection.
#haematology #radiology #IDtwitter
She progressed to acute hypoxic respiratory failure.

🔬bronchoalveolar lavage: numerous larvae (3A,3B) with short buccal grove (arrow head) and prominent genital primordium (arrow) consistent with STRONGYLOIDES HYPERINFECTION

#lungdisease #parasitology #Pathologists
Read 7 tweets
Two images to think about in this diagnosis.
What tips can we list in these two images?
What did I sign?
Next step?

#dermpath #pathology ImageImage
1- In these images, I want to draw attention to two tips. First, that there is a combination of patterns (Lichenoid + psoriasiform). A combination of different reaction patterns should always make you think of syphilis.
2- Another tip is what I drew: Rete ridges. Dr Elston's famous quote for them is sexy ridges. Very characteristic of syphilis.
Next step: Thinking about syphilis, look for plasma cells.
Read 4 tweets
Whatever we do in medicine has a history.

Hematologists take a sample from the bone marrow (BM) every day. But where do we come from?

A short history 🧵 about BM biopsy.

#MedTwitter #hematology #pathology
-oldest known procedure carried out on mankind
-8-10k years old skulls with evidence of medical intervention (found in 🇪🇺, Africa, Asia, New Guinea, Tahiti, New Zealand)
-for headaches, mentalities
-many "patients" survived (evidence of healing of their bones)
Celsus (c. 25 BC - c. 50 AD):
-described "trephination"
-recommended it for removal of damaged cranial bones and as a therapeutic measure for relieving headaches
-with a specialized instrument, a surgical modiolus or crown trephine
-encyclopedia "De medicina" before 47 CE
Read 19 tweets
A 17-MO♀️, Morocco: fever, pallor, epistaxis, gingival petechiae, lower limbsedema, & hepatosplenomegaly.

Pancytopenia, hypoalbunemia.
Triglyceridemia, ferritinemia, LDH & fibrinogen:⬆️
Direct Coombs test:➕

🔬myelogram: ?

#parasitology #haematology #Pediatrics
Myelogram revealed the presence of leishmania bodies and figures of hemophagocytosis.

#Pathologists #microbiology #IDtwitter
The patient was put on liposomal amphotericin B and corticosteroid therapy with good clinical and biological evolution.

#MedTwitter #Doctor
Read 9 tweets
01/ Buckle up, everyone, it’s time for a Tweetorial. Been working on this one for a while. This time, I’ll focus on the most common mesenchymal malignancy of the digestive tract: gastrointestinal stromal tumor (GIST). #pathology #gipath #PathTwitter
02/ GIST arises from the interstitial cells of Cajal. It can originate anywhere in the GI tract, though most cases occur in the stomach or small bowel. Rectum cases are uncommon, and GIST is very rare in the esophagus, colon, or appendix.
03/ Old terms for GIST include GANT (gastrointestinal autonomic nerve tumor) and leiomyoblastoma. These terms are no longer used, though you may run across them in older literature.
Read 80 tweets
A 17-year old male presented with a breast lump . Gross and Microscopic images from the excised lump ( shown in the images). Identify the true statement? (Options in the comments) #pathology #PathTwitter #PathTwitterFamily #pathtweetorial #tweetorial #MedTwitter #pathboards ImageImageImage
Diagnosis is juvenile papilomatosis.
Observe "swiss-cheese appearance" in gross and microscopy.
Other conditions with Swiss cheese appearance Image
Read 7 tweets
🚨 Ever find yourself in need of a cellular cell block for #cytopath workup? Here is my "bulletproof" way of getting it!

You'll need:
1. Conical vial (lab)
2. Sheep's agar (micro)
3. Plating loop (micro)
4. Plasma/Thrombin (blood bank)
5. Wrapping paper (histo)


#pathology Image
1. Spin down your fluid in a conical vial at high rpm (~1200) for 6-8 mins and remove supernatant

You'll have a soft slurry.

2. Add 3 drops plasma, 3 drops thrombin and spin again to form clot

#pathology #cytopath
2/5 Image
3. Cut out 2 squares of agar

4. In one square, scrape away a shallow "bowl" to place your clotted cell slurry

5. In the other square, trim in 1/2 and use the thin flap to cover the slurry in an agar sandwich. Agar protects pellet from dissolution!

#pathology #cytopath
3/5 ImageImageImage
Read 5 tweets
What we examined. What the cohort was. How they died. An autopsy review from late last year. Our first initial urgent findings. #pathologist #histpathology #PathTwitter #CPC22 #MedTwitter
Tissue with lymphocytic infiltration.
(Blue dots: lymphocytes). The tissue is inflamed.
Example 1
Tissue with lymphocytic infiltration.
(Blue dots: lymphocytes). The tissue is inflamed. The muscle fibres are destroyed.
Read 23 tweets
Pathology Report for Fungal Infections #tweetorial

1/9 Histopathological diagnosis of an invasive fungal infection should be PRIMARILY DESCRIPTIVE and must include:
Follow the thread to discover.
📌 The order can vary but try to include them all.
#PathTwitter Image
2/9 🍄 The fungal elements you find and their amount:

- Hyphae: Are they Pigmented or non-pigmented, septation and branching (acute angle, right angle or both)

- Yeasts: Their size, form and budding

- Pseudohyphae

#DCF_path #pathology #pathologist
#PathTwitter Image
🍄 Invasion of the tissues and vessels

🍄 The host’s reaction to the infection (inflammation, necrosis, or hemorrhage)

#DCF_path #pathology #pathologist
#PathTwitter ImageImage
Read 9 tweets
Sept challenge! recently taught @yalederm, trying to channel thinking, fast and slow:thru 9/30, 1 #dermpath/day, 10 AM EST (please retweet!) - can you mentally match each posted WSI (not all rep'ed here) with these clinical? in other words, what'd be the #histopath? @kikofordocs Image
3rd photo courtesy @JeffGehlhausen , 4th courtesy Dr. Sarah Kim @yalederm, rest courtesy @yalederm
Around September 30th, there will be "review" and an index of these cases on KiKo (credit to @forthejon for a great platform!) - please share with anyone interested in a case/day @JMGardnerMD @RoxanaDaneshjou @michi_shinohara @MishaRosenbach @DrStevenTChen @sunpungi
Read 6 tweets
When your heart is the most important organ. #Pathologists #Cardiology #cardiologist #MedTwitter #Histopathology #pathology ImageImageImageImage
The heart shows inflamation and lymphocytes attacking the organ seeking the combat the SP #Cardiotwitter #MedTwitter #Pathologists #Cardiology #Histopathology ImageImageImageImage
Read 3 tweets
1) Welcome to our new #accredited #tweetorial on the Pathophysiology of #DKD in #T2D: Traditional Teaching and New Insights. Our expert author is Hans-Joachim Anders, MD, @hjanders_hans from @LMU_Uniklinikum of @LMU_Muenchen
2) This #accredited #tweetorial series on the foundations of #kidneydisease #DKD through the lens of #T2D is supported by an independent educational grant from the Boehringer Ingelheim/Lilly Alliance and is intended for healthcare providers.
3) This activity is accredited for #physicians #physicianassociates #nurses #NPs #pharmacists. Past programs still eligible for credit can be found at Faculty disclosures & accreditation statement are at FOLLOW US!
Read 48 tweets

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