Discover and read the best of Twitter Threads about #pathology

Most recents (8)

How about a #Tweetorial with no ending? A document that can be added to at any time? Can it work? Let’s find out!

1/
This #pathtweetorial will address the entity know as “talc granulomatosis” and review the literature, including old papers!

#pathology #pulmpath #granuloma
2/
I did a quick search to find the first time “talc granulomatosis” was used as a term for lung lesions caused by excipients in pills, and came across this 1970 paper. Were Hopkins and Taylor the first to coin the term? Correct me if I’m wrong @yro854

ncbi.nlm.nih.gov/pubmed/5410600/
3/
But first, let me give you a taste of what talc granulomatosis looks like, courtesy of Extra Super Duper Pathologist @DrjohninNE

The main finding is foreign body granulomas surrounding birefringent particulate matter (excipients) in the interstitium

Read 14 tweets
Today's shift has been a rollacoaster of emotions which ended in a very sombre yet stark reminder of the importance of team work,effective communication & most importantly the value of life.#biomedicalscientist #pathology #NHS #Haematology #transfusion @IBMScience

A LONG THREAD:
I started my late shift today at 12pm, I am a Biomedical scientist and I work in the haematology and transfusion laboratories at a busy urban general hospital. I started in the haem dept helping process full blood counts, reviewing results & running countless add on tests.
This is normal for a busy large hospital. I was then asked to pop into the transfusion lab to review my training for manual crossmatches which has now been approved to carry out on analysers. I get as far as starting my crossmatch at 2.15pm, where upon I get a call from
Read 24 tweets
1/
Necrosis = cell death (unlike apoptosis, it does not occur naturally and is not programmed)

This short #Tweetorial shows you some of the histologic flavors of necrosis. The stain in each of these pics is hematoxylin-eosin (H&E)

#pathology #pulmpath #pathtweetorial
2/
First a question to test your knowledge. Necrosis with large numbers of neutrophils is called:
3/
And now a few examples. Necrosis in colorectal carcinoma is often described as “dirty” because it contains nuclear debris. This makes it look purplish instead of pink.

#gipath #MedEd
Read 14 tweets
1/
This is the beginning of a #tweetorial or #pathtweetorial on a mystery topic. Fear not, it’ll become evident soon what we’re talking about. But first I’ll show you an image. These serpiginous fibroblast plugs are diagnostic if organizing pneumonia (formerly BOOP)
2/
In MOST cases of organizing pneumonia seen on lung biopsy, the etiology is not evident on histology. But sometimes, there is a clue. Examine this pic closely and then see if you can answer the quiz in the next tweet in this thread.
3/
What does the pic in the previous tweet show?
Read 24 tweets
1/#Tweetorial #papillary #fibroelastoma for
#ASEchoJC 10/23

🐙= #PFE 1975 named #papillary #fibroelastoma by #armed #forces #institute of #pathology

#papilloma 1973

#Collagen core with elastic fibers & matrix covered by endothelium sheath
Attached by stalk
multiple fronds
2/ What is the incidence of #PFE 🐙 compared to #myxoma (diagnosed in same time period)?

#PFE 511 vs. #myxoma 112

#PFE incidence ~1/1000

common “benign”primary ❤️tumor #modern #EchoFirst (Most common @MayoClinicCV)

#myxoma (autopsy based prevalence)

bit.ly/2Am05Y9
3/How to tell if a #PFE🐙by #echofirst ?
(Vs.Atypical myxoma,SBE,
Llambl’s)
small mobile mass attached #endocardial surface frondlike extensions #independent motion stippled border
Usually on atrial surface of AV valves or either side of semilunar valves,🚫interfere valve Fxn
Read 10 tweets
1/
It’s time for a #tweetorial on hypersensitivity pneumonitis. It’s a greatly misunderstood entity. Potentially treatable, so can be very good news. OTOH, misdiagnosing UIP as chronic hypersensitivity pneumonitis can be very bad.

Follow this thread for a #pathtweetorial
2/
Let’s start with a poll regarding a common misconception. What is the predominant inflammatory cell in hypersensitivity pneumonitis?
3/
Hypersensitivity pneumonitis is an inflammatory reaction that occurs in individuals (classically never-smokers) who are exquisitely sensitive to an organic antigen.

Obvious exposures (moldy hay=farmer’s lung) can be fairly straightforward to recognize clinically.
Read 20 tweets
Tweetorial on carcinoid tumor of the lung. I’ll add to it little by little every week 😊

#pathology #pulmpath

1/
Carcinoid tumor is the lower grade end of the spectrum of neuroendocrine tumors in the lung.

Caution: lung terminology is different from GI tract terminology
2/
In the lung, the terminology is
✴️ Typical carcinoid tumor
✴️ Atypical carcinoid tumor
✴️ Small cell carcinoma
✴️ Large cell neuroendocrine carcinoma

We don’t terms such as “well differentiated NET” because...this is #pulmpath and we are special 😜
3/
Carcinoid tumors are very similar on H&E to low grade NE tumors in the GI tract or pancreas. Nesting, odd patterns, bland cytology, granular chromatin (“salt and pepper”)

Read 16 tweets
Something for the new path residents starting their journey

An A-Z of lymph node pathology

Some nice pictures of different lymph node pathology that you can commit a neuron or two?

One letter each day.

#hemepath #pathology #lymphnode #hematology #FOAMed
An A-Z of lymph node pathology.

[A] Amyloidosis => Look in nodes from patients with MZL, LPL or plasma cell neoplasms

Ref: ncbi.nlm.nih.gov/pubmed/3539760

#hemepath #pathology #lymphnode #hematology #FOAMed
An A-Z of lymph node pathology.

[A] Angiomyomatous hamartoma => Usually incidentally enlarged inguinal node in young males ... bands of smooth muscle reaching to edge of cortex +/- hilar fat.

Ref: iv.iiarjournals.org/content/26/3/4…

#hemepath #pathology #lymphnode #hematology #FOAMed
Read 38 tweets

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